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| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (231 aa) |
| | CALM1-2 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | ATP5PO | Uncharacterized protein. (213 aa) |
| | TXN2 | Thioredoxin domain-containing protein. (165 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (378 aa) |
| | NDUFB7 | Uncharacterized protein. (78 aa) |
| | SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | G3VDR7_SARHA | Uncharacterized protein. (453 aa) |
| | ATP5MC3 | ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (151 aa) |
| | NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (166 aa) |
| | ATP5F1D | ATP-synt_DE_N domain-containing protein. (127 aa) |
| | CAMK2D | CaMKII_AD domain-containing protein. (87 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa) |
| | ADORA2A | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (111 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (374 aa) |
| | G3VHY9_SARHA | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (72 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (530 aa) |
| | CALML4 | Calmodulin like 4. (155 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | NDUFA4L2 | NDUFA4 mitochondrial complex associated like 2. (87 aa) |
| | NDUFV2 | NADH:ubiquinone oxidoreductase core subunit V2. (249 aa) |
| | NDUFA11 | Uncharacterized protein. (141 aa) |
| | GNAI3 | G protein subunit alpha i3. (323 aa) |
| | UBE2L3 | Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (442 aa) |
| | NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (377 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa) |
| | NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa) |
| | MAOB | Amine oxidase. (438 aa) |
| | LOC100929360 | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (163 aa) |
| | LOC100919671 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (150 aa) |
| | COX4I1 | Cytochrome c oxidase subunit 4I1. (178 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (429 aa) |
| | PSMA2 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (233 aa) |
| | NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (437 aa) |
| | ATP5MC2 | ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (154 aa) |
| | PSMD9 | PDZ domain-containing protein. (234 aa) |
| | MAOA | Amine oxidase. (430 aa) |
| | CYC1 | Cytochrome c1. (285 aa) |
| | PRKN | Ubiquitin-like domain-containing protein. (54 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2665 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | MCU | Mitochondrial calcium uniporter. (312 aa) |
| | G3VWL7_SARHA | COX6C domain-containing protein. (76 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1081 aa) |
| | G3VXD6_SARHA | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | TUBB3 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (435 aa) |
| | MFN2 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (158 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (170 aa) |
| | DAXX | Death domain associated protein. (754 aa) |
| | KIF5A | Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (281 aa) |
| | GNAL | G protein subunit alpha L. (390 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | NDUFA7 | Uncharacterized protein. (115 aa) |
| | NDUFS8 | NADH:ubiquinone oxidoreductase core subunit S8. (216 aa) |
| | NDUFA1 | Uncharacterized protein. (73 aa) |
| | RYR3 | Ryanodine receptor 3. (4637 aa) |
| | HSPA5 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (656 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (348 aa) |
| | NDUFA5 | NADH:ubiquinone oxidoreductase subunit A5. (116 aa) |
| | COX6B1 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa) |
| | UBE2J2 | Ubiquitin conjugating enzyme E2 J2. (260 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (275 aa) |
| | PRKACA | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (159 aa) |
| | G3W651_SARHA | Uncharacterized protein; Belongs to the peptidase C14A family. (282 aa) |
| | NDUFS4 | NADH:ubiquinone oxidoreductase subunit S4. (216 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | G3W8I7_SARHA | Tubulin domain-containing protein; Belongs to the tubulin family. (426 aa) |
| | SLC18A1 | Solute carrier family 18 member A1. (524 aa) |
| | XBP1 | BZIP domain-containing protein. (308 aa) |
| | ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1255 aa) |
| | G3WCX7_SARHA | Uncharacterized protein. (110 aa) |
| | NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa) |
| | UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (480 aa) |
| | NDUFB4 | Uncharacterized protein. (187 aa) |
| | SEPTIN5 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (400 aa) |
| | LOC100915370 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa) |
| | COX7A2L | Cytochrome c oxidase subunit 7A2 like. (132 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (293 aa) |
| | KLC4 | Kinesin light chain 4. (610 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (355 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2696 aa) |
| | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. (138 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1385 aa) |
| | UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) |
| | ATP5F1E | ATP synthase F1 subunit epsilon. (51 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) |
| | NDUFC2 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (105 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (407 aa) |
| | ATP5PB | ATP synthase peripheral stalk-membrane subunit b. (260 aa) |
| | LOC100932522 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (493 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (241 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (119 aa) |
| | GNAS | Uncharacterized protein. (320 aa) |
| | NDUFB3 | NADH:ubiquinone oxidoreductase subunit B3. (101 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | BCL2L1 | BCL2 like 1. (227 aa) |
| | UBE2J1 | Ubiquitin conjugating enzyme E2 J1. (320 aa) |
| | ATP5MC1 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (145 aa) |
| | NDUFS7 | NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (216 aa) |
| | COX4I2 | Cytochrome c oxidase subunit 4I2. (179 aa) |
| | NDUFB11 | NADH:ubiquinone oxidoreductase subunit B11. (152 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (379 aa) |
| | ATF4 | Activating transcription factor 4. (344 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (470 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (922 aa) |
| | TUBB2A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | COX6A2 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) |
| | SNCAIP | ANK_REP_REGION domain-containing protein. (494 aa) |
| | TRAP1 | TNF receptor associated protein 1. (466 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (454 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (641 aa) |
| | NDUFB10 | NADH:ubiquinone oxidoreductase subunit B10. (176 aa) |
| | LOC100913731 | Uncharacterized protein; Belongs to the protein kinase superfamily. (352 aa) |
| | NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) |
| | UBE2L6 | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | PSMA7 | Proteasome subunit alpha type. (251 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (371 aa) |
| | GPR37 | G protein-coupled receptor 37. (598 aa) |
| | KLC1 | Uncharacterized protein. (633 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | LOC100920562 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | PSMB1 | Proteasome subunit beta. (244 aa) |
| | UBA1 | UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1059 aa) |
| | NDUFB2 | NADH:ubiquinone oxidoreductase subunit B2. (102 aa) |
| | COX5A | Cytochrome c oxidase subunit 5A. (117 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | UCHL1 | Ubiquitin carboxyl-terminal hydrolase. (165 aa) |
| | SLC18A2 | Solute carrier family 18 member A2. (514 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa) |
| | LOC100919666 | Uncharacterized protein. (430 aa) |
| | MFN1 | Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (762 aa) |
| | SDHC | Succinate dehydrogenase complex subunit C. (169 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (445 aa) |
| | PSMA8 | Proteasome subunit alpha type. (257 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | NDUFB5 | NADH:ubiquinone oxidoreductase subunit B5. (149 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | COX5B | Cytochrome c oxidase subunit 5B. (128 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (488 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | NDUFS5 | NADH:ubiquinone oxidoreductase subunit S5. (106 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (298 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (429 aa) |
| | NDUFS3 | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (187 aa) |
| | NDUFS6 | NADH:ubiquinone oxidoreductase subunit S6. (153 aa) |
| | UBA7 | Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1023 aa) |
| | NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (298 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (598 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (671 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (414 aa) |
| | GNAI2 | G protein subunit alpha i2. (319 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) |
| | ND1 | NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa) |
| | MT-ND2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (345 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa) |
| | ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (69 aa) |
| | ATP6 | ATP synthase subunit a. (226 aa) |
| | COX3 | Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa) |
| | MT-ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa) |
| | ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa) |
| | MT-ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa) |
| | MT-ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (605 aa) |
| | ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (166 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (381 aa) |
