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carB carB purA purA ABD29594.1 ABD29594.1 ABD29595.1 ABD29595.1 ABD30020.1 ABD30020.1 argH argH argG argG purQ purQ purF purF pyrB pyrB carA carA ABD30386.1 ABD30386.1 ald1 ald1 ABD30582.1 ABD30582.1 ABD30636.1 ABD30636.1 ald2 ald2 purB purB ABD31206.1 ABD31206.1 ABD31251.1 ABD31251.1 ABD31298.1 ABD31298.1 glmS glmS rocA rocA ABD31919.1 ABD31919.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
carBCarbamoyl-phosphate synthase, large subunit. (1057 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa)
ABD29594.1Glutamate synthase, large subunit, putative. (1499 aa)
ABD29595.1NADH-glutamate synthase small subunit, putative. (487 aa)
ABD30020.1Glutamate dehydrogenase, NAD-specific, putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (414 aa)
argHArgininosuccinate lyase. (459 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (494 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (293 aa)
carACarbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (366 aa)
ABD30386.1Glutamine synthetase, type I. (446 aa)
ald1Alanine dehydrogenase; May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer. (372 aa)
ABD30582.1L-asparaginase, putative. (322 aa)
ABD30636.1Conserved hypothetical phage protein. (115 aa)
ald2Alanine dehydrogenase; May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer. (372 aa)
purBAdenylosuccinate lyase. (431 aa)
ABD31206.1Conserved hypothetical protein. (428 aa)
ABD31251.1Conserved hypothetical phage protein. (115 aa)
ABD31298.1Conserved hypothetical protein. (261 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (601 aa)
rocADelta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. RocA subfamily. (514 aa)
ABD31919.1Conserved hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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