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| | purB | Adenylosuccinate lyase. (431 aa) |
| | ABD31183.1 | Conserved hypothetical protein. (264 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (562 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (456 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (190 aa) |
| | ilvA | Thereonine dehydratase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). (422 aa) |
| | fabZ | beta-hydroxyacyl-ACP dehydratase, putative; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | ABD31397.1 | Conserved hypothetical protein. (286 aa) |
| | luxS | Autoinducer-2 production protein LuxS, putative; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (156 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (374 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (139 aa) |
| | menB | enoyl-CoA hydratase/isomerase family protein, putative; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (273 aa) |
| | menH | Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (267 aa) |
| | argH | Argininosuccinate lyase. (459 aa) |
| | aroD | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (238 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP). (164 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (553 aa) |
| | ABD31693.1 | Conserved hypothetical protein. (243 aa) |
| | ABD31840.1 | L-serine dehydratase, iron-sulfur-dependent, alpha subunit. (299 aa) |
| | ABD31841.1 | L-serine dehydratase, iron-sulfur-dependent, beta subunit. (226 aa) |
| | ABD31895.1 | Conserved hypothetical protein. (336 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (123 aa) |
| | ABD31916.1 | Alpha-acetolactate decarboxylase. (234 aa) |
| | fda | Fructose-bisphosphate aldolase class-I, putative. (296 aa) |
| | ABD31939.1 | Siroheme synthase, putative. (201 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. (462 aa) |
| | hisH | Imidazole glycerol phosphate synthase, subunit H (hisH), putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (192 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase, putative. (192 aa) |
| | ABD29855.1 | Para-aminobenzoate synthase, glutamine amidotransferase, component II, putative. (197 aa) |
| | ABD29853.1 | 6-pyruvoyl tetrahydropterin synthase superfamily, putative. (139 aa) |
| | queE | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (237 aa) |
| | ABD29838.1 | Conserved hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (160 aa) |
| | ABD29832.1 | Deoxyribodipyrimidine photolyase, putative; Belongs to the DNA photolyase family. (457 aa) |
| | ABD29720.1 | Diphosphomevalonate decarboxylase. (327 aa) |
| | ABD29700.1 | Conserved hypothetical protein; Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. (210 aa) |
| | hchA | Conserved hypothetical protein; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbino [...] (292 aa) |
| | pdxT | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (186 aa) |
| | pdxS | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (295 aa) |
| | ABD29643.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (121 aa) |
| | ABD29641.1 | Conserved hypothetical protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa) |
| | ABD29583.1 | Trans-sulfuration enzyme family protein, putative. (380 aa) |
| | ABD29582.1 | Conserved hypothetical protein. (304 aa) |
| | ABD29509.1 | Conserved hypothetical protein. (367 aa) |
| | ABD29508.1 | Trans-sulfuration enzyme family protein. (386 aa) |
| | nanA | N-acetylneuraminate lyase subunit, putative; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (293 aa) |
| | psuG | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (307 aa) |
| | ABD29374.1 | Conserved hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family. (753 aa) |
| | murQ | Conserved hypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (298 aa) |
| | ABD29333.1 | Indolepyruvate decarboxylase, putative. (546 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | sbnH | Conserved hypothetical protein; Catalyzes the decarboxylation of citryl-L-2,3- diaminopropionic acid to citryl-diaminoethane, the second step in staphyloferrin B biosynthesis; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (400 aa) |
| | ABD29264.1 | Conserved hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (258 aa) |
| | sbnA | Conserved hypothetical protein; Catalyzes the synthesis of N-((2S)-2-amino-2-carboxyethyl)-L- glutamate (ACEGA) from O-phospho-L-serine and L-glutamate. Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics. (281 aa) |
| | ABD29248.1 | Conserved hypothetical protein. (591 aa) |
| | plc | 1-phosphatidylinositol phosphodiesterase precursor, putative; Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor (By similarity). (328 aa) |
| | hutH | Histidine ammonia-lyase; Belongs to the PAL/histidase family. (504 aa) |
| | nnrD | Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (233 aa) |
| | deoC-2 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | moaA | Molybdopterin cofactor biosynthesis protein A, putative; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (340 aa) |
| | dacA | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (269 aa) |
| | lacD | Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (326 aa) |
| | hysA | Hyaluronate lyase; Belongs to the polysaccharide lyase 8 family. (807 aa) |
| | ABD31487.1 | Alpha-acetolactate decarboxylase. (234 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (230 aa) |
| | ABD30285.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa) |
| | ABD30406.1 | Conserved hypothetical protein. (341 aa) |
| | ABD30419.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa) |
| | ABD30443.1 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (901 aa) |
| | ABD30461.1 | Anthranilate synthase component I. (468 aa) |
| | trpC | Indole-3-glycerol phosphate synthase, putative; Belongs to the TrpC family. (260 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (242 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | tdcB | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). Belongs to the serine/thre [...] (346 aa) |
| | nth | Endonuclease III, putative; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (219 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (354 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa) |
| | ABD30666.1 | Ribosomal large subunit pseudouridine synthase B, putative; Belongs to the pseudouridine synthase RsuA family. (245 aa) |
| | ABD30807.1 | Conserved hypothetical protein. (257 aa) |
| | hemB | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). (324 aa) |
| | ABD30842.1 | uroporphyrinogen-III synthase, putative; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (222 aa) |
| | ABD30864.1 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (290 aa) |
| | ABD30878.1 | NADP-dependent malic enzyme, putative. (409 aa) |
| | ABD30918.1 | Conserved hypothetical protein. (363 aa) |
| | ABD30935.1 | Ribosomal small subunit pseudouridine synthase A, putative; Belongs to the pseudouridine synthase RsuA family. (231 aa) |
| | ribBA | Riboflavin biosynthesis protein, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (393 aa) |
| | ABD30964.1 | Conserved hypothetical protein. (237 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa) |
| | menC | Conserved hypothetical protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (333 aa) |
| | ABD31011.1 | Flavoprotein, epiD, putative. (172 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (307 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (345 aa) |
| | ABD31041.1 | Ribosomal large subunit pseudouridine synthase, RluD subfamily, putative. (273 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa) |
