STRINGSTRING
ABD29286.1 ABD29286.1 ABD29312.1 ABD29312.1 ABD29317.1 ABD29317.1 ABD29318.1 ABD29318.1 ABD29319.1 ABD29319.1 ABD29341.1 ABD29341.1 ABD29345.1 ABD29345.1 ABD29353.1 ABD29353.1 ABD29354.1 ABD29354.1 ABD29355.1 ABD29355.1 ABD29356.1 ABD29356.1 ABD29364.1 ABD29364.1 rbsD rbsD ABD29424.1 ABD29424.1 ABD29425.1 ABD29425.1 ABD29426.1 ABD29426.1 esaA esaA ABD29456.1 ABD29456.1 ABD29457.1 ABD29457.1 ABD29501.1 ABD29501.1 ABD29511.1 ABD29511.1 ABD29537.1 ABD29537.1 metN1 metN1 ABD29585.1 ABD29585.1 ABD29586.1 ABD29586.1 tuf tuf ABD29751.1 ABD29751.1 ABD29752.1 ABD29752.1 ABD29770.1 ABD29770.1 ABD29771.1 ABD29771.1 ABD29772.1 ABD29772.1 ABD29773.1 ABD29773.1 tagH tagH ABD29777.1 ABD29777.1 ABD29782.1 ABD29782.1 ABD29786.1 ABD29786.1 ABD29787.1 ABD29787.1 ABD29788.1 ABD29788.1 ABD29800.1 ABD29800.1 ABD29801.1 ABD29801.1 ABD29825.1 ABD29825.1 ABD29826.1 ABD29826.1 ABD29862.1 ABD29862.1 ABD29864.1 ABD29864.1 ABD29865.1 ABD29865.1 metN2 metN2 ABD29969.1 ABD29969.1 ABD29970.1 ABD29970.1 ABD30048.1 ABD30048.1 ABD30049.1 ABD30049.1 ABD30050.1 ABD30050.1 ABD30051.1 ABD30051.1 ABD30052.1 ABD30052.1 ABD30095.1 ABD30095.1 ABD30101.1 ABD30101.1 fmtA fmtA ABD30141.1 ABD30141.1 ABD30142.1 ABD30142.1 potA potA ABD30167.1 ABD30167.1 ABD30168.1 ABD30168.1 ABD30169.1 ABD30169.1 isdE isdE isdF isdF ABD30202.1 ABD30202.1 ABD30385.1 ABD30385.1 ABD30409.1 ABD30409.1 ABD30410.1 ABD30410.1 sbcC sbcC ABD30440.1 ABD30440.1 pstB pstB ABD30481.1 ABD30481.1 ABD30482.1 ABD30482.1 pstS pstS ABD30487.1 ABD30487.1 ABD30731.1 ABD30731.1 ABD30732.1 ABD30732.1 ABD30844.1 ABD30844.1 ABD30963.1 ABD30963.1 ABD31007.1 ABD31007.1 ABD31008.1 ABD31008.1 ABD31009.1 ABD31009.1 ABD31027.1 ABD31027.1 ABD31049.1 ABD31049.1 ABD31050.1 ABD31050.1 ABD31059.1 ABD31059.1 ABD31064.1 ABD31064.1 ABD31065.1 ABD31065.1 ABD31199.1 ABD31199.1 ABD31200.1 ABD31200.1 ABD31202.1 ABD31202.1 ABD31286.1 ABD31286.1 ABD31295.1 ABD31295.1 ABD31312.1 ABD31312.1 ABD31427.1 ABD31427.1 ABD31451.1 ABD31451.1 ABD31452.1 ABD31452.1 ABD31453.1 ABD31453.1 ecfT ecfT ecfA2 ecfA2 ecfA1 ecfA1 ABD31560.1 ABD31560.1 ABD31561.1 ABD31561.1 ABD31562.1 ABD31562.1 ABD31565.1 ABD31565.1 ABD31567.1 ABD31567.1 ABD31598.1 ABD31598.1 lyrA lyrA ABD31627.1 ABD31627.1 ABD31628.1 ABD31628.1 hrtA hrtA hrtB hrtB ABD31666.1 ABD31666.1 ABD31698.1 ABD31698.1 ABD31705.1 ABD31705.1 ABD31706.1 ABD31706.1 ABD31707.1 ABD31707.1 ABD31726.1 ABD31726.1 ABD31727.1 ABD31727.1 flp flp ABD31747.1 ABD31747.1 ABD31748.1 ABD31748.1 ABD31749.1 ABD31749.1 ABD31750.1 ABD31750.1 ABD31758.1 ABD31758.1 ABD31765.1 ABD31765.1 cntF cntF cntD cntD cntC cntC cntB cntB cntA cntA ABD31822.1 ABD31822.1 ABD31823.1 ABD31823.1 ABD31834.1 ABD31834.1 ABD31835.1 ABD31835.1 ABD31944.1 ABD31944.1 ABD31945.1 ABD31945.1 isaB isaB ABD31966.1 ABD31966.1 ABD32004.1 ABD32004.1 ABD32005.1 ABD32005.1 ABD32021.1 ABD32021.1 ABD32022.1 ABD32022.1 ABD29255.1 ABD29255.1 ABD29256.1 ABD29256.1 ABD29257.1 ABD29257.1 ABD29283.1 ABD29283.1 ABD29284.1 ABD29284.1 phnC phnC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD29286.1Phosphonate ABC transporter, substrate-binding protein, putative. (318 aa)
ABD29312.1Conserved hypothetical protein. (127 aa)
ABD29317.1Conserved hypothetical protein. (246 aa)
ABD29318.1Conserved hypothetical protein. (324 aa)
ABD29319.1Conserved hypothetical protein. (253 aa)
ABD29341.1Type I site-specific deoxyribonuclease, HsdR family, putative; Subunit R is required for both nuclease and ATPase activities, but not for modification. (929 aa)
ABD29345.1Peptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (530 aa)
ABD29353.1Multiple sugar-binding transport ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (365 aa)
ABD29354.1Bacterial extracellular solute-binding protein, putative. (423 aa)
ABD29355.1Maltose ABC transporter, permease protein, putative. (422 aa)
