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TPCN1 TPCN1 G3VAA5_SARHA G3VAA5_SARHA TRPA1 TRPA1 CACNA1F CACNA1F CNGA1 CNGA1 G3VEE0_SARHA G3VEE0_SARHA G3VEU9_SARHA G3VEU9_SARHA CACNA1S CACNA1S G3VFT4_SARHA G3VFT4_SARHA ITPR2 ITPR2 SCN3A SCN3A G3VIA9_SARHA G3VIA9_SARHA CATSPER3 CATSPER3 RYR1 RYR1 TRPM8 TRPM8 CNGA4 CNGA4 TRPM5 TRPM5 TRPM2 TRPM2 PKD2L1 PKD2L1 TRPV3 TRPV3 PKDREJ PKDREJ PKD2 PKD2 LOC111720221 LOC111720221 G3VQB3_SARHA G3VQB3_SARHA TRPV6 TRPV6 CACNA1G CACNA1G PKD1L2 PKD1L2 ITPR3 ITPR3 SCN10A SCN10A SCN2A SCN2A KCND2 KCND2 SCN11A SCN11A HCN3 HCN3 PKD2L2 PKD2L2 TRPV4 TRPV4 TRPM6 TRPM6 TRPM1 TRPM1 CACNA1D CACNA1D G3WV52_SARHA G3WV52_SARHA TMEM266 TMEM266 TRPC5 TRPC5 KCND3 KCND3 NALCN NALCN TRPM3 TRPM3 SCN8A SCN8A HCN2 HCN2 RYR2 RYR2 CNGA3 CNGA3 G3WDE0_SARHA G3WDE0_SARHA CACNA1H CACNA1H G3WEK1_SARHA G3WEK1_SARHA TRPC4 TRPC4 CNGA2 CNGA2 SCN1A SCN1A TRPM7 TRPM7 ITPR1 ITPR1 CACNA1I CACNA1I CACNA1E CACNA1E TRPV2 TRPV2 SCN4A SCN4A CACNA1A CACNA1A LOC100919755 LOC100919755 CACNA1B CACNA1B CATSPER2 CATSPER2 CACNA1C CACNA1C TRPC1 TRPC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TPCN1Two pore segment channel 1. (819 aa)
G3VAA5_SARHAUncharacterized protein. (755 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1126 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1917 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (690 aa)
G3VEE0_SARHAUncharacterized protein. (782 aa)
G3VEU9_SARHASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1876 aa)
G3VFT4_SARHAANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (792 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2704 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1950 aa)
G3VIA9_SARHAIon_trans domain-containing protein. (106 aa)
CATSPER3Ion_trans domain-containing protein. (202 aa)
RYR1Ryanodine receptor 1. (4886 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1103 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (541 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1138 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1518 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (760 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (790 aa)
PKDREJUncharacterized protein. (2140 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (927 aa)
LOC111720221Ion_trans domain-containing protein. (176 aa)
G3VQB3_SARHAUncharacterized protein. (639 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (727 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2397 aa)
PKD1L2Uncharacterized protein. (2457 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2665 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1973 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1920 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (746 aa)
PKD2L2Polycystin 2 like 2, transient receptor potential cation channel. (455 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2027 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1636 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1211 aa)
G3WV52_SARHACa_chan_IQ domain-containing protein. (801 aa)
TMEM266Transmembrane protein 266. (544 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (984 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (369 aa)
NALCNSodium leak channel, non-selective. (1477 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1275 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1978 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (524 aa)
RYR2Uncharacterized protein. (3999 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (709 aa)
G3WDE0_SARHAUncharacterized protein; Belongs to the potassium channel family. (259 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2177 aa)
G3WEK1_SARHAUncharacterized protein. (256 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (975 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (665 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1994 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1863 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2696 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1834 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2138 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (753 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2011 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2214 aa)
LOC100919755Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1992 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2075 aa)
CATSPER2Cation channel sperm associated 2. (530 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2069 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (737 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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