STRINGSTRING
PSMD8 PSMD8 SMCR8 SMCR8 ATP5PO ATP5PO PSMD7 PSMD7 NDUFB7 NDUFB7 DNAH8 DNAH8 DNAH6 DNAH6 G3VDR7_SARHA G3VDR7_SARHA NXT2 NXT2 ATP5MC3 ATP5MC3 NDUFA13 NDUFA13 NEFH NEFH DNAH11 DNAH11 ATP5F1D ATP5F1D NUP62 NUP62 DNAH1 DNAH1 GRIA2 GRIA2 PSMC4 PSMC4 G3VHY9_SARHA G3VHY9_SARHA DNAH9 DNAH9 ATP5F1B ATP5F1B PSMB6 PSMB6 NUP210 NUP210 NDUFA4L2 NDUFA4L2 G3VJK8_SARHA G3VJK8_SARHA GABARAPL2 GABARAPL2 NDUFV2 NDUFV2 C9orf72 C9orf72 ULK2 ULK2 NDUFA11 NDUFA11 PPP3CA PPP3CA MSS51 MSS51 SLC1A2 SLC1A2 RAB1A RAB1A DCTN5 DCTN5 PPP3CB PPP3CB GPX7 GPX7 RAB39B RAB39B TNF TNF PSMC2 PSMC2 SOD1 SOD1 NDUFA9 NDUFA9 PSMD1 PSMD1 NUP37 NUP37 LOC100930529 LOC100930529 GPX8 GPX8 RANBP2 RANBP2 NDUFA10 NDUFA10 NRBF2 NRBF2 NUP54 NUP54 LOC100919671 LOC100919671 PRPH PRPH COX4I1 COX4I1 PSMA2 PSMA2 NDUFV1 NDUFV1 MAPK13 MAPK13 ATP5MC2 ATP5MC2 PSMD9 PSMD9 PFN1 PFN1 CYC1 CYC1 PRKN PRKN PPP3R1 PPP3R1 KIF5B KIF5B FIG4 FIG4 ITPR3 ITPR3 NUP50 NUP50 TBK1 TBK1 RNASE4 RNASE4 MCU MCU NXF1 NXF1 ANG ANG RAB8A RAB8A NDC1 NDC1 DNAH3 DNAH3 G3VWL7_SARHA G3VWL7_SARHA NEFM NEFM EIF2AK3 EIF2AK3 RAB5A RAB5A G3VXD6_SARHA G3VXD6_SARHA TUBB6 TUBB6 TUBB3 TUBB3 LOC100913862 LOC100913862 WIPI2 WIPI2 ATXN2 ATXN2 DDIT3 DDIT3 GABARAPL1 GABARAPL1 DAXX DAXX DCTN2 DCTN2 TRAF2 TRAF2 FBXO21 FBXO21 CAT CAT KIF5A KIF5A SDHB SDHB TUBB TUBB TUBB4B TUBB4B NDUFA7 NDUFA7 GABARAP GABARAP NDUFS8 NDUFS8 PIK3R4 PIK3R4 LOC100915932 LOC100915932 CHMP2B CHMP2B GRIN2A GRIN2A RB1CC1 RB1CC1 ATG14 ATG14 DNAL1 DNAL1 NDUFA1 NDUFA1 NOS2 NOS2 HSPA5 HSPA5 NUP98 NUP98 PSMD13 PSMD13 NDUFA5 NDUFA5 COX6B1 COX6B1 WIPI1 WIPI1 TNFRSF1B TNFRSF1B CASP3 CASP3 BID BID NDUFAB1 NDUFAB1 G3W651_SARHA G3W651_SARHA GRIN1 GRIN1 NUP35 NUP35 NDUFS4 NDUFS4 EIF2S1 EIF2S1 HNRNPA1 HNRNPA1 G3W8I7_SARHA G3W8I7_SARHA SQSTM1 SQSTM1 MATR3 MATR3 ALYREF ALYREF DNAH14 DNAH14 G3WA46_SARHA G3WA46_SARHA XBP1 XBP1 NUP107 NUP107 SRSF3 SRSF3 ATP5PF ATP5PF APAF1 APAF1 GRIN2B GRIN2B G3WCX7_SARHA G3WCX7_SARHA NDUFA8 NDUFA8 UQCRC1 UQCRC1 DCTN6 DCTN6 NDUFB4 NDUFB4 NUP93 NUP93 NUP210L NUP210L COX7A2L COX7A2L KLC4 KLC4 TUBA8 TUBA8 DNALI1 DNALI1 PSMD6 PSMD6 ACTB ACTB NDUFA6 NDUFA6 ATG101 ATG101 MAP3K5 MAP3K5 BECN1 BECN1 UQCRQ UQCRQ ATP5F1E ATP5F1E TUBB1 TUBB1 NDUFC2 NDUFC2 PSMC5 PSMC5 GPX2 GPX2 ATP5PB ATP5PB UBQLN4 UBQLN4 LOC100932522 LOC100932522 TUBA4A TUBA4A DNAH7 DNAH7 ULK1 ULK1 NDUFA12 NDUFA12 NDUFB3 NDUFB3 G3WKD7_SARHA G3WKD7_SARHA PSMB5 PSMB5 UBQLN3 UBQLN3 BCL2L1 BCL2L1 NRG2 NRG2 ATP5MC1 ATP5MC1 NDUFS7 NDUFS7 COX4I2 COX4I2 NDUFB11 NDUFB11 TARDBP TARDBP PSMD4 PSMD4 ATF4 ATF4 ERBB4 ERBB4 PSMD3 PSMD3 NUP133 NUP133 ERN1 ERN1 TUBB2A TUBB2A COX6A2 COX6A2 MAP2K3 MAP2K3 NUP205 NUP205 ALS2 ALS2 OPTN OPTN PSMB4 PSMB4 G3WPM9_SARHA G3WPM9_SARHA DNAH2 DNAH2 NDUFB10 NDUFB10 TPR TPR NDUFB8 NDUFB8 PSMA7 PSMA7 TP53 TP53 KLC1 KLC1 DNAL4 DNAL4 PSMA1 PSMA1 LOC100920562 LOC100920562 AMBRA1 AMBRA1 PSMB1 PSMB1 TANK TANK NDUFB2 NDUFB2 COX5A COX5A SRSF7 SRSF7 PSMB7 PSMB7 NUP153 NUP153 VAPB VAPB DNAH10 DNAH10 GPX1 GPX1 ATG13 ATG13 PSMD14 PSMD14 SEC13 SEC13 NRG1 NRG1 NDUFS2 NDUFS2 VCP VCP LOC100919666 LOC100919666 TOMM40L TOMM40L SPG11 SPG11 SDHC SDHC PSMC1 PSMC1 PSMA8 PSMA8 DCTN1 DCTN1 ATP5F1A ATP5F1A NUP214 NUP214 DNAH12 DNAH12 NDUFB5 NDUFB5 ACTR1B ACTR1B PSMB3 PSMB3 COX5B COX5B SIGMAR1 SIGMAR1 PSMA4 PSMA4 NUP43 NUP43 DCTN3 DCTN3 NDUFS5 NDUFS5 VDAC1 VDAC1 DNAH17 DNAH17 NDUFS3 NDUFS3 NUP155 NUP155 DCTN4 DCTN4 DNAI1 DNAI1 NDUFS6 NDUFS6 BCL2 BCL2 NUP160 NUP160 NDUFS1 NDUFS1 ACTR10 ACTR10 PSMA3 PSMA3 ATP5F1C ATP5F1C PSMA5 PSMA5 WDR41 WDR41 HNRNPA3 HNRNPA3 SDHA SDHA PPP3CC PPP3CC PSMD11 PSMD11 NUP85 NUP85 SETX SETX ATP5PD ATP5PD ACTR1A ACTR1A PFN2 PFN2 NUP188 NUP188 ND1 ND1 MT-ND2 MT-ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 MT-ND3 MT-ND3 ND4L ND4L MT-ND4 MT-ND4 MT-ND5 MT-ND5 ND6 ND6 CYTB CYTB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PSMD8Proteasome 26S subunit, non-ATPase 8. (231 aa)
SMCR8SMCR8-C9orf72 complex subunit. (934 aa)
