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| | psdht | Serine/threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | serB | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | ydjH | 2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa) |
| | lpdG | Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa) |
| | sucB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (422 aa) |
| | sucA | SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (951 aa) |
| | hcl_1 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa) |
| | ANC43131.1 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa) |
| | leuA_1 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | ilvH | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | ilvI | Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa) |
| | acsA_1 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa) |
| | acnB | Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (861 aa) |
| | prpB_1 | 2-methylisocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa) |
| | glxK | Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (383 aa) |
| | prpD | 2-methylcitrate dehydratase; Functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa) |
| | mii_1 | 3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa) |
| | citB | Fe/S-dependent 2-methylisocitrate dehydratase AcnD; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa) |
| | prpC | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa) |
| | prpB | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (292 aa) |
| | ilvD_1 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (581 aa) |
| | scpC | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa) |
| | ghrA_1 | Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | ltaE | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (349 aa) |
| | ifcA_1 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa) |
| | hacB | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LeuD family. (190 aa) |
| | dmdA | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa) |
| | glmM | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (447 aa) |
| | prpE | EmrB/QacA subfamily drug resistance transporter; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa) |
| | icd_1 | Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (746 aa) |
| | gdhB | NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1744 aa) |
| | leuC_1 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (668 aa) |
| | fbp_1 | Fructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (337 aa) |
| | betB_2 | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (504 aa) |
| | Hgd_1 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | ANC46992.1 | Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1018 aa) |
| | ANC43590.1 | Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa) |
| | gabD-2 | Succinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa) |
| | lldD | Alpha-hydroxy-acid oxidizing enzyme; Flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa) |
| | fda | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | pykA | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (477 aa) |
| | pgk | Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (401 aa) |
| | dapL_2 | Alanine transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | maeB_1 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa) |
| | icd_2 | Isocitrate dehydrogenase (NADP(+)); Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa) |
| | ANC47065.1 | 2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa) |
| | ANC43968.1 | Glycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa) |
| | glcE | Glycolate oxidase subunit GlcE; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa) |
| | A6P55_07245 | Rieske (2Fe-2S) protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa) |
| | ghrB_1 | D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa) |
| | lutC | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa) |
| | ANC44056.1 | Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (107 aa) |
| | ANC47085.1 | Glycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa) |
| | glcE-2 | Glycolate oxidase subunit GlcE; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa) |
| | glcF | Glycolate oxidase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa) |
| | Hgd_2 | 3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (309 aa) |
| | mmsA_1 | Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa) |
| | aceE | Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (892 aa) |
| | aceE_2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (366 aa) |
| | sucD_2 | succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa) |
| | sucC | succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | gapA | Erythrose-4-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | tktA | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (670 aa) |
| | maeB_2 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (767 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa) |
| | gph_1 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (238 aa) |
| | glmS_1 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa) |
| | ifcA_2 | Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa) |
| | gltD | Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa) |
| | gltB_1 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1551 aa) |
| | ANC44517.1 | Indolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; Derived by automated computational analysis using gene prediction method: Protein Homology. (1188 aa) |
| | maeB_3 | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malic enzymes family. (759 aa) |
| | ygbM | Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (262 aa) |
| | sdaA | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (467 aa) |
| | gcvP | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (975 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvT_1 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa) |
| | mmsA_2 | Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa) |
| | fumC | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa) |
| | ANC44688.1 | Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1201 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (726 aa) |
| | ghrB_2 | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (623 aa) |
| | mdlC_1 | Benzoylformate decarboxylase; Catalyzes the formation of benzaldehyde from benzoylformate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (542 aa) |
| | xylC_2 | Salicylaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (489 aa) |
| | yhjE_3 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa) |
| | ANC44951.1 | Omega amino acid--pyruvate aminotransferase; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa) |
| | mmsA_3 | Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (453 aa) |
| | glmS_3 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa) |
| | ghrA_2 | Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | Hgd_3 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | manX | PTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa) |
| | crh | Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa) |