ABD29356.1Maltose ABC transporter, permease protein. (279 aa)
ABD29364.1Lipoprotein, putative. (322 aa)
rbsDRibose ABC transporter protein, putative; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (134 aa)
ABD29424.1Conserved hypothetical protein. (219 aa)
ABD29425.1Conserved hypothetical protein. (306 aa)
ABD29426.1Conserved hypothetical protein. (388 aa)
esaAConserved hypothetical protein; Component of the type VII secretion system (Ess). Provides together with EssB and other components such as EssC and EssE a secretion platform across the cytoplasmic membrane in the host. (1009 aa)
ABD29456.1Conserved hypothetical protein. (349 aa)
ABD29457.1ABC transporter, ATP-binding protein, putative. (225 aa)
ABD29501.1ABC transporter, ATP-binding protein, putative. (280 aa)
ABD29511.1Conserved hypothetical protein. (293 aa)
ABD29537.1Conserved hypothetical protein. (135 aa)
metN1Conserved hypothetical protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)
ABD29585.1ABC transporter, permease protein, putative. (219 aa)
ABD29586.1ABC transporter, substrate-binding protein, putative; Belongs to the nlpA lipoprotein family. (280 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
ABD29751.1Iron compound ABC transporter, substrate-binding protein, putative. (275 aa)
ABD29752.1Conserved hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (316 aa)
ABD29770.1ABC transporter, substrate-binding protein, putative; Belongs to the bacterial solute-binding protein 9 family. (312 aa)
ABD29771.1Iron (chelated) ABC transporter, permease protein, putative. (278 aa)
ABD29772.1Conserved hypothetical protein. (247 aa)
ABD29773.1Conserved hypothetical protein. (214 aa)
tagHTeichoic acid translocation ATP-binding protein, putative; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system. (264 aa)
ABD29777.1Teichoic acid biosynthesis protein, putative. (270 aa)
ABD29782.1Conserved hypothetical protein. (575 aa)
ABD29786.1Iron compound ABC transporter, ATP-binding protein. (265 aa)
ABD29787.1Ferrichrome transport permease fhuB, putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (334 aa)
ABD29788.1Ferrichrome ABC transporter (permease), putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (338 aa)
ABD29800.1ABC transporter ATP-binding protein, putative. (253 aa)
ABD29801.1ABC transporter permease, putative. (629 aa)
ABD29825.1Conserved hypothetical protein. (543 aa)
ABD29826.1Conserved hypothetical protein. (557 aa)
ABD29862.1ABC transporter, ATP-binding protein. (627 aa)
ABD29864.1ABC transporter domain protein. (325 aa)
ABD29865.1Amino acid ABC transporter, permease protein, putative. (504 aa)
metN2ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)
ABD29969.1Conserved hypothetical protein. (231 aa)
ABD29970.1Conserved hypothetical protein; Belongs to the nlpA lipoprotein family. (273 aa)
ABD30048.1Conserved hypothetical protein. (308 aa)
ABD30049.1Conserved hypothetical protein. (356 aa)
ABD30050.1Conserved hypothetical protein; Belongs to the ABC transporter superfamily. (360 aa)
ABD30051.1Oligopeptide ABC transporter, ATP-binding protein, putative; Belongs to the ABC transporter superfamily. (313 aa)
ABD30052.1Oligopeptide ABC transporter, substrate-binding protein, putative. (551 aa)
ABD30095.1ABC transporter, ATP-binding protein, putative. (213 aa)
ABD30101.1Conserved hypothetical protein. (287 aa)
fmtAFmt protein, putative; Catalyzes the liberation of D-alanyl moieties present on wall teichoic acid (WTA) and lipoteichoic acid (LTA) (By similarity). Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure. (397 aa)
ABD30141.1Conserved hypothetical protein. (268 aa)
ABD30142.1Conserved hypothetical protein. (466 aa)
potAABC transporter domain protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (364 aa)
ABD30167.1Spermidine/putrescine ABC transporter, permease protein, putative. (265 aa)
