STRINGSTRING
CHUK CHUK ACSL4 ACSL4 MAPK10 MAPK10 PPARA PPARA NFKBIA NFKBIA PRKAG1 PRKAG1 CPT1A CPT1A CPT1B CPT1B TNF TNF MAPK9 MAPK9 PRKAG2 PRKAG2 RXRB RXRB PTPN11 PTPN11 STK11 STK11 NFKB1 NFKB1 TRAF2 TRAF2 ACSL6 ACSL6 SLC2A4 SLC2A4 ACSL1 ACSL1 CD36 CD36 ACSBG2 ACSBG2 PRKAA2 PRKAA2 G3W4A3_SARHA G3W4A3_SARHA AKT1 AKT1 TNFRSF1B TNFRSF1B NPY NPY PPARGC1A PPARGC1A ACACB ACACB LEPR LEPR ADIPOR2 ADIPOR2 IRS4 IRS4 ADIPOQ ADIPOQ PCK1 PCK1 AGRP AGRP PRKCQ PRKCQ PRKAA1 PRKAA1 IRS1 IRS1 ACSL3 ACSL3 STAT3 STAT3 JAK2 JAK2 G6PC3 G6PC3 SLC2A1 SLC2A1 PRKAG3 PRKAG3 RXRG RXRG RXRA RXRA ADIPOR1 ADIPOR1 CAMKK2 CAMKK2 PCK2 PCK2 ACSL5 ACSL5 LEP LEP PRKAB2 PRKAB2 MAPK8 MAPK8 IKBKB IKBKB SOCS3 SOCS3 ACSBG1 ACSBG1 PRKAB1 PRKAB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (738 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (722 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PPARAPeroxisome proliferator activated receptor alpha. (470 aa)
NFKBIAANK_REP_REGION domain-containing protein. (321 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (327 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (775 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (774 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
MAPK9Mitogen-activated protein kinase. (429 aa)
PRKAG2Uncharacterized protein. (283 aa)
RXRBRetinoid X receptor beta. (480 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
STK11Serine/threonine kinase 11. (252 aa)
NFKB1Nuclear factor kappa B subunit 1. (980 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
ACSL6AMP-binding domain-containing protein. (697 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (699 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
ACSBG2AMP-binding domain-containing protein. (650 aa)
PRKAA2Non-specific serine/threonine protein kinase. (520 aa)
G3W4A3_SARHAAMP-binding domain-containing protein. (653 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TNFRSF1BUncharacterized protein. (479 aa)
NPYNeuropeptide Y. (97 aa)
PPARGC1APPARG coactivator 1 alpha. (826 aa)
ACACBAcetyl-CoA carboxylase beta. (2348 aa)
LEPRLeptin receptor. (1166 aa)
ADIPOR2Adiponectin receptor 2. (387 aa)
IRS4IRS-type PTB domain-containing protein. (870 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (245 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (624 aa)
AGRPAgouti domain-containing protein. (156 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (709 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
IRS1Insulin receptor substrate 1. (1234 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (718 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (350 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (486 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (470 aa)
RXRGRetinoid X receptor gamma. (467 aa)
RXRARetinoid X receptor alpha. (483 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2; Belongs to the protein kinase superfamily. (443 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
ACSL5AMP-binding domain-containing protein. (425 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (242 aa)
MAPK8Mitogen-activated protein kinase. (429 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
SOCS3Suppressor of cytokine signaling 3. (228 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (652 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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