| | ptsI | Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (578 aa) |
| | gpmA | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa) |
| | thrC_2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (395 aa) |
| | ANC45141.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (317 aa) |
| | prs_2 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | hprK | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (321 aa) |
| | ptsN | PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa) |
| | ANC45194.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (229 aa) |
| | gcvT_2 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (829 aa) |
| | phnW_2 | 2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (377 aa) |
| | phnA | Phosphonoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa) |
| | gapN | Phosphonoacetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (484 aa) |
| | ANC47276.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa) |
| | ANC47277.1 | Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | ltaA | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa) |
| | ilvE | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | ghrB_3 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (302 aa) |
| | ANC45279.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa) |
| | lutB_1 | 4Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa) |
| | lutA_2 | Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | glcA | L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (565 aa) |
| | ANC45284.1 | Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (401 aa) |
| | leuA_2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (570 aa) |
| | ANC45305.1 | Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa) |
| | gabD_4 | NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa) |
| | dhaT | 4-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | ilvA | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (509 aa) |
| | gdhA | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (441 aa) |
| | gpmA_2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (234 aa) |
| | ghrB_4 | Bifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa) |
| | ybbH_2 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa) |
| | eda | Phosphogluconate dehydratase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa) |
| | gltB_2 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (533 aa) |
| | fumB | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | acsA_3 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa) |
| | ANC45479.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (463 aa) |
| | ANC45600.1 | Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa) |
| | gabD-3 | Succinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa) |
| | ilvD_3 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (497 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (225 aa) |
| | glk | RpiR family transcriptional regulator; Glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa) |
| | ilvB_2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (550 aa) |
| | ilvD_4 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (557 aa) |
| | ilvD_5 | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (622 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (945 aa) |
| | puuC | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (491 aa) |
| | ANC45755.1 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa) |
| | mdlB | Alpha-hydroxy-acid oxidizing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa) |
| | prpC2 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa) |
| | phnW_3 | 2-aminoethylphosphonate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (357 aa) |
| | ANC45830.1 | Phosphonopyruvate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa) |
| | pphA | Phosphoenolpyruvate phosphomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa) |
| | ANC45832.1 | ADP-glucose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | ANC45833.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | ANC47375.1 | 2OG-Fe(II) oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (274 aa) |
| | ANC45851.1 | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa) |
| | lhgO | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa) |
| | acsA_4 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa) |
| | glmS_4 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa) |
| | garR_4 | 4-hydroxybenzoyl-CoA thioesterase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | acnA | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (902 aa) |
| | mdh_2 | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa) |
| | sdhC | Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa) |
| | sdhD | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa) |
| | sdhA | Fumarate reductase (quinol) flavoprotein subunit; Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD- [...] (591 aa) |
| | sdhB | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa) |
| | ANC46185.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa) |
| | gltA | Citrate (Si)-synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cit [...] (433 aa) |
| | leuC_2 | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | leuD1 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa) |
| | aceE-2 | Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (895 aa) |
| | aceF | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (565 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa) |
| | lutA_3 | Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa) |
| | lutB_2 | (Fe-S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa) |
| | glnA | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa) |
| | talB | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa) |
| | garR_1 | 2-hydroxy-3-oxopropionate reductase; NADH-dependent; catalyzed the reversible formation of glycerate from tartronate semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | hyi | Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (263 aa) |
| | gcl | Glyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (588 aa) |
| | thrC_1 | Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa) |
| | aceA | Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa) |
| | aceB | Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (531 aa) |
| | ydiA | Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (264 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (796 aa) |
| | ANC46450.1 | NfeD-like family protein 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa) |
| | qmcA | Stomatin 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | ANC46483.1 | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (477 aa) |
| | ANC46506.1 | phytanoyl-CoA dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa) |
| | yhdH | NADPH:quinone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa) |
| | citZ | Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa) |
| | hprA | Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa) |
| | ilvB_1 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa) |
| | pgi | Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (552 aa) |