ATP5POUncharacterized protein. (213 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (378 aa)
NDUFB7Uncharacterized protein. (78 aa)
DNAH8Uncharacterized protein. (2789 aa)
DNAH6Uncharacterized protein. (832 aa)
G3VDR7_SARHAUncharacterized protein. (453 aa)
NXT2NTF2 domain-containing protein. (90 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (151 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (166 aa)
NEFHNeurofilament heavy; Belongs to the intermediate filament family. (773 aa)
DNAH11Uncharacterized protein. (905 aa)
ATP5F1DATP-synt_DE_N domain-containing protein. (127 aa)
NUP62Nsp1_C domain-containing protein. (607 aa)
DNAH1Uncharacterized protein. (1351 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (852 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (374 aa)
G3VHY9_SARHACytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (72 aa)
DNAH9DHC_N1 domain-containing protein. (402 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (530 aa)
PSMB6Proteasome subunit beta. (239 aa)
NUP210Uncharacterized protein. (217 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (87 aa)
G3VJK8_SARHANTF2 domain-containing protein. (143 aa)
GABARAPL2GABA type A receptor associated protein like 2. (119 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1010 aa)
NDUFA11Uncharacterized protein. (141 aa)
PPP3CASerine/threonine-protein phosphatase. (502 aa)
MSS51MSS51 mitochondrial translational activator. (449 aa)
SLC1A2Amino acid transporter. (568 aa)
RAB1ARAB1A, member RAS oncogene family. (221 aa)
DCTN5Dynactin subunit 5. (187 aa)
PPP3CBSerine/threonine-protein phosphatase. (501 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
RAB39BRAB39B, member RAS oncogene family. (144 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (442 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (156 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
NUP37Nucleoporin 37. (326 aa)
LOC100930529Uncharacterized protein. (235 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
RANBP2RAN binding protein 2. (2975 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
NRBF2Nuclear receptor binding factor 2. (280 aa)
NUP54Nucleoporin 54. (506 aa)
LOC100919671Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
PRPHPeripherin; Belongs to the intermediate filament family. (472 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (178 aa)
PSMA2Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (233 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (437 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
ATP5MC2ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (154 aa)
PSMD9PDZ domain-containing protein. (234 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
CYC1Cytochrome c1. (285 aa)
PRKNUbiquitin-like domain-containing protein. (54 aa)
PPP3R1Uncharacterized protein. (170 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (906 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2665 aa)
NUP50Nucleoporin 50. (425 aa)
TBK1TANK binding kinase 1. (732 aa)
RNASE4Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (142 aa)
MCUMitochondrial calcium uniporter. (312 aa)
NXF1Uncharacterized protein. (624 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (153 aa)
RAB8ARAB8A, member RAS oncogene family. (208 aa)
NDC1NDC1 transmembrane nucleoporin. (590 aa)
DNAH3AAA domain-containing protein. (2378 aa)
G3VWL7_SARHACOX6C domain-containing protein. (76 aa)
NEFMIF rod domain-containing protein; Belongs to the intermediate filament family. (519 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1081 aa)
RAB5ARAB5A, member RAS oncogene family. (216 aa)
G3VXD6_SARHATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (435 aa)
LOC100913862Uncharacterized protein; Belongs to the peptidase C14A family. (423 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (411 aa)
ATXN2Ataxin 2. (1075 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (170 aa)
GABARAPL1Uncharacterized protein. (136 aa)
