STRINGSTRING
ALC04593.1 ALC04593.1 rmpA rmpA ALC04643.1 ALC04643.1 iolA iolA katA katA katE katE lpd lpd ALC04875.1 ALC04875.1 sdhA sdhA ALC04877.1 ALC04877.1 gpmA gpmA folD folD icd icd pyc pyc bccA bccA ALC05169.1 ALC05169.1 ALC05170.1 ALC05170.1 serC serC gltA gltA pgi pgi ALC05371.1 ALC05371.1 prs prs eno eno glyA glyA fumC fumC glpX glpX ALC05573.1 ALC05573.1 pfkA pfkA serA serA iolA2 iolA2 ALC05819.1 ALC05819.1 acn acn tkt tkt tal tal zwf zwf pgl pgl ppc ppc tpiA tpiA pgk pgk gap gap rpe rpe sdaA sdaA ppgK ppgK mqo mqo pyk pyk ilvA ilvA ALC06354.1 ALC06354.1 ALC06367.1 ALC06367.1 aceF aceF aceE aceE glcB glcB aceA aceA mdh mdh ALC06551.1 ALC06551.1 rpiB rpiB ALC06616.1 ALC06616.1 serB serB cysK1 cysK1 cysE cysE sucD sucD sucC sucC cat1 cat1 ALC06754.1 ALC06754.1 ackA ackA pta pta fba fba ALC06977.1 ALC06977.1 ALC07037.1 ALC07037.1 ALC07038.1 ALC07038.1 ALC07053.1 ALC07053.1 ALC07054.1 ALC07054.1 ALC07110.1 ALC07110.1 thlA thlA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALC04593.16-phospho 3-hexuloisomerase. (192 aa)
rmpA3-hexulose-6-phosphate synthase. (218 aa)
ALC04643.1Hypothetical protein. (211 aa)
iolAMethylmalonate semialdehyde dehydrogenase [acylating]. (504 aa)
katACatalase. (516 aa)
katECatalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide. (720 aa)
lpdDihydrolipoyl dehydrogenase. (469 aa)
ALC04875.1Hypothetical protein. (257 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (674 aa)
ALC04877.1Succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (249 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
folDBifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
icdIsocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (738 aa)
pycPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1157 aa)
bccAAcetyl-/propionyl-coenzyme A carboxylase alpha chain. (590 aa)
ALC05169.1Putative propionyl-CoA carboxylase beta chain 5. (537 aa)
ALC05170.1Putative propionyl-CoA carboxylase beta chain 5. (543 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (391 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (437 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (540 aa)
ALC05371.1Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa)
glpXFructose-1,6-bisphosphatase class 2. (335 aa)
ALC05573.1Hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
serAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
iolA2Methylmalonate semialdehyde dehydrogenase [acylating] 2. (513 aa)
ALC05819.16-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
acnAconitate hydratase. (957 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (360 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (513 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (927 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (405 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa)
sdaAL-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (449 aa)
ppgKPolyphosphate glucokinase. (250 aa)
mqoPutative malate:quinone oxidoreductase. (500 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (463 aa)
ilvAL-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (436 aa)
ALC06354.1Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. (326 aa)
ALC06367.1Glucose kinase. (320 aa)
aceFDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (687 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (922 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (737 aa)
aceAIsocitrate lyase. (431 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (323 aa)
ALC06551.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
rpiBRibose-5-phosphate isomerase B. (157 aa)
ALC06616.1Gluconate kinase. (167 aa)
serBPhosphoserine phosphatase. (434 aa)
cysK1O-acetylserine sulfhydrylase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
cysESerine O-acetyltransferase. (208 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (415 aa)
cat1Succinyl-CoA:coenzyme A transferase. (502 aa)
ALC06754.1Transcriptional regulator. (303 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ptaPhosphate acetyltransferase. (461 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
ALC06977.1Pyruvate kinase. (618 aa)
ALC07037.1Putative uncharacterized transketolase family protein y4mO. (298 aa)
ALC07038.1Putative uncharacterized transketolase family protein y4mN. (333 aa)
ALC07053.1NAD-dependent malic enzyme. (392 aa)
ALC07054.1Hypothetical protein. (494 aa)
ALC07110.1Hypothetical protein. (187 aa)
thlAAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Your Current Organism:
Corynebacterium deserti
NCBI taxonomy Id: 931089
Other names: C. deserti GIMN1.010, Corynebacterium deserti GIMN1.010, Corynebacterium sp. GIMN1.010
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