STRINGSTRING
ITGA2 ITGA2 ITGB8 ITGB8 ITGB7 ITGB7 SLC8A1 SLC8A1 PRKAG1 PRKAG1 TNF TNF TPM4 TPM4 PRKAG2 PRKAG2 TGFB1 TGFB1 MYL3 MYL3 SGCG SGCG IGF1 IGF1 CACNG6 CACNG6 PRKAA2 PRKAA2 ITGAV ITGAV TNNC1 TNNC1 ITGA7 ITGA7 RYR2 RYR2 LAMA1 LAMA1 TTN TTN ACE ACE ITGB6 ITGB6 LOC100932800 LOC100932800 ITGA5 ITGA5 IL6 IL6 CACNG2 CACNG2 CACNA2D4 CACNA2D4 ITGA1 ITGA1 CACNG3 CACNG3 CACNG4 CACNG4 ITGA9 ITGA9 DMD DMD ATP2A1 ATP2A1 CACNG1 CACNG1 CACNA2D1 CACNA2D1 MYL2 MYL2 DES DES ITGA3 ITGA3 ACTB ACTB TPM3 TPM3 SGCD SGCD ITGA8 ITGA8 SGCA SGCA LMNA LMNA ITGA4 ITGA4 PRKAA1 PRKAA1 TPM2 TPM2 MYH7 MYH7 EDN1 EDN1 CACNA1C CACNA1C PRKAG3 PRKAG3 LAMA2 LAMA2 ITGA2B ITGA2B ITGB1 ITGB1 CACNA1D CACNA1D ACTC1 ACTC1 DAG1 DAG1 TPM1 TPM1 PRKAB2 PRKAB2 ITGA6 ITGA6 TGFB2 TGFB2 AGT AGT SGCB SGCB ITGB3 ITGB3 PRKAB1 PRKAB1 ITGA10 ITGA10 CACNA2D2 CACNA2D2 CACNB4 CACNB4 SLC8A3 SLC8A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA2Integrin_alpha2 domain-containing protein. (326 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (726 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (808 aa)
SLC8A1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (601 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (327 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
TPM4Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
PRKAG2Uncharacterized protein. (283 aa)
TGFB1TGF_BETA_2 domain-containing protein. (162 aa)
MYL3Myosin light chain 3. (195 aa)
SGCGUncharacterized protein. (106 aa)
IGF1Insulin like growth factor 1. (130 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (256 aa)
PRKAA2Non-specific serine/threonine protein kinase. (520 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1013 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (169 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1169 aa)
RYR2Uncharacterized protein. (3999 aa)
LAMA1Laminin subunit alpha 1. (3074 aa)
TTNUncharacterized protein. (29761 aa)
ACEAngiotensin-converting enzyme. (1304 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
LOC100932800Angiotensin-converting enzyme. (733 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1061 aa)
IL6Uncharacterized protein. (212 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1084 aa)
ITGA1Uncharacterized protein. (159 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (253 aa)
ITGA9Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (494 aa)
DMDUncharacterized protein. (1554 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1085 aa)
MYL2Myosin light chain 2. (171 aa)
DESDesmin; Belongs to the intermediate filament family. (472 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1051 aa)
ACTBActin beta. (375 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (284 aa)
SGCDSarcoglycan delta. (224 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (997 aa)
SGCASarcoglycan alpha. (387 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (527 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (325 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
EDN1Endothelin 1. (214 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2069 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (470 aa)
LAMA2Laminin subunit alpha 2. (3062 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1057 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (799 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1211 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
DAG1Dystroglycan 1. (895 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (242 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1080 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
AGTSERPIN domain-containing protein; Belongs to the serpin family. (484 aa)
SGCBSarcoglycan beta. (320 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1166 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1067 aa)
CACNB4GuKc domain-containing protein. (268 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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