STRINGSTRING
G8JUT3_ERECY G8JUT3_ERECY G8JM59_ERECY G8JM59_ERECY G8JMK8_ERECY G8JMK8_ERECY PIF1 PIF1 MCM7 MCM7 G8JN02_ERECY G8JN02_ERECY G8JNF6_ERECY G8JNF6_ERECY G8JNH4_ERECY G8JNH4_ERECY G8JNJ0_ERECY G8JNJ0_ERECY G8JNL8_ERECY G8JNL8_ERECY G8JNW3_ERECY G8JNW3_ERECY G8JNZ2_ERECY G8JNZ2_ERECY G8JPR8_ERECY G8JPR8_ERECY G8JPU2_ERECY G8JPU2_ERECY G8JPV4_ERECY G8JPV4_ERECY G8JQ25_ERECY G8JQ25_ERECY G8JQ58_ERECY G8JQ58_ERECY G8JQL1_ERECY G8JQL1_ERECY G8JQR1_ERECY G8JQR1_ERECY G8JQR7_ERECY G8JQR7_ERECY G8JQY1_ERECY G8JQY1_ERECY G8JR20_ERECY G8JR20_ERECY G8JR54_ERECY G8JR54_ERECY G8JRA9_ERECY G8JRA9_ERECY G8JRS4_ERECY G8JRS4_ERECY G8JRV8_ERECY G8JRV8_ERECY G8JSC7_ERECY G8JSC7_ERECY G8JSQ1_ERECY G8JSQ1_ERECY G8JSV5_ERECY G8JSV5_ERECY G8JT78_ERECY G8JT78_ERECY G8JT96_ERECY G8JT96_ERECY G8JTB6_ERECY G8JTB6_ERECY G8JTI7_ERECY G8JTI7_ERECY G8JTU1_ERECY G8JTU1_ERECY G8JUQ7_ERECY G8JUQ7_ERECY G8JUD9_ERECY G8JUD9_ERECY G8JUB1_ERECY G8JUB1_ERECY G8JU10_ERECY G8JU10_ERECY I6NE21_ERECY I6NE21_ERECY G8JXX5_ERECY G8JXX5_ERECY G8JXQ9_ERECY G8JXQ9_ERECY RRM3 RRM3 G8JW54_ERECY G8JW54_ERECY G8JVM1_ERECY G8JVM1_ERECY G8JV74_ERECY G8JV74_ERECY G8JV32_ERECY G8JV32_ERECY G8JUV4_ERECY G8JUV4_ERECY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G8JUT3_ERECYUncharacterized protein. (1072 aa)
G8JM59_ERECYRMI1_N domain-containing protein. (233 aa)
G8JMK8_ERECYZinc-hook domain-containing protein. (1298 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (884 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (813 aa)
G8JN02_ERECYDNA helicase; Belongs to the MCM family. (1025 aa)
G8JNF6_ERECYSld5 domain-containing protein. (186 aa)
G8JNH4_ERECYUncharacterized protein. (1394 aa)
G8JNJ0_ERECYRuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (467 aa)
G8JNL8_ERECYDNA helicase; Belongs to the MCM family. (890 aa)
G8JNW3_ERECYUncharacterized protein. (919 aa)
G8JNZ2_ERECYUncharacterized protein. (280 aa)
G8JPR8_ERECYUncharacterized protein. (737 aa)
G8JPU2_ERECYKu domain-containing protein. (611 aa)
G8JPV4_ERECYUncharacterized protein. (465 aa)
G8JQ25_ERECYUncharacterized protein. (716 aa)
G8JQ58_ERECYERCC4 domain-containing protein. (610 aa)
G8JQL1_ERECYHelicase ATP-binding domain-containing protein. (756 aa)
G8JQR1_ERECYMCM domain-containing protein; Belongs to the MCM family. (965 aa)
G8JQR7_ERECYDNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (290 aa)
G8JQY1_ERECYDNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (660 aa)
G8JR20_ERECYUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
G8JR54_ERECYDNA helicase; Belongs to the MCM family. (774 aa)
G8JRA9_ERECYUncharacterized protein. (1101 aa)
G8JRS4_ERECYUncharacterized protein. (1482 aa)
G8JRV8_ERECYHelicase ATP-binding domain-containing protein. (663 aa)
G8JSC7_ERECYKu domain-containing protein. (597 aa)
G8JSQ1_ERECYFHA domain-containing protein. (798 aa)
G8JSV5_ERECYUncharacterized protein. (853 aa)
G8JT78_ERECYDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (638 aa)
G8JT96_ERECYRuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (461 aa)
G8JTB6_ERECYHMG box domain-containing protein. (250 aa)
G8JTI7_ERECYUncharacterized protein. (629 aa)
G8JTU1_ERECYStructural maintenance of chromosomes protein. (1170 aa)
G8JUQ7_ERECYUncharacterized protein. (584 aa)
G8JUD9_ERECYUncharacterized protein. (1185 aa)
G8JUB1_ERECYDNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (212 aa)
G8JU10_ERECYUncharacterized protein. (1011 aa)
I6NE21_ERECYUncharacterized protein. (1497 aa)
G8JXX5_ERECYUncharacterized protein. (722 aa)
G8JXQ9_ERECYDNA helicase; Belongs to the MCM family. (882 aa)
RRM3ATP-dependent DNA helicase RRM3; 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein- DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G- quadruplex (G4) unwindi [...] (730 aa)
G8JW54_ERECYUncharacterized protein. (759 aa)
G8JVM1_ERECYUncharacterized protein. (2019 aa)
G8JV74_ERECYReplication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (620 aa)
G8JV32_ERECYUncharacterized protein. (915 aa)
G8JUV4_ERECYSld5 domain-containing protein. (203 aa)
Your Current Organism:
Eremothecium cymbalariae
NCBI taxonomy Id: 931890
Other names: E. cymbalariae DBVPG#7215, Eremothecium cymbalariae DBVPG#7215
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