STRINGSTRING
ABD29345.1 ABD29345.1 ABD29346.1 ABD29346.1 ABD29347.1 ABD29347.1 ABD29348.1 ABD29348.1 nikA nikA ABD30048.1 ABD30048.1 ABD30049.1 ABD30049.1 ABD30050.1 ABD30050.1 ABD30051.1 ABD30051.1 ABD30052.1 ABD30052.1 ABD30053.1 ABD30053.1 ABD30054.1 ABD30054.1 ABD30055.1 ABD30055.1 ABD30056.1 ABD30056.1 ABD30057.1 ABD30057.1 nikE nikE nikD nikD nikC nikC nikB nikB ABD31766.1 ABD31766.1 cntF cntF cntD cntD cntC cntC cntB cntB cntA cntA ABD31772.1 ABD31772.1 ABD31773.1 ABD31773.1 ABD31774.1 ABD31774.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD29345.1Peptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (530 aa)
ABD29346.1Conserved hypothetical protein. (492 aa)
ABD29347.1Peptide ABC transporter, permease protein, putative. (387 aa)
ABD29348.1Conserved hypothetical protein. (591 aa)
nikAConserved hypothetical protein; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Binds nickel and transfers it to the membrane-bound permease. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). May bind nickel via a nickel-chelator. (470 aa)
ABD30048.1Conserved hypothetical protein. (308 aa)
ABD30049.1Conserved hypothetical protein. (356 aa)
ABD30050.1Conserved hypothetical protein; Belongs to the ABC transporter superfamily. (360 aa)
ABD30051.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (313 aa)
ABD30052.1Oligopeptide ABC transporter, substrate-binding protein, putative. (551 aa)
ABD30053.1Oligopeptide ABC transporter, substrate-binding protein, putative. (571 aa)
ABD30054.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (328 aa)
ABD30055.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (326 aa)
ABD30056.1Oligopeptide ABC transporter, permease protein, putative. (320 aa)
ABD30057.1Oligopeptide ABC transporter, permease protein, putative. (293 aa)
nikEOligopeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for energy coupling to the transport system. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (233 aa)
nikDPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for energy coupling to the transport system. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (257 aa)
nikCOligopeptide transporter putative membrane permease domain; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for the translocation of the substrate across the membrane. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (276 aa)
nikBOligopeptide transporter putative membrane permease domain; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for the translocation of the substrate across the membrane. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). (328 aa)
ABD31766.1Conserved hypothetical protein. (397 aa)
cntFPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for energy coupling to the transport system. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro. (249 aa)
cntDPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for energy coupling to the transport system. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro. (271 aa)
cntCNickel ABC transporter, permease protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro ; Belongs to the binding-protein-dependent transport system permease family. (289 aa)
cntBPeptide ABC transporter, permease protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro ; Belongs to the binding-protein-dependent transport system permease family. (311 aa)
cntAPeptide ABC transporter, peptide-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Binds the metal via the metallophore StP, and transfers the StP-metal complex to the membrane-bound permease. Binds one molecule of StP/metal. Binds StP/Co(2+) and StP/Ni(2+) tighter than StP/Zn(2+). Plays a major role in nickel/cobalt import in zinc- depleted conditions. Contributes to virulence. Required for ful [...] (532 aa)
ABD31772.1Conserved hypothetical protein. (404 aa)
ABD31773.1Conserved hypothetical protein. (272 aa)
ABD31774.1Conserved hypothetical protein. (273 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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