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FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (430 aa) | ||||
G8JNE9_ERECY | Uncharacterized protein. (395 aa) | ||||
I6NE69_ERECY | DNA polymerase. (1092 aa) | ||||
I6NDK3_ERECY | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (306 aa) | ||||
G8JPT1_ERECY | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (351 aa) | ||||
G8JSM9_ERECY | Uncharacterized protein. (462 aa) |