STRINGSTRING
ABD29345.1 ABD29345.1 ABD29346.1 ABD29346.1 ABD29347.1 ABD29347.1 ABD29348.1 ABD29348.1 ABD29350.1 ABD29350.1 azoR azoR ABD29352.1 ABD29352.1 ABD29353.1 ABD29353.1 ABD29354.1 ABD29354.1 ABD29355.1 ABD29355.1 ABD29356.1 ABD29356.1 ABD29357.1 ABD29357.1 ABD29358.1 ABD29358.1 ABD29359.1 ABD29359.1 nikA nikA ABD29671.1 ABD29671.1 ABD29769.1 ABD29769.1 ABD29770.1 ABD29770.1 ABD29771.1 ABD29771.1 ABD29772.1 ABD29772.1 ABD29773.1 ABD29773.1 ABD30047.1 ABD30047.1 ABD30048.1 ABD30048.1 ABD30049.1 ABD30049.1 ABD30050.1 ABD30050.1 ABD30051.1 ABD30051.1 ABD30052.1 ABD30052.1 ABD30053.1 ABD30053.1 ABD30054.1 ABD30054.1 ABD30055.1 ABD30055.1 ABD30056.1 ABD30056.1 ABD30057.1 ABD30057.1 ABD30141.1 ABD30141.1 ABD30142.1 ABD30142.1 ABD30143.1 ABD30143.1 ABD30144.1 ABD30144.1 mntH mntH ABD30173.1 ABD30173.1 ABD30174.1 ABD30174.1 ABD30175.1 ABD30175.1 ABD30176.1 ABD30176.1 ABD30471.1 ABD30471.1 nikE nikE nikD nikD nikC nikC nikB nikB ABD30476.1 ABD30476.1 ABD30477.1 ABD30477.1 ABD30478.1 ABD30478.1 xerD xerD ABD30671.1 ABD30671.1 ABD30673.1 ABD30673.1 fur fur ABD30731.1 ABD30731.1 ABD30732.1 ABD30732.1 nfo nfo cshB cshB ABD30735.1 ABD30735.1 ABD30736.1 ABD30736.1 sigA sigA dnaG dnaG ABD30739.1 ABD30739.1 ABD30740.1 ABD30740.1 ABD31484.1 ABD31484.1 truA truA ecfT ecfT ecfA2 ecfA2 ecfA1 ecfA1 ABD31565.1 ABD31565.1 ABD31594.1 ABD31594.1 ABD31595.1 ABD31595.1 ABD31698.1 ABD31698.1 ABD31766.1 ABD31766.1 cntF cntF cntD cntD cntC cntC cntB cntB cntA cntA ABD31772.1 ABD31772.1 ABD31773.1 ABD31773.1 ABD31774.1 ABD31774.1 ABD31820.1 ABD31820.1 ABD31821.1 ABD31821.1 ABD31834.1 ABD31834.1 ABD31835.1 ABD31835.1 ABD32002.1 ABD32002.1 ABD32003.1 ABD32003.1 ABD32004.1 ABD32004.1 ABD32005.1 ABD32005.1 ABD32006.1 ABD32006.1 ABD32007.1 ABD32007.1 ABD32008.1 ABD32008.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD29345.1Peptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (530 aa)
ABD29346.1Conserved hypothetical protein. (492 aa)
ABD29347.1Peptide ABC transporter, permease protein, putative. (387 aa)
ABD29348.1Conserved hypothetical protein. (591 aa)
ABD29350.1Conserved hypothetical protein. (257 aa)
azoRAcyl carrier phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (208 aa)
ABD29352.1M23/M37 peptidase domain protein. (192 aa)
ABD29353.1Multiple sugar-binding transport ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (365 aa)
ABD29354.1Bacterial extracellular solute-binding protein, putative. (423 aa)
ABD29355.1Maltose ABC transporter, permease protein, putative. (422 aa)
ABD29356.1Maltose ABC transporter, permease protein. (279 aa)
ABD29357.1Conserved hypothetical protein. (358 aa)
ABD29358.1Conserved hypothetical protein. (346 aa)
ABD29359.1Conserved hypothetical protein. (322 aa)
nikAConserved hypothetical protein; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Binds nickel and transfers it to the membrane-bound permease. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). May bind nickel via a nickel-chelator. (470 aa)
ABD29671.1Conserved hypothetical protein. (202 aa)
ABD29769.1Conserved hypothetical protein. (667 aa)
ABD29770.1ABC transporter, substrate-binding protein, putative; Belongs to the bacterial solute-binding protein 9 family. (312 aa)
ABD29771.1Iron (chelated) ABC transporter, permease protein, putative. (278 aa)
ABD29772.1Conserved hypothetical protein. (247 aa)
ABD29773.1Conserved hypothetical protein. (214 aa)
ABD30047.1Conserved hypothetical protein. (123 aa)
ABD30048.1Conserved hypothetical protein. (308 aa)
ABD30049.1Conserved hypothetical protein. (356 aa)
ABD30050.1Conserved hypothetical protein; Belongs to the ABC transporter superfamily. (360 aa)
ABD30051.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (313 aa)
ABD30052.1Oligopeptide ABC transporter, substrate-binding protein, putative. (551 aa)
ABD30053.1Oligopeptide ABC transporter, substrate-binding protein, putative. (571 aa)
ABD30054.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (328 aa)
ABD30055.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (326 aa)
ABD30056.1Oligopeptide ABC transporter, permease protein, putative. (320 aa)
ABD30057.1Oligopeptide ABC transporter, permease protein, putative. (293 aa)
ABD30141.1Conserved hypothetical protein. (268 aa)
ABD30142.1Conserved hypothetical protein. (466 aa)
ABD30143.1Conserved hypothetical protein. (191 aa)
ABD30144.1Hypothetical protein. (39 aa)
mntHConserved hypothetical protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family. (450 aa)
ABD30173.1Conserved hypothetical protein; Belongs to the UPF0637 family. (204 aa)
ABD30174.1Inositol monophosphatase family protein, putative. (275 aa)
ABD30175.1Hypothetical protein. (95 aa)
ABD30176.1GTP-binding protein TypA, putative. (615 aa)
ABD30471.1Conserved hypothetical protein. (157 aa)
nikEOligopeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for energy coupling to the transport system. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (233 aa)
nikDPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for energy coupling to the transport system. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (257 aa)
nikCOligopeptide transporter putative membrane permease domain; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for the translocation of the substrate across the membrane. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (276 aa)
nikBOligopeptide transporter putative membrane permease domain; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for the translocation of the substrate across the membrane. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (328 aa)
ABD30476.1Hypothetical protein. (61 aa)
ABD30477.1Conserved hypothetical protein. (114 aa)
ABD30478.1Conserved hypothetical protein. (604 aa)
xerDIntegrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (295 aa)
ABD30671.1Transcriptional regulator, Fur, putative; Belongs to the Fur family. (149 aa)
ABD30673.1Conserved hypothetical protein. (302 aa)
furConserved hypothetical protein; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. (136 aa)
ABD30731.1Conserved hypothetical protein. (287 aa)
ABD30732.1ABC transporter, putative. (261 aa)
nfoEndonuclease IV, putative; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. Belongs to the AP endonuclease 2 family. (296 aa)
cshBConserved hypothetical protein; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (448 aa)
ABD30735.1Conserved hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (366 aa)
ABD30736.1Conserved hypothetical protein. (225 aa)
sigARNA polymerase sigma factor, putative; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (368 aa)
dnaGDNA primase, putative; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (599 aa)
ABD30739.1Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (272 aa)
ABD30740.1CBS domain protein. (179 aa)
ABD31484.1Conserved hypothetical protein. (284 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (267 aa)
ecfTCobalt transport protein, putative; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (268 aa)
ecfA2ABC transporter, ATP-binding protein, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (286 aa)
ecfA1ABC transporter, ATP-binding protein, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (269 aa)
ABD31565.1Conserved hypothetical protein. (184 aa)
ABD31594.1Transcriptional regulator, putative. (307 aa)
ABD31595.1Conserved hypothetical protein. (265 aa)
ABD31698.1Conserved hypothetical protein; Belongs to the bacterial solute-binding protein 9 family. (516 aa)
ABD31766.1Conserved hypothetical protein. (397 aa)
cntFPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for energy coupling to the transport system. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro. (249 aa)
cntDPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for energy coupling to the transport system. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro. (271 aa)
cntCNickel ABC transporter, permease protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro ; Belongs to the binding-protein-dependent transport system permease family. (289 aa)
cntBPeptide ABC transporter, permease protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro ; Belongs to the binding-protein-dependent transport system permease family. (311 aa)
cntAPeptide ABC transporter, peptide-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Binds the metal via the metallophore StP, and transfers the StP-metal complex to the membrane-bound permease. Binds one molecule of StP/metal. Binds StP/Co(2+) and StP/Ni(2+) tighter than StP/Zn(2+). Plays a major role in nickel/cobalt import in zinc- depleted conditions. Contributes to virulence. Required for ful [...] (532 aa)
ABD31772.1Conserved hypothetical protein. (404 aa)
ABD31773.1Conserved hypothetical protein. (272 aa)
ABD31774.1Conserved hypothetical protein. (273 aa)
ABD31820.1Conserved hypothetical protein. (387 aa)
ABD31821.1Conserved hypothetical protein. (152 aa)
ABD31834.1Conserved hypothetical protein. (211 aa)
ABD31835.1Conserved hypothetical protein. (243 aa)
ABD32002.1Conserved hypothetical protein. (374 aa)
ABD32003.1Conserved hypothetical protein. (165 aa)
ABD32004.1Conserved hypothetical protein. (277 aa)
ABD32005.1ABC transporter, ATP-binding protein, putative. (570 aa)
ABD32006.1Conserved hypothetical protein. (184 aa)
ABD32007.1Conserved hypothetical protein. (282 aa)
ABD32008.1Conserved hypothetical protein; Belongs to the UPF0312 family. (171 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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