STRINGSTRING
ABD29635.1 ABD29635.1 ABD29781.1 ABD29781.1 murB murB murE murE ABD30180.1 ABD30180.1 murI murI mraZ mraZ rsmH rsmH ftsL ftsL ABD30255.1 ABD30255.1 mraY mraY murD murD divIB divIB ftsA ftsA ftsZ ftsZ ABD30261.1 ABD30261.1 ABD30262.1 ABD30262.1 sepF sepF ABD30264.1 ABD30264.1 ABD30265.1 ABD30265.1 ABD30266.1 ABD30266.1 murG murG ABD30552.1 ABD30552.1 ABD30728.1 ABD30728.1 ABD30908.1 ABD30908.1 murC murC mgt mgt alr1 alr1 murF murF ddl ddl ABD31353.1 ABD31353.1 murA murA murA-2 murA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD29635.1Conserved hypothetical protein. (130 aa)
ABD29781.1Penicillin-binding protein 4, putative; Belongs to the peptidase S11 family. (431 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase, putative; Cell wall formation. (307 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Cannot use diaminopimelate as substrate. Seems to have a role in beta-lactam antibiotic resistance. (493 aa)
ABD30180.1Conserved hypothetical protein; Belongs to the SEDS family. (408 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (266 aa)
mraZConserved hypothetical protein; Belongs to the MraZ family. (143 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (304 aa)
ftsLConserved hypothetical protein; Essential cell division protein; Belongs to the FtsL family. (133 aa)
ABD30255.1Penicillin-binding protein 1. (744 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (321 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (449 aa)
divIBCell division protein, putative; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (439 aa)
ftsACell division protein, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. (470 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (390 aa)
ABD30261.1Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (221 aa)
ABD30262.1Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (222 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (187 aa)
ABD30264.1Conserved hypothetical protein. (96 aa)
ABD30265.1Conserved hypothetical protein. (268 aa)
ABD30266.1Conserved hypothetical protein. (205 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (356 aa)
ABD30552.1Penicillin-binding protein 2. (727 aa)
ABD30728.1Penicillin-binding protein 3. (691 aa)
ABD30908.1Transglycosylase domain protein. (301 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (437 aa)
mgtTransglycosylase domain protein; Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate. (269 aa)
alr1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (382 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (356 aa)
ABD31353.1Conserved hypothetical protein; Belongs to the SEDS family. (400 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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