Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABL1 | ATM | ENSSHAP00000019280 | ENSSHAP00000012661 | Tyrosine-protein kinase. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.751 |
| ABL1 | BRCA1 | ENSSHAP00000019280 | ENSSHAP00000013295 | Tyrosine-protein kinase. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.542 |
| ABL1 | CDKN1A | ENSSHAP00000019280 | ENSSHAP00000013540 | Tyrosine-protein kinase. | Cyclin dependent kinase inhibitor 1A. | 0.425 |
| ABL1 | CDKN1B | ENSSHAP00000019280 | ENSSHAP00000013483 | Tyrosine-protein kinase. | Cyclin dependent kinase inhibitor 1B. | 0.425 |
| ABL1 | CRKL | ENSSHAP00000019280 | ENSSHAP00000001508 | Tyrosine-protein kinase. | CRK like proto-oncogene, adaptor protein. | 0.972 |
| ABL1 | GRB2 | ENSSHAP00000019280 | ENSSHAP00000021710 | Tyrosine-protein kinase. | Growth factor receptor bound protein 2. | 0.963 |
| ABL1 | SHC1 | ENSSHAP00000019280 | ENSSHAP00000005170 | Tyrosine-protein kinase. | SHC adaptor protein 1. | 0.927 |
| ABL1 | SHC4 | ENSSHAP00000019280 | ENSSHAP00000018142 | Tyrosine-protein kinase. | SHC adaptor protein 4. | 0.920 |
| ABL1 | STAT3 | ENSSHAP00000019280 | ENSSHAP00000017457 | Tyrosine-protein kinase. | Signal transducer and activator of transcription. | 0.453 |
| ABL1 | TP53 | ENSSHAP00000019280 | ENSSHAP00000018268 | Tyrosine-protein kinase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.401 |
| APC | APC2 | ENSSHAP00000001270 | ENSSHAP00000015380 | Uncharacterized protein. | APC regulator of WNT signaling pathway 2. | 0.902 |
| APC | CASP3 | ENSSHAP00000001270 | ENSSHAP00000010635 | Uncharacterized protein. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.484 |
| APC | G3W651_SARHA | ENSSHAP00000001270 | ENSSHAP00000010906 | Uncharacterized protein. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.484 |
| APC2 | APC | ENSSHAP00000015380 | ENSSHAP00000001270 | APC regulator of WNT signaling pathway 2. | Uncharacterized protein. | 0.902 |
| APC2 | CASP3 | ENSSHAP00000015380 | ENSSHAP00000010635 | APC regulator of WNT signaling pathway 2. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.438 |
| APC2 | G3W651_SARHA | ENSSHAP00000015380 | ENSSHAP00000010906 | APC regulator of WNT signaling pathway 2. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.438 |
| ATM | ABL1 | ENSSHAP00000012661 | ENSSHAP00000019280 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Tyrosine-protein kinase. | 0.751 |
| ATM | BCL2 | ENSSHAP00000012661 | ENSSHAP00000020974 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | BCL2 apoptosis regulator. | 0.405 |
| ATM | BRCA1 | ENSSHAP00000012661 | ENSSHAP00000013295 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.995 |
| ATM | CASP3 | ENSSHAP00000012661 | ENSSHAP00000010635 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.474 |
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