STRINGSTRING
CALM1-2 CALM1-2 GUCY1B1 GUCY1B1 GUCY1A2 GUCY1A2 CAMK2D CAMK2D PIK3R5 PIK3R5 CD38 CD38 PLA2G4D PLA2G4D ADCY2 ADCY2 CALML4 CALML4 CCND1 CCND1 PPP3CA PPP3CA PLA2G4E PLA2G4E GNAI3 GNAI3 PRKAG1 PRKAG1 KCNJ3 KCNJ3 TRPM2 TRPM2 PPP3CB PPP3CB LOC100929426 LOC100929426 G3VMA8_SARHA G3VMA8_SARHA PLA2G4F PLA2G4F MYL6 MYL6 MYLK3 MYLK3 GUCY1A1 GUCY1A1 MYL6B MYL6B LOC100929360 LOC100929360 CALML3 CALML3 PPP1CA PPP1CA PRKAG2 PRKAG2 ADCY3 ADCY3 KCNJ2 KCNJ2 PPP3R1 PPP3R1 ITPR3 ITPR3 ADCY4 ADCY4 GNAI1 GNAI1 GNAO1 GNAO1 NFATC4 NFATC4 EEF2K EEF2K ADCY6 ADCY6 EEF2 EEF2 MAPK1 MAPK1 PIK3CG PIK3CG PRKCB PRKCB NPPA NPPA CACNG6 CACNG6 MYL9 MYL9 PRKAA2 PRKAA2 ADCY1 ADCY1 RYR3 RYR3 PPP1CB PPP1CB NFATC1 NFATC1 NOS3 NOS3 PRKACA PRKACA MAP2K2 MAP2K2 PRKCA PRKCA CAMK1G CAMK1G RYR2 RYR2 GNAQ GNAQ KCNJ9 KCNJ9 NFATC3 NFATC3 NPR1 NPR1 MEF2C MEF2C MAPK3 MAPK3 RAF1 RAF1 OXTR OXTR CACNG2 CACNG2 CACNA2D4 CACNA2D4 KCNJ6 KCNJ6 CDKN1A CDKN1A CACNG3 CACNG3 CACNG4 CACNG4 RGS2 RGS2 CACNG1 CACNG1 CACNA2D1 CACNA2D1 ADCY9 ADCY9 ITPR1 ITPR1 ACTB ACTB CAMK1D CAMK1D PLCB2 PLCB2 PPP1CC PPP1CC GNAS GNAS MAPK7 MAPK7 PPP1R12B PPP1R12B NPR2 NPR2 PRKAA1 PRKAA1 MAP2K5 MAP2K5 ROCK1 ROCK1 CAMK2B CAMK2B CACNA1C CACNA1C LOC100913731 LOC100913731 PRKAG3 PRKAG3 PLCB1 PLCB1 G3WT87_SARHA G3WT87_SARHA PTGS2 PTGS2 CAMKK2 CAMKK2 RHOA RHOA RCAN1 RCAN1 CACNA1D CACNA1D PLA2G4A PLA2G4A PRKAB2 PRKAB2 CAMK2A CAMK2A SRC SRC FOS FOS PRKAB1 PRKAB1 NFATC2 NFATC2 KCNJ5 KCNJ5 PPP3CC PPP3CC GNAI2 GNAI2 CACNA2D2 CACNA2D2 ADCY7 ADCY7 CACNB4 CACNB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALM1-2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (627 aa)
GUCY1A2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (396 aa)
CAMK2DCaMKII_AD domain-containing protein. (87 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (871 aa)
CD38Uncharacterized protein. (230 aa)
PLA2G4DPhospholipase A2. (790 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (850 aa)
CALML4Calmodulin like 4. (155 aa)
CCND1Cyclin_C domain-containing protein. (141 aa)
PPP3CASerine/threonine-protein phosphatase. (502 aa)
PLA2G4EPhospholipase A2. (819 aa)
GNAI3G protein subunit alpha i3. (323 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (327 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (330 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1518 aa)
PPP3CBSerine/threonine-protein phosphatase. (501 aa)
LOC100929426Uncharacterized protein. (200 aa)
G3VMA8_SARHAUncharacterized protein. (192 aa)
PLA2G4FPhospholipase A2. (845 aa)
MYL6Myosin light chain 6. (151 aa)
MYLK3Myosin light chain kinase 3. (810 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
MYL6BMyosin light chain 6B. (209 aa)
LOC100929360Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (150 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (336 aa)
PRKAG2Uncharacterized protein. (283 aa)
ADCY3Adenylate cyclase 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (870 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
PPP3R1Uncharacterized protein. (170 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2665 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
GNAI1G protein subunit alpha i1. (354 aa)
GNAO1G protein subunit alpha o1. (354 aa)
NFATC4Nuclear factor of activated T cells 4. (875 aa)
EEF2KEukaryotic elongation factor 2 kinase. (621 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1173 aa)
EEF2Eukaryotic translation elongation factor 2. (858 aa)
MAPK1Mitogen-activated protein kinase. (348 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1103 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
NPPANatriuretic peptide A. (144 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (256 aa)
MYL9Myosin light chain 9. (172 aa)
PRKAA2Non-specific serine/threonine protein kinase. (520 aa)
ADCY1AC_N domain-containing protein. (214 aa)
RYR3Ryanodine receptor 3. (4637 aa)
PPP1CBSerine/threonine-protein phosphatase. (268 aa)
NFATC1Nuclear factor of activated T cells 1. (950 aa)
NOS3Nitric oxide synthase 3. (1022 aa)
PRKACAUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (377 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (578 aa)
CAMK1GProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (482 aa)
RYR2Uncharacterized protein. (3999 aa)
GNAQG protein subunit alpha q. (359 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (411 aa)
NFATC3Nuclear factor of activated T cells 3. (1052 aa)
NPR1Guanylate cyclase. (1013 aa)
MEF2CMyocyte enhancer factor 2C. (467 aa)
MAPK3Mitogen-activated protein kinase. (375 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (647 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (387 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1084 aa)
KCNJ6Uncharacterized protein. (328 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (165 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (253 aa)
RGS2Regulator of G protein signaling 2. (213 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1085 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1358 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2696 aa)
ACTBActin beta. (375 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (298 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (336 aa)
GNASUncharacterized protein. (320 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (783 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (934 aa)
NPR2Guanylate cyclase. (1062 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
ROCK1Uncharacterized protein. (516 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (641 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2069 aa)
LOC100913731Uncharacterized protein; Belongs to the protein kinase superfamily. (352 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (470 aa)
PLCB1Phosphoinositide phospholipase C. (1041 aa)
G3WT87_SARHAGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (655 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (609 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2; Belongs to the protein kinase superfamily. (443 aa)
RHOAUncharacterized protein. (193 aa)
RCAN1Regulator of calcineurin 1. (261 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1211 aa)
PLA2G4APhospholipase A2. (755 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (242 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (488 aa)
SRCTyrosine-protein kinase. (533 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (450 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
NFATC2Nuclear factor of activated T cells 2. (703 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (421 aa)
PPP3CCSerine/threonine-protein phosphatase. (531 aa)
GNAI2G protein subunit alpha i2. (319 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1067 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1116 aa)
CACNB4GuKc domain-containing protein. (268 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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