ABD30168.1Spermidine/putrescine ABC transporter, permease protein, putative. (269 aa)
ABD30169.1Spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein, putative. (357 aa)
isdEConserved hypothetical protein; Involved in heme (porphyrin) scavenging. Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme. Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors to the probable permease IsdF; Belongs to the bacterial solute-binding protein 8 family. (282 aa)
isdFIron compound ABC transporter, permease protein, putative; Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane (Probable). (258 aa)
ABD30202.1Iron compound ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (97 aa)
ABD30385.1Conserved hypothetical protein. (122 aa)
ABD30409.1ABC transporter, ATP-binding protein, putative. (302 aa)
ABD30410.1Conserved hypothetical protein. (243 aa)
sbcCConserved hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity). Is probably part of the SOS regulon and involved in DNA recombination and repair. (947 aa)
ABD30440.1Conserved hypothetical protein. (35 aa)
pstBPhosphate ABC transporter ATP-binding protein, putative; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (283 aa)
ABD30481.1Phosphate ABC transporter, permease protein, putative. (305 aa)
ABD30482.1Conserved hypothetical protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (308 aa)
pstSPhosphate ABC transporter, periplasmic phosphate-binding protein, putative; Part of the ABC transporter complex PstSACB involved in phosphate import. (327 aa)
ABD30487.1ABC transporter, ATP-binding protein, putative. (533 aa)
ABD30731.1Conserved hypothetical protein. (287 aa)
ABD30732.1ABC transporter, putative. (261 aa)
ABD30844.1Conserved hypothetical protein. (271 aa)
ABD30963.1Conserved hypothetical protein. (211 aa)
ABD31007.1Membrane protein, putative. (232 aa)
ABD31008.1Membrane protein, putative. (253 aa)
ABD31009.1ABC transporter domain protein. (230 aa)
ABD31027.1ABC transporter, ATP-binding protein, putative. (246 aa)
ABD31049.1Amino acid ABC transporter, ATP-binding protein, putative. (242 aa)
ABD31050.1ABC transporter, permease protein, putative. (485 aa)
ABD31059.1ABC transporter, ATP-binding/permease protein, putative; May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity); Belongs to the ABC transporter superfamily. (578 aa)
ABD31064.1Conserved hypothetical protein. (278 aa)
ABD31065.1Conserved hypothetical protein. (505 aa)
ABD31199.1Conserved hypothetical protein. (246 aa)
ABD31200.1ABC transporter, ATP-binding protein, putative. (290 aa)
ABD31202.1ABC transporter, ATP-binding protein, putative. (298 aa)
ABD31286.1Conserved hypothetical protein. (303 aa)
ABD31295.1Abortive infection protein. (247 aa)
ABD31312.1ABC transporter, ATP-binding protein, putative. (642 aa)
ABD31427.1ABC transporter, ATP-binding protein, putative. (260 aa)
ABD31451.1Conserved hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (322 aa)
ABD31452.1Conserved hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (343 aa)
ABD31453.1ABC transporter periplasmic binding protein, putative. (327 aa)
ecfTCobalt transport protein, putative; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (268 aa)
ecfA2ABC transporter, ATP-binding protein, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (286 aa)
ecfA1ABC transporter, ATP-binding protein, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (269 aa)
ABD31560.1Molybdenum transport ATP-binding protein ModC, putative. (201 aa)
ABD31561.1Molybdenum ABC transporter, permease protein, putative; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (223 aa)
ABD31562.1Molybdenum ABC transporter, periplasmic molybdate-binding protein. (260 aa)
ABD31565.1Conserved hypothetical protein. (184 aa)
ABD31567.1Conserved hypothetical protein. (302 aa)
ABD31598.1Conserved hypothetical protein. (245 aa)
