(38 nodes) N-Glycan biosynthesis network (Sarcophilus harrisii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	MGAT5B	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B. (791 aa)
	MAN1A2	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (342 aa)
	FUT8	Fucosyltransferase 8; Belongs to the glycosyltransferase 23 family. (377 aa)
	LOC100916939	Uncharacterized protein. (535 aa)
	ALG5	ALG5 dolichyl-phosphate beta-glucosyltransferase. (324 aa)
	ALG3	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol. (375 aa)
	GANAB	Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (965 aa)
	LOC100930797	Uncharacterized protein. (138 aa)
	MGAT1	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (439 aa)
	G3VUB2_SARHA	Uncharacterized protein. (351 aa)
	MGAT2	Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (449 aa)
	SRD5A3	S5A_REDUCTASE domain-containing protein. (198 aa)
	DPM3	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
	DDOST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (356 aa)
	B4GALT1	Uncharacterized protein. (281 aa)
	MGAT4C	MGAT4 family member C. (467 aa)
	MGAT4A	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A. (550 aa)
	MAN2A2	Alpha-mannosidase. (1152 aa)
	DAD1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (141 aa)
	ST6GAL1	ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (405 aa)
	MAN1B1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (625 aa)
	MAN1A1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (359 aa)
	ALG1	Glycos_transf_1 domain-containing protein. (402 aa)
	MGAT5	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (743 aa)
	ST6GAL2	ST6 beta-galactoside alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (517 aa)
	MGAT3	Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase. (545 aa)
	STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B. (740 aa)
	TUSC3	Tumor suppressor candidate 3. (363 aa)
	ALG2	ALG2 alpha-1,3/1,6-mannosyltransferase. (349 aa)
	RPN1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (605 aa)
	B4GALT3	Beta-1,4-galactosyltransferase 3. (393 aa)
	MOGS	Mannosyl-oligosaccharide glucosidase. (766 aa)
	ALG12	Mannosyltransferase. (483 aa)
	RPN2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (650 aa)
	STT3A	STT3 oligosaccharyltransferase complex catalytic subunit A. (706 aa)
	DPM1	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (266 aa)
	DOLK	Dolichol kinase. (525 aa)
	DOLPP1	Dolichyldiphosphatase 1. (238 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG1	ALG12	ENSSHAP00000015264	ENSSHAP00000020087	Glycos_transf_1 domain-containing protein.	Mannosyltransferase.	0.714
ALG1	ALG2	ENSSHAP00000015264	ENSSHAP00000019380	Glycos_transf_1 domain-containing protein.	ALG2 alpha-1,3/1,6-mannosyltransferase.	0.991
ALG1	ALG3	ENSSHAP00000015264	ENSSHAP00000004891	Glycos_transf_1 domain-containing protein.	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.	0.756
ALG1	ALG5	ENSSHAP00000015264	ENSSHAP00000004820	Glycos_transf_1 domain-containing protein.	ALG5 dolichyl-phosphate beta-glucosyltransferase.	0.801
ALG1	DAD1	ENSSHAP00000015264	ENSSHAP00000012080	Glycos_transf_1 domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.407
ALG1	DOLK	ENSSHAP00000015264	ENSSHAP00000022323	Glycos_transf_1 domain-containing protein.	Dolichol kinase.	0.719
ALG1	DPM1	ENSSHAP00000015264	ENSSHAP00000022143	Glycos_transf_1 domain-containing protein.	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.	0.979
ALG1	DPM3	ENSSHAP00000015264	ENSSHAP00000008275	Glycos_transf_1 domain-containing protein.	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.	0.937
ALG1	GANAB	ENSSHAP00000015264	ENSSHAP00000005046	Glycos_transf_1 domain-containing protein.	Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.	0.493
ALG1	LOC100930797	ENSSHAP00000015264	ENSSHAP00000005860	Glycos_transf_1 domain-containing protein.	Uncharacterized protein.	0.972
ALG1	RPN1	ENSSHAP00000015264	ENSSHAP00000019419	Glycos_transf_1 domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.504
ALG1	STT3A	ENSSHAP00000015264	ENSSHAP00000020482	Glycos_transf_1 domain-containing protein.	STT3 oligosaccharyltransferase complex catalytic subunit A.	0.485
ALG1	STT3B	ENSSHAP00000015264	ENSSHAP00000018381	Glycos_transf_1 domain-containing protein.	STT3 oligosaccharyltransferase complex catalytic subunit B.	0.485
ALG12	ALG1	ENSSHAP00000020087	ENSSHAP00000015264	Mannosyltransferase.	Glycos_transf_1 domain-containing protein.	0.714
ALG12	ALG2	ENSSHAP00000020087	ENSSHAP00000019380	Mannosyltransferase.	ALG2 alpha-1,3/1,6-mannosyltransferase.	0.553
ALG12	ALG3	ENSSHAP00000020087	ENSSHAP00000004891	Mannosyltransferase.	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.	0.969
ALG12	ALG5	ENSSHAP00000020087	ENSSHAP00000004820	Mannosyltransferase.	ALG5 dolichyl-phosphate beta-glucosyltransferase.	0.969
ALG12	B4GALT1	ENSSHAP00000020087	ENSSHAP00000009521	Mannosyltransferase.	Uncharacterized protein.	0.432
ALG12	DAD1	ENSSHAP00000020087	ENSSHAP00000012080	Mannosyltransferase.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.481
ALG12	DDOST	ENSSHAP00000020087	ENSSHAP00000009396	Mannosyltransferase.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.645