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| | ttuC | Putative tartrate dehydrogenase/decarboxylase TtuC. (358 aa) |
| | dld | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa) |
| | ALC04622.1 | Hypothetical protein. (173 aa) |
| | ALC04623.1 | Mannitol 2-dehydrogenase. (507 aa) |
| | ALC04624.1 | Permease. (444 aa) |
| | ALC04625.1 | DeoR family sugar metabolism transcriptional regulator. (284 aa) |
| | xylB | Xylulose kinase. (460 aa) |
| | ALC04643.1 | Hypothetical protein. (211 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (616 aa) |
| | adhA | Putative formaldehyde dehydrogenase AdhA. (356 aa) |
| | lpd | Dihydrolipoyl dehydrogenase. (469 aa) |
| | ALC04875.1 | Hypothetical protein. (257 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit. (674 aa) |
| | ALC04877.1 | Succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (249 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (230 aa) |
| | gabT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family. (453 aa) |
| | icd | Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (738 aa) |
| | ALC05155.1 | Carboxylate-amine ligase. (394 aa) |
| | lpdA | NAD(P)H dehydrogenase (quinone). (469 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1157 aa) |
| | prpD1 | 2-methylcitrate dehydratase 1. (501 aa) |
| | prpB1 | Putative methylisocitrate lyase 1; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (305 aa) |
| | prpC1 | 2-methylcitrate synthase 1; Belongs to the citrate synthase family. (380 aa) |
| | gltA | Citrate synthase; Belongs to the citrate synthase family. (437 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (540 aa) |
| | ALC05304.1 | Putative succinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family. (483 aa) |
| | ALC05353.1 | Hypothetical protein. (268 aa) |
| | ALC05371.1 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa) |
| | glpX | Fructose-1,6-bisphosphatase class 2. (335 aa) |
| | ALC05474.1 | Hypothetical protein. (352 aa) |
| | ALC05517.1 | Hypothetical protein; Belongs to the glycosyl hydrolase 32 family. (495 aa) |
| | odhA | 2-oxoglutarate dehydrogenase E1/E2 component. (1229 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (613 aa) |
| | ilvB | Acetolactate synthase large subunit. (626 aa) |
| | ilvH | Acetolactate synthase 3 regulatory subunit. (172 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (340 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (481 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa) |
| | ptsG | PTS system glucose-specific EIIBCA component. (675 aa) |
| | rbsK | Sugar kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (307 aa) |
| | ALC05819.1 | 6-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa) |
| | acn | Aconitate hydratase. (957 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (360 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (513 aa) |
| | ALC05982.1 | Hypothetical protein. (319 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (927 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (405 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa) |
| | ppgK | Polyphosphate glucokinase. (250 aa) |
| | ALC06119.1 | Hypothetical protein. (259 aa) |
| | ALC06120.1 | Hypothetical protein. (321 aa) |
| | ptsI | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (569 aa) |
| | ALC06122.1 | Hypothetical protein. (260 aa) |
| | ALC06123.1 | Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (330 aa) |
| | ALC06124.1 | Phosphotransferase system, fructose-specific IIC component. (694 aa) |
| | ALC06125.1 | Hypothetical protein. (89 aa) |
| | mqo | Putative malate:quinone oxidoreductase. (500 aa) |
| | mtr | Mycothione reductase. (465 aa) |
| | ALC06254.1 | Hypothetical protein. (94 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (463 aa) |
| | ALC06367.1 | Glucose kinase. (320 aa) |
| | ilvE | Branched-chain-amino-acid aminotransferase. (367 aa) |
| | aceF | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (687 aa) |
| | lipB | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (263 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (348 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (922 aa) |
| | ALC06434.1 | Hypothetical protein. (109 aa) |
| | rbsK-2 | Sugar kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (301 aa) |
| | ALC06491.1 | Hypothetical protein. (255 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (737 aa) |
| | aceA | Isocitrate lyase. (431 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (323 aa) |
| | rpiB | Ribose-5-phosphate isomerase B. (157 aa) |
| | ALC06616.1 | Gluconate kinase. (167 aa) |
| | sucD | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | sucC | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (415 aa) |
| | cat1 | Succinyl-CoA:coenzyme A transferase. (502 aa) |
| | ALC06725.1 | Hypothetical protein. (251 aa) |
| | ALC06726.1 | Hypothetical protein. (343 aa) |
| | poxB | Pyruvate dehydrogenase [ubiquinone]; Belongs to the TPP enzyme family. (579 aa) |
| | ALC06734.1 | HAD superfamily hydrolase. (271 aa) |
| | ALC06749.1 | Phosphotransferase system IIC component. (659 aa) |
| | ALC06750.1 | Hypothetical protein. (429 aa) |
| | gabD2 | Putative succinate-semialdehyde dehydrogenase [NADP(+)]; Belongs to the aldehyde dehydrogenase family. (521 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | pta | Phosphate acetyltransferase. (461 aa) |
| | fba | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa) |
| | aldA | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | adh | Alcohol dehydrogenase. (345 aa) |
| | ALC06896.1 | Hypothetical protein. (294 aa) |
| | abgA | 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (472 aa) |
| | ALC06898.1 | Hypothetical protein. (628 aa) |
| | aspC | Putative aspartate aminotransferase. (437 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (646 aa) |
| | ALC06977.1 | Pyruvate kinase. (618 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (314 aa) |
| | lldD | Putative L-lactate dehydrogenase [cytochrome]. (420 aa) |
| | ALC07035.1 | Major facilitator superfamily protein. (454 aa) |
| | ALC07036.1 | Short-chain dehydrogenase/reductase SDR. (260 aa) |
| | ALC07037.1 | Putative uncharacterized transketolase family protein y4mO. (298 aa) |
| | ALC07038.1 | Putative uncharacterized transketolase family protein y4mN. (333 aa) |
| | ALC07039.1 | Hypothetical protein. (498 aa) |
| | ALC07040.1 | Hypothetical protein. (142 aa) |
| | ALC07041.1 | Hypothetical protein. (153 aa) |
| | ALC07042.1 | Hypothetical protein. (109 aa) |
| | ALC07043.1 | PTS system transporter subunit IIC. (369 aa) |
| | alsE | D-allulose-6-phosphate 3-epimerase. (237 aa) |
| | ALC07053.1 | NAD-dependent malic enzyme. (392 aa) |
| | ALC07054.1 | Hypothetical protein. (494 aa) |
| | ALC07058.1 | Putative pyridine nucleotide-disulfide oxidoreductase. (435 aa) |
| | ALC07110.1 | Hypothetical protein. (187 aa) |
