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FEN1 FEN1 G8JNE9_ERECY G8JNE9_ERECY I6NE69_ERECY I6NE69_ERECY I6NDK3_ERECY I6NDK3_ERECY G8JPT1_ERECY G8JPT1_ERECY G8JSM9_ERECY G8JSM9_ERECY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (430 aa)
G8JNE9_ERECYUncharacterized protein. (395 aa)
I6NE69_ERECYDNA polymerase. (1092 aa)
I6NDK3_ERECYRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (306 aa)
G8JPT1_ERECYRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (351 aa)
G8JSM9_ERECYUncharacterized protein. (462 aa)
Your Current Organism:
Eremothecium cymbalariae
NCBI taxonomy Id: 931890
Other names: E. cymbalariae DBVPG#7215, Eremothecium cymbalariae DBVPG#7215
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