lyrAConserved hypothetical protein; Belongs to the LyrA family. (419 aa)
ABD31627.1Conserved hypothetical protein. (410 aa)
ABD31628.1Conserved hypothetical protein. (299 aa)
hrtAConserved hypothetical protein; Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system (By similarity). (221 aa)
hrtBPermease, putative domain protein; Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity). (351 aa)
ABD31666.1Membrane protein, putative. (425 aa)
ABD31698.1Conserved hypothetical protein; Belongs to the bacterial solute-binding protein 9 family. (516 aa)
ABD31705.1Amino acid ABC transporter, ATP-binding protein, putative. (243 aa)
ABD31706.1Amino acid ABC transproter, permease protein, putative. (239 aa)
ABD31707.1Conserved hypothetical protein. (259 aa)
ABD31726.1Conserved hypothetical protein. (577 aa)
ABD31727.1Conserved hypothetical protein. (587 aa)
flpConserved hypothetical protein; Its precise function is unknown. Has no penicillin-binding activity and is not involved in methicillin resistance. (498 aa)
ABD31747.1Amino acid ABC transporter, permease protein, putative. (231 aa)
ABD31748.1Amino acid transporter, putative. (313 aa)
ABD31749.1Amino acid ABC transporter, permease protein, putative. (211 aa)
ABD31750.1Amino acid ABC transporter, ATP-binding protein, putative. (408 aa)
ABD31758.1ABC transporter, ATP-binding protein, putative. (220 aa)
ABD31765.1Conserved hypothetical protein. (249 aa)
cntFPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for energy coupling to the transport system. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro. (249 aa)
cntDPeptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for energy coupling to the transport system. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro. (271 aa)
cntCNickel ABC transporter, permease protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro ; Belongs to the binding-protein-dependent transport system permease family. (289 aa)
cntBPeptide ABC transporter, permease protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro ; Belongs to the binding-protein-dependent transport system permease family. (311 aa)
cntAPeptide ABC transporter, peptide-binding protein, putative; Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Binds the metal via the metallophore StP, and transfers the StP-metal complex to the membrane-bound permease. Binds one molecule of StP/metal. Binds StP/Co(2+) and StP/Ni(2+) tighter than StP/Zn(2+). Plays a major role in nickel/cobalt import in zinc- depleted conditions. Contributes to virulence. Required for ful [...] (532 aa)
ABD31822.1Conserved hypothetical protein. (231 aa)
ABD31823.1Membrane spanning protein, putative. (256 aa)
ABD31834.1Conserved hypothetical protein. (211 aa)
ABD31835.1Conserved hypothetical protein. (243 aa)
ABD31944.1Permease, putative domain protein. (666 aa)
ABD31945.1ABC transporter, ATP-binding protein, putative. (251 aa)
isaBConserved hypothetical protein; Belongs to the IsaB family. (175 aa)
ABD31966.1Phage infection protein, putative. (993 aa)
ABD32004.1Conserved hypothetical protein. (277 aa)
ABD32005.1ABC transporter, ATP-binding protein, putative. (570 aa)
ABD32021.1ABC transporter, ATP-binding protein, putative. (252 aa)
ABD32022.1Permease, putative. (626 aa)
ABD29255.1Lipoprotein, SirC, putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (304 aa)
ABD29256.1Lipoprotein, SirB, putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (331 aa)
ABD29257.1Periplasmic binding protein, putative. (330 aa)
ABD29283.1Phosphonates ABC transporter, permease protein CC0363, putative. (271 aa)
ABD29284.1Phosphonates ABC transporter, permease protein CC0363, putative. (266 aa)
phnCAmino acid ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (257 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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