STRINGSTRING
ABD30817.1 ABD30817.1 ABD30833.1 ABD30833.1 yidC yidC ABD31492.1 ABD31492.1 secY secY ABD31657.1 ABD31657.1 clpL clpL secY2 secY2 secA2 secA2 tarK tarK tarF tarF tarL tarL tatC tatC tatA tatA ABD29635.1 ABD29635.1 clpC clpC secE secE tarB tarB secA1 secA1 ABD29929.1 ABD29929.1 clpB clpB ABD30293.1 ABD30293.1 ftsY ftsY ffh ffh ABD30716.1 ABD30716.1 ABD30717.1 ABD30717.1 ABD30718.1 ABD30718.1 ABD30719.1 ABD30719.1 secD secD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABD30817.1Preprotein translocase, YajC subunit. (86 aa)
ABD30833.1Conserved hypothetical protein. (235 aa)
yidCConserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. (290 aa)
ABD31492.1Conserved hypothetical protein. (378 aa)
secYPreprotein translocase, SecY subunit, putative; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (430 aa)
ABD31657.1Conserved hypothetical protein. (557 aa)
clpLATP-dependent Clp protease, ATP-binding subunit ClpC, putative; Required for the development of induced thermotolerance and intracellular multiplication within bovine mammary epithelial cells. (701 aa)
secY2Conserved hypothetical protein; The central subunit of a protein translocation channel (Potential). Part of the accessory SecA2/SecY2 system specifically required to export SraP, a serine-rich repeat cell wall protein encoded upstream in the same operon; Belongs to the SecY/SEC61-alpha family. SecY2 subfamily. (403 aa)
secA2Preprotein translocase, SecA subunit, putative; Part of the accessory SecA2/SecY2 system specifically required to export SraP, a serine-rich repeat cell wall protein encoded upstream in the same operon. (796 aa)
tarKtagB protein, putative; Can catalyze the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit; Belongs to the CDP-glycerol glycerophosphotransferase family. (513 aa)
tarFTeichoic acid biosynthesis protein F, putative; Catalyzes the addition of a second glycerol phosphate unit from CDP-glycerol to the prenolpyrophosphate-linked disaccharide, to complete the linkage unit. (389 aa)
tarLConserved hypothetical protein; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit. Synthesizes polymers of more than 40 ribitol phosphate units in length; Belongs to the CDP-glycerol glycerophosphotransferase family. (562 aa)
tatCConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (218 aa)
tatAmttA/Hcf106 family protein-related protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (74 aa)
ABD29635.1Conserved hypothetical protein. (130 aa)
clpCEndopeptidase, putative; Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat-denatured proteins for degradation by ClpP. Required for biofilm formation. May act as a chaperone regulating CtsR activity. (818 aa)
secEPreprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (72 aa)
tarBtagB protein, putative; Catalyzes the addition of a single glycerol phosphate residue to the prenoldiphosphate-linked disaccharide. Belongs to the CDP-glycerol glycerophosphotransferase family. (367 aa)
secA1Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (843 aa)
ABD29929.1Preprotein translocase, SecG subunit; Subunit of the protein translocation channel SecYEG (By similarity). While not essential, it considerably increases the export efficiency of extracellular proteins; Belongs to the SecG family. (91 aa)
clpBATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (869 aa)
ABD30293.1Conserved hypothetical protein. (247 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (416 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (455 aa)
ABD30716.1Conserved hypothetical protein. (148 aa)
ABD30717.1Conserved hypothetical protein; Required for transformation and DNA binding. (103 aa)
ABD30718.1Conserved hypothetical protein. (306 aa)
ABD30719.1Conserved hypothetical protein. (324 aa)
secDProtein-export membrane protein SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (739 aa)
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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