STRINGSTRING
gcvPB gcvPB ABD31998.1 ABD31998.1 ABD31919.1 ABD31919.1 ABD31874.1 ABD31874.1 bioA bioA ABD31721.1 ABD31721.1 glyA glyA ABD31206.1 ABD31206.1 hemL2 hemL2 ABD30900.1 ABD30900.1 ABD30893.1 ABD30893.1 hemL1 hemL1 ABD30800.1 ABD30800.1 gcvPA gcvPA ABD30406.1 ABD30406.1 ABD30384.1 ABD30384.1 ABD30114.1 ABD30114.1 rocD-2 rocD-2 ABD29975.1 ABD29975.1 hisC hisC ABD29680.1 ABD29680.1 ABD29647.1 ABD29647.1 ABD29605.1 ABD29605.1 ABD29583.1 ABD29583.1 ABD29509.1 ABD29509.1 ABD29508.1 ABD29508.1 rocD rocD norG norG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvPBGlycine cleavage system P-protein subunit ll, putative; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (490 aa)
ABD31998.1Histidinol-phosphate aminotransferase, putative. (337 aa)
ABD31919.1Conserved hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
ABD31874.1Conserved hypothetical protein. (384 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (452 aa)
ABD31721.1Conserved hypothetical protein. (371 aa)
glyASerine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
ABD31206.1Conserved hypothetical protein. (428 aa)
hemL2Glutamate-1-semialdehyde-2,1-aminomutase, putative. (391 aa)
ABD30900.1Conserved hypothetical protein. (386 aa)
ABD30893.1Conserved hypothetical protein. (382 aa)
hemL1Glutamate-1-semialdehyde-2,1-aminomutase. (428 aa)
ABD30800.1Conserved hypothetical protein. (380 aa)
gcvPAGlycine cleavage system P-protein subunit I, putative; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
ABD30406.1Conserved hypothetical protein. (341 aa)
ABD30384.1Conserved hypothetical protein. (412 aa)
ABD30114.1Conserved hypothetical protein. (384 aa)
rocD-2Ornithine aminotransferase, putative; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (396 aa)
ABD29975.1Aminotransferase, class V superfamily, putative; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (352 aa)
ABD29680.1Conserved hypothetical protein. (395 aa)
ABD29647.1Conserved hypothetical protein. (460 aa)
ABD29605.1Orn/Lys/Arg decarboxylase, putative. (445 aa)
ABD29583.1Trans-sulfuration enzyme family protein, putative. (380 aa)
ABD29509.1Conserved hypothetical protein. (367 aa)
ABD29508.1Trans-sulfuration enzyme family protein. (386 aa)
rocDOrnithine aminotransferase, putative; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (394 aa)
norGConserved hypothetical protein; Positively regulates the expression of the NorB efflux pump and negatively regulates the expression of the AbcA efflux pump. Binds specifically to the promoters of norA, norB and norC and abcA genes. Overexpression of norG leads to an increase in the level of resistance to quinolones, associated with a threefold increase in norB transcripts. Disruption of norG leads to an increase in the level of resistance to methicillin, cefotaxime, penicillin G, and nafcillin, associated with a threefold increase in abcA transcripts. Could also have an aminotransferas [...] (465 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.