STRINGSTRING
ABD30430.1 ABD30430.1 ABD30443.1 ABD30443.1 ABD30693.1 ABD30693.1 gcvPB gcvPB gcvPA gcvPA gcvT gcvT ABD30870.1 ABD30870.1 ABD29991.1 ABD29991.1 gcvH gcvH ABD29702.1 ABD29702.1 ABD29322.1 ABD29322.1 ABD29474.1 ABD29474.1 ABD29505.1 ABD29505.1 ABD29686.1 ABD29686.1 ABD31924.1 ABD31924.1 ABD31731.1 ABD31731.1 ABD29961.1 ABD29961.1 ABD31593.1 ABD31593.1 ABD31589.1 ABD31589.1 glyA glyA ABD31054.1 ABD31054.1 ABD30913.1 ABD30913.1 ABD30903.1 ABD30903.1 ABD29888.1 ABD29888.1 ABD29723.1 ABD29723.1 ABD29705.1 ABD29705.1 spxA spxA ABD30163.1 ABD30163.1 ABD30186.1 ABD30186.1 ABD30386.1 ABD30386.1 katA katA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD30430.1Conserved hypothetical protein. (287 aa)
ABD30443.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (901 aa)
ABD30693.1Dihydrolipoamide dehydrogenase. (473 aa)
gcvPBGlycine cleavage system P-protein subunit ll, putative; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (490 aa)
gcvPAGlycine cleavage system P-protein subunit I, putative; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (363 aa)
ABD30870.1Conserved hypothetical protein; Belongs to the citrate synthase family. (285 aa)
ABD29991.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. (294 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (126 aa)
ABD29702.1Hydrolase, haloacid dehalogenase-like. (215 aa)
ABD29322.1Formate dehydrogenase, NAD-dependent, putative; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (341 aa)
ABD29474.1Conserved hypothetical protein. (90 aa)
ABD29505.1Conserved hypothetical protein. (250 aa)
ABD29686.1Haloacid dehalogenase-like hydrolase, putative. (227 aa)
ABD31924.1acetyl-CoA synthetase, putative. (532 aa)
ABD31731.1Glycerate kinase, putative; Belongs to the glycerate kinase type-1 family. (380 aa)
ABD29961.1Conserved hypothetical protein; Belongs to the ArsC family. (118 aa)
ABD31593.1Formate dehydrogenase, alpha subunit, putative; In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (984 aa)
ABD31589.1D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. (317 aa)
glyASerine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
ABD31054.1Conserved hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
ABD30913.1acetyl-CoA synthetase, putative. (568 aa)
ABD30903.1Conserved hypothetical protein. (376 aa)
ABD29888.1Conserved hypothetical protein. (374 aa)
ABD29723.1Conserved hypothetical protein. (440 aa)
ABD29705.1acetyl-CoA acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (379 aa)
spxAConserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (131 aa)
ABD30163.1Dihydrolipoamide dehydrogenase. (468 aa)
ABD30186.1Conserved hypothetical protein. (273 aa)
ABD30386.1Glutamine synthetase, type I. (446 aa)
katACatalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in resistance to paraquat when fur is absent and to tert-butyl hydroperoxide. Is important for survival under glucose starvation and desiccation conditions. Not required for virulence although is necessary for nasal colonization. (473 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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