DAXXDeath domain associated protein. (754 aa)
DCTN2Dynactin subunit 2. (410 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
FBXO21F-box protein 21. (542 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (281 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
NDUFA7Uncharacterized protein. (115 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (216 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1363 aa)
LOC100915932Uncharacterized protein. (220 aa)
CHMP2BCharged multivesicular body protein 2B. (212 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1333 aa)
RB1CC1RB1 inducible coiled-coil 1. (1592 aa)
ATG14Autophagy related 14. (511 aa)
DNAL1Dynein axonemal light chain 1. (190 aa)
NDUFA1Uncharacterized protein. (73 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (656 aa)
NUP98Nucleoporin 98. (1816 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (348 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (458 aa)
TNFRSF1BUncharacterized protein. (479 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (275 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (159 aa)
G3W651_SARHAUncharacterized protein; Belongs to the peptidase C14A family. (282 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (933 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (216 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
HNRNPA1Uncharacterized protein. (372 aa)
G3W8I7_SARHATubulin domain-containing protein; Belongs to the tubulin family. (426 aa)
SQSTM1Sequestosome 1. (401 aa)
MATR3Uncharacterized protein. (857 aa)
ALYREFAly/REF export factor. (193 aa)
DNAH14MT domain-containing protein. (257 aa)
G3WA46_SARHANTF2 domain-containing protein. (142 aa)
XBP1BZIP domain-containing protein. (308 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (932 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1255 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1118 aa)
G3WCX7_SARHAUncharacterized protein. (110 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
DCTN6Dynactin subunit 6. (188 aa)
NDUFB4Uncharacterized protein. (187 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (822 aa)
NUP210LNucleoporin 210 like. (1810 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (132 aa)
KLC4Kinesin light chain 4. (610 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
DNALI1Dynein axonemal light intermediate chain 1. (259 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (355 aa)
ACTBActin beta. (375 aa)
NDUFA6NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. (138 aa)
ATG101Autophagy related 101. (218 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1385 aa)
BECN1Beclin 1. (448 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (105 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (407 aa)
GPX2Glutathione peroxidase 2. (180 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (260 aa)
UBQLN4Ubiquilin 4. (582 aa)
LOC100932522Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (493 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
DNAH7EF-hand domain-containing protein. (3446 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1063 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (119 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (101 aa)
G3WKD7_SARHAUncharacterized protein. (347 aa)
PSMB5Proteasome subunit beta. (263 aa)
UBQLN3Ubiquilin 3. (676 aa)
BCL2L1BCL2 like 1. (227 aa)
NRG2Neuregulin 2. (716 aa)
ATP5MC1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (145 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (216 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (179 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (152 aa)
TARDBPTAR DNA binding protein. (414 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (379 aa)
ATF4Activating transcription factor 4. (344 aa)
ERBB4Uncharacterized protein. (596 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (470 aa)
