STRINGSTRING
ABD31236.1 ABD31236.1 aldH1 aldH1 pckA pckA ABD30913.1 ABD30913.1 pfkA pfkA pyk pyk ABD30862.1 ABD30862.1 ABD30722.1 ABD30722.1 ABD30693.1 ABD30693.1 ABD30522.1 ABD30522.1 ABD30368.1 ABD30368.1 ABD30367.1 ABD30367.1 ABD30163.1 ABD30163.1 ABD30162.1 ABD30162.1 ABD30161.1 ABD30161.1 pdhA pdhA pgi pgi ABD29294.1 ABD29294.1 aldA aldA ABD29339.1 ABD29339.1 ldh1 ldh1 ABD29386.1 ABD29386.1 ABD29411.1 ABD29411.1 ABD29466.1 ABD29466.1 ABD29526.1 ABD29526.1 ABD29636.1 ABD29636.1 ABD29723.1 ABD29723.1 ABD29923.1 ABD29923.1 adh adh pgk pgk tpiA tpiA gpmI gpmI eno eno ABD30017.1 ABD30017.1 ABD31924.1 ABD31924.1 fda fda ldh2 ldh2 fbp fbp pgcA pgcA ABD31773.1 ABD31773.1 gpmA gpmA ABD31624.1 ABD31624.1 ABD31609.1 ABD31609.1 ABD31600.1 ABD31600.1 lacG lacG ABD31397.1 ABD31397.1 ABD31394.1 ABD31394.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD31236.1Prohead protease. (194 aa)
aldH1Aldehyde dehydrogenase, putative; Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes the oxidation of 4,4'- diaponeurosporen-4-al to yield 4,4'-diaponeurosporenoic acid. Belongs to the aldehyde dehydrogenase family. (459 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
ABD30913.1acetyl-CoA synthetase, putative. (568 aa)
pfkA6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (307 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
ABD30862.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
ABD30722.1Glucokinase, putative. (328 aa)
ABD30693.1Dihydrolipoamide dehydrogenase. (473 aa)
ABD30522.1Phosphotransferase system enzyme IIA, putative. (166 aa)
ABD30368.1Conserved hypothetical protein. (288 aa)
ABD30367.1Conserved hypothetical protein. (586 aa)
ABD30163.1Dihydrolipoamide dehydrogenase. (468 aa)
ABD30162.1Dihydrolipoamide S-acetyltransferase component of pyruvate dehydrogenase complex E2, putative. (430 aa)
ABD30161.1Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase beta subunit, putative. (325 aa)
pdhAPyruvate dehydrogenase complex, E1 component, alpha subunit, putative; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (370 aa)
pgiGlucose-6-phosphate isomerase. (443 aa)
ABD29294.1Alcohol dehydrogenase, iron-containing, putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (869 aa)
aldAAldehyde dehydrogenase, putative. (495 aa)
ABD29339.1Conserved hypothetical protein. (291 aa)
ldh1L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate (Potential). Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity). (269 aa)
ABD29386.1PTS system, glucose-specific IIBC component, putative. (509 aa)
ABD29411.16-phospho-beta-glucosidase, putative; Belongs to the glycosyl hydrolase 1 family. (478 aa)
ABD29466.1Conserved hypothetical protein. (266 aa)
ABD29526.1Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family. (193 aa)
ABD29636.1S1 RNA binding domain protein. (133 aa)
ABD29723.1Conserved hypothetical protein. (440 aa)
ABD29923.1Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
adhAlcohol dehydrogenase I, putative. (336 aa)
pgkPhosphoglycerate kinase, putative; Belongs to the phosphoglycerate kinase family. (396 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (505 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
ABD30017.1Conserved hypothetical protein. (114 aa)
ABD31924.1acetyl-CoA synthetase, putative. (532 aa)
fdaFructose-bisphosphate aldolase class-I, putative. (296 aa)
ldh2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate (Potential). Contributes to S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells, despite playing a secondary role in this resistance mechanism (By similarity). (319 aa)
fbpConserved hypothetical protein. (654 aa)
pgcAConserved hypothetical protein; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate (Probable). This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Belongs to the phosphohexose mutase family. (602 aa)
ABD31773.1Conserved hypothetical protein. (272 aa)
gpmAPhosphoglycerate mutase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (228 aa)
ABD31624.1Aldose 1-epimerase precursor, putative. (339 aa)
ABD31609.1Hex regulon repressor, putative. (254 aa)
ABD31600.1Conserved hypothetical protein. (290 aa)
lacG6-phospho-beta-galactosidase; Belongs to the glycosyl hydrolase 1 family. (470 aa)
ABD31397.1Conserved hypothetical protein. (286 aa)
ABD31394.1Aldehyde dehydrogenase, putative. (475 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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