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CALM1-2 CALM1-2 G3VBV2_SARHA G3VBV2_SARHA SHC3 SHC3 LOC100916825 LOC100916825 G3VG54_SARHA G3VG54_SARHA GNG8 GNG8 GNG12 GNG12 ADORA2A ADORA2A HDAC7 HDAC7 CALML4 CALML4 LOC100924763 LOC100924763 LOC100914215 LOC100914215 LOC100913958 LOC100913958 LOC100913692 LOC100913692 GNAI3 GNAI3 SOS2 SOS2 LOC100929420 LOC100929420 LOC100929426 LOC100929426 G3VMA8_SARHA G3VMA8_SARHA LOC100929673 LOC100929673 GNGT1 GNGT1 LOC100928127 LOC100928127 H2AC1 H2AC1 LOC100920799 LOC100920799 SHC1 SHC1 MAOB MAOB HDAC11 HDAC11 LOC100929360 LOC100929360 CALML3 CALML3 G3VSY4_SARHA G3VSY4_SARHA PPP1CA PPP1CA G3VT75_SARHA G3VT75_SARHA LOC100918642 LOC100918642 MAOA MAOA G3VUC4_SARHA G3VUC4_SARHA LOC100924731 LOC100924731 G3VUY6_SARHA G3VUY6_SARHA ARAF ARAF GNAI1 GNAI1 G3VVW9_SARHA G3VVW9_SARHA GNAO1 GNAO1 MAPK1 MAPK1 MACROH2A2 MACROH2A2 GRIN2A GRIN2A GNB2 GNB2 PPP1CB PPP1CB NPY NPY PRKACA PRKACA SLC29A3 SLC29A3 GRIN1 GRIN1 CREB3L3 CREB3L3 ATF6B ATF6B H2AX H2AX HDAC1 HDAC1 SLC18A1 SLC18A1 GRIN3A GRIN3A MAPK3 MAPK3 ATF2 ATF2 HDAC3 HDAC3 RAF1 RAF1 GRIN2B GRIN2B SHC2 SHC2 CREB3L2 CREB3L2 PKIA PKIA CREB3L4 CREB3L4 CREB5 CREB5 GNB1 GNB1 HDAC2 HDAC2 PDYN PDYN CRH CRH PPP1CC PPP1CC GNAS GNAS GNG13 GNG13 CREB1 CREB1 ATF4 ATF4 CREB3 CREB3 NTRK2 NTRK2 BDNF BDNF DRD2 DRD2 SOS1 SOS1 HDAC5 HDAC5 HDAC8 HDAC8 LOC100913731 LOC100913731 CREB3L1 CREB3L1 SHC4 SHC4 HAT1 HAT1 GNB3 GNB3 CAMKK2 CAMKK2 SLC6A3 SLC6A3 DDC DDC SLC18A2 SLC18A2 G3WWR9_SARHA G3WWR9_SARHA GNB4 GNB4 H2AZ2 H2AZ2 GNB5 GNB5 SLC29A1 SLC29A1 GNG5 GNG5 GRB2 GRB2 GNAI2 GNAI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALM1-2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
G3VBV2_SARHAHistone H3; Belongs to the histone H3 family. (142 aa)
SHC3SHC adaptor protein 3. (422 aa)
LOC100916825Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
G3VG54_SARHAHistone H2A; Belongs to the histone H2A family. (137 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADORA2AG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (111 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1002 aa)
CALML4Calmodulin like 4. (155 aa)
LOC100924763Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC100914215Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC100913958Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100913692Histone H2B; Belongs to the histone H2B family. (126 aa)
GNAI3G protein subunit alpha i3. (323 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1329 aa)
LOC100929420Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC100929426Uncharacterized protein. (200 aa)
G3VMA8_SARHAUncharacterized protein. (192 aa)
LOC100929673Histone H2B; Belongs to the histone H2B family. (126 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
LOC100928127Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC1Histone H2A; Belongs to the histone H2A family. (132 aa)
LOC100920799Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
SHC1SHC adaptor protein 1. (569 aa)
MAOBAmine oxidase. (438 aa)
HDAC11Histone deacetylase 11. (325 aa)
LOC100929360Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (150 aa)
G3VSY4_SARHAHistone H2A; Belongs to the histone H2A family. (137 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (336 aa)
G3VT75_SARHAHistone H2B; Belongs to the histone H2B family. (134 aa)
LOC100918642Histone H3; Belongs to the histone H3 family. (136 aa)
MAOAAmine oxidase. (430 aa)
G3VUC4_SARHAHistone H2A; Belongs to the histone H2A family. (108 aa)
LOC100924731Histone H2A; Belongs to the histone H2A family. (143 aa)
G3VUY6_SARHAHistone H2A; Belongs to the histone H2A family. (142 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (627 aa)
GNAI1G protein subunit alpha i1. (354 aa)
G3VVW9_SARHAHistone H2A; Belongs to the histone H2A family. (131 aa)
GNAO1G protein subunit alpha o1. (354 aa)
MAPK1Mitogen-activated protein kinase. (348 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1333 aa)
GNB2G protein subunit beta 2. (340 aa)
PPP1CBSerine/threonine-protein phosphatase. (268 aa)
NPYNeuropeptide Y. (97 aa)
PRKACAUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
SLC29A3Solute carrier family 29 member 3. (477 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (933 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (465 aa)
ATF6BActivating transcription factor 6 beta. (709 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (145 aa)
HDAC1Hist_deacetyl domain-containing protein. (323 aa)
SLC18A1Solute carrier family 18 member A1. (524 aa)
GRIN3AUncharacterized protein. (1055 aa)
MAPK3Mitogen-activated protein kinase. (375 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (503 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (647 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1118 aa)
SHC2Uncharacterized protein. (479 aa)
CREB3L2BZIP domain-containing protein. (517 aa)
PKIAcAMP-dependent protein kinase inhibitor alpha. (75 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (389 aa)
CREB5Uncharacterized protein. (109 aa)
GNB1G protein subunit beta 1. (340 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (473 aa)
PDYNProdynorphin. (258 aa)
CRHCorticotropin releasing hormone. (200 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (336 aa)
GNASUncharacterized protein. (320 aa)
GNG13G protein subunit gamma 13. (67 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
ATF4Activating transcription factor 4. (344 aa)
CREB3BZIP domain-containing protein. (370 aa)
NTRK2Ig-like domain-containing protein. (310 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (246 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (454 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1325 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (979 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (379 aa)
LOC100913731Uncharacterized protein; Belongs to the protein kinase superfamily. (352 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (526 aa)
SHC4SHC adaptor protein 4. (538 aa)
HAT1Histone acetyltransferase 1. (366 aa)
GNB3G protein subunit beta 3. (340 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2; Belongs to the protein kinase superfamily. (443 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
DDCDopa decarboxylase. (485 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
G3WWR9_SARHAHistone H2A; Belongs to the histone H2A family. (130 aa)
GNB4G protein subunit beta 4. (340 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
GNB5G protein subunit beta 5. (395 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (454 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRB2Growth factor receptor bound protein 2. (191 aa)
GNAI2G protein subunit alpha i2. (319 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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