NUP133Nucleoporin 133. (1136 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (922 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (337 aa)
NUP205Nucleoporin 205. (2014 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1662 aa)
OPTNOptineurin. (374 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
G3WPM9_SARHANsp1_C domain-containing protein. (266 aa)
DNAH2Dynein axonemal heavy chain 2. (4431 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
TPRTranslocated promoter region, nuclear basket protein. (2345 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
PSMA7Proteasome subunit alpha type. (251 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (371 aa)
KLC1Uncharacterized protein. (633 aa)
DNAL4Dynein light chain. (104 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
LOC100920562Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1290 aa)
PSMB1Proteasome subunit beta. (244 aa)
TANKTRAF family member associated NFKB activator. (446 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (102 aa)
COX5ACytochrome c oxidase subunit 5A. (117 aa)
SRSF7Uncharacterized protein. (236 aa)
PSMB7Proteasome subunit beta. (277 aa)
NUP153Uncharacterized protein. (938 aa)
VAPBVAMP associated protein B and C. (240 aa)
DNAH10Dynein axonemal heavy chain 10. (4380 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
NRG1Neuregulin 1. (710 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (802 aa)
LOC100919666Uncharacterized protein. (430 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (308 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2200 aa)
SDHCSuccinate dehydrogenase complex subunit C. (169 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (445 aa)
PSMA8Proteasome subunit alpha type. (257 aa)
DCTN1CAP-Gly domain-containing protein. (1283 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
NUP214Nucleoporin 214. (2141 aa)
DNAH12Uncharacterized protein. (3669 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (149 aa)
ACTR1BActin related protein 1B. (373 aa)
PSMB3Proteasome subunit beta. (205 aa)
COX5BCytochrome c oxidase subunit 5B. (128 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
NUP43Nucleoporin 43. (381 aa)
DCTN3Dynactin subunit 3. (186 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
VDAC1Voltage dependent anion channel 1. (298 aa)
DNAH17Uncharacterized protein. (2258 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (187 aa)
NUP155Nucleoporin 155. (1397 aa)
DCTN4Dynactin subunit 4. (470 aa)
DNAI1Dynein axonemal intermediate chain 1. (706 aa)
NDUFS6NADH:ubiquinone oxidoreductase subunit S6. (153 aa)
BCL2BCL2 apoptosis regulator. (227 aa)
NUP160Nucleoporin 160. (1362 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (417 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
WDR41WD repeat domain 41. (459 aa)
HNRNPA3Heterogeneous nuclear ribonucleoprotein A3. (324 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (671 aa)
PPP3CCSerine/threonine-protein phosphatase. (531 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (414 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (705 aa)
SETXSenataxin. (2763 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
ACTR1AActin related protein 1A. (376 aa)
PFN2Profilin; Belongs to the profilin family. (110 aa)
NUP188Nucleoporin 188. (1736 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
MT-ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (345 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (69 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
MT-ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
MT-ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
MT-ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (605 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (166 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (381 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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