STRINGSTRING
ABD29820.1 ABD29820.1 ABD32019.1 ABD32019.1 ABD32003.1 ABD32003.1 icaC icaC ABD31984.1 ABD31984.1 ABD31924.1 ABD31924.1 ABD31882.1 ABD31882.1 oatA oatA ABD31869.1 ABD31869.1 ABD31837.1 ABD31837.1 ABD31829.1 ABD31829.1 ABD31721.1 ABD31721.1 ABD31694.1 ABD31694.1 ABD31661.1 ABD31661.1 ABD31659.1 ABD31659.1 ABD31564.1 ABD31564.1 ABD31535.1 ABD31535.1 ABD31401.1 ABD31401.1 fabZ fabZ ABD31316.1 ABD31316.1 tsaD tsaD ABD31288.1 ABD31288.1 ABD30914.1 ABD30914.1 ABD30905.1 ABD30905.1 lipM lipM ABD30690.1 ABD30690.1 ABD30518.1 ABD30518.1 odhB odhB dapH dapH plsY plsY ABD30305.1 ABD30305.1 ABD30304.1 ABD30304.1 plsX plsX ABD30248.1 ABD30248.1 ABD30162.1 ABD30162.1 ABD30119.1 ABD30119.1 ABD30115.1 ABD30115.1 ABD30104.1 ABD30104.1 ABD30088.1 ABD30088.1 fabI fabI ABD30046.1 ABD30046.1 fabH fabH ABD30036.1 ABD30036.1 ABD29956.1 ABD29956.1 ABD29939.1 ABD29939.1 ABD29817.1 ABD29817.1 ABD29796.1 ABD29796.1 ABD29743.1 ABD29743.1 lipL lipL ABD29717.1 ABD29717.1 ABD29705.1 ABD29705.1 ABD29680.1 ABD29680.1 ABD29659.1 ABD29659.1 glmU glmU ABD29600.1 ABD29600.1 ABD29590.1 ABD29590.1 ABD29504.1 ABD29504.1 ABD29492.1 ABD29492.1 ABD29477.1 ABD29477.1 ABD29373.1 ABD29373.1 pflB pflB argJ argJ ABD29203.1 ABD29203.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD29820.1Conserved hypothetical protein. (180 aa)
ABD32019.1Conserved hypothetical protein; Belongs to the arylamine N-acetyltransferase family. (264 aa)
ABD32003.1Conserved hypothetical protein. (165 aa)
icaCIntercellular adhesion protein C, putative; Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane. (350 aa)
ABD31984.1Conserved hypothetical protein. (166 aa)
ABD31924.1acetyl-CoA synthetase, putative. (532 aa)
ABD31882.1Conserved hypothetical protein. (162 aa)
oatAConserved hypothetical protein; Responsible for O-acetylation at the C(6)-hydroxyl group of N-acetylmuramyl residues, forming the corresponding N,6-O- diacetylmuramic acid of the peptidoglycan. O-acetylation of the peptidoglycan is the major determinant for lysozyme resistance. Belongs to the acyltransferase 3 family. (603 aa)
ABD31869.1Conserved hypothetical protein. (199 aa)
ABD31837.1Conserved hypothetical protein. (163 aa)
ABD31829.1Conserved hypothetical protein. (94 aa)
ABD31721.1Conserved hypothetical protein. (371 aa)
ABD31694.1Conserved hypothetical protein. (178 aa)
ABD31661.1Conserved hypothetical protein. (111 aa)
ABD31659.1Conserved hypothetical protein. (171 aa)
ABD31564.1Conserved hypothetical protein. (256 aa)
ABD31535.1Conserved hypothetical protein. (295 aa)
ABD31401.1Conserved hypothetical protein. (286 aa)
fabZbeta-hydroxyacyl-ACP dehydratase, putative; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
ABD31316.1Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (136 aa)
tsaDO-sialoglycoprotein endopeptidase, putative; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (By similarity). Critical mediator involved in the modification of cell wall peptidoglycan synthesis and/or cell division as well as in the positive regulation of the activities of different murein [...] (341 aa)
ABD31288.1Conserved hypothetical protein. (147 aa)
ABD30914.1Conserved hypothetical protein. (210 aa)
ABD30905.11-acyl-sn-glycerol-3-phosphate acyltransferases domain protein. (205 aa)
lipMConserved hypothetical protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (276 aa)
ABD30690.12-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase, putative. (424 aa)
ABD30518.1Conserved hypothetical protein. (169 aa)
odhB2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (422 aa)
dapH2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase, putative; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (239 aa)
plsYConserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (202 aa)
ABD30305.13-oxoacyl-(acyl-carrier-protein) reductase, putative; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
ABD30304.1Malonyl CoA-acyl carrier protein transacylase. (308 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (328 aa)
ABD30248.1Conserved hypothetical protein. (146 aa)
ABD30162.1Dihydrolipoamide S-acetyltransferase component of pyruvate dehydrogenase complex E2, putative. (430 aa)
ABD30119.1Conserved hypothetical protein; Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product. (144 aa)
ABD30115.1Conserved hypothetical protein. (336 aa)
ABD30104.1Conserved hypothetical protein. (183 aa)
ABD30088.1Lipoyltransferase and lipoate-protein ligase, putative. (328 aa)
fabIEnoyl-(acyl-carrier-protein) reductase; Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It has a preference for a long chain (C12) substrate compared to the shorter (C4) acyl group. Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity). (256 aa)
ABD30046.13-oxoacyl- synthase, putative; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
fabHConserved hypothetical protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (313 aa)
ABD30036.1Conserved hypothetical protein. (604 aa)
ABD29956.1Conserved hypothetical protein. (164 aa)
ABD29939.1Conserved hypothetical protein. (176 aa)
ABD29817.1Conserved hypothetical protein. (147 aa)
ABD29796.1Conserved hypothetical protein. (168 aa)
ABD29743.1Conserved hypothetical protein. (158 aa)
lipLConserved hypothetical protein; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (254 aa)
ABD29717.1Phosphate acetyltransferase. (328 aa)
ABD29705.1acetyl-CoA acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (379 aa)
ABD29680.1Conserved hypothetical protein. (395 aa)
ABD29659.1Serine acetyltransferase, putative. (215 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (450 aa)
ABD29600.1Conserved hypothetical protein. (174 aa)
ABD29590.1Conserved hypothetical protein. (161 aa)
ABD29504.1acetyl-CoA acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ABD29492.1Ribosomal-protein-serine acetyltransferase, putative. (181 aa)
ABD29477.1Conserved hypothetical protein. (340 aa)
ABD29373.1acetyl-CoA acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
pflBFormate acetyltransferase; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. (749 aa)
argJGlutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa)
ABD29203.1Conserved hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family. (322 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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