(22 nodes) Mixed, incl. Tryptophan catabolic process, and NADPH dehydrogenase YqjM-like network (Pandoraea pnomenusa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vioD	Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
	ridA_1	Enamine deaminase RidA; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
	ANC43424.1	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
	bclA_1	2-aminobenzoate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
	ANC43426.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
	ANC43427.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (287 aa)
	actIII	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)
	namA_1	Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (780 aa)
	proP_4	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
	ANC46963.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
	hcl_2	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
	ANC43631.1	BEC protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
	ANC43632.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
	ANC43633.1	Peptidase M29; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
	C1-hpah_1	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
	ANC47000.1	MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
	kynB	Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (224 aa)
	kynU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (417 aa)
	kynA	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (318 aa)
	badR_2	MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
	namA_2	NADH:flavin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
	ANC46668.1	Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)

Your Current Organism:

Pandoraea pnomenusa

NCBI taxonomy Id: 93220
Other names: ATCC BAA-63, ATCC:BAA:63, CCM 4978, CCUG 38742, CIP 106626, DSM 16536, LMG 18087, LMG:18087, NCTC 13160, P. pnomenusa, Pandoraea pnomenusa Coenye et al. 2000, Pandoraea sp. RB-44

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANC43424.1	ANC43426.1	A6P55_03290	A6P55_03300	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.758
ANC43424.1	ANC43427.1	A6P55_03290	A6P55_03305	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.863
ANC43424.1	ANC47000.1	A6P55_03290	A6P55_04615	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436
ANC43424.1	actIII	A6P55_03290	A6P55_03310	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.693
ANC43424.1	badR_2	A6P55_03290	A6P55_08825	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.771
ANC43424.1	bclA_1	A6P55_03290	A6P55_03295	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-aminobenzoate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892
ANC43424.1	namA_1	A6P55_03290	A6P55_03315	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.856
ANC43424.1	ridA_1	A6P55_03290	A6P55_03285	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enamine deaminase RidA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.952
ANC43424.1	vioD	A6P55_03290	A6P55_02990	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
ANC43426.1	ANC43424.1	A6P55_03300	A6P55_03290	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.758
ANC43426.1	ANC43427.1	A6P55_03300	A6P55_03305	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.956
ANC43426.1	actIII	A6P55_03300	A6P55_03310	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.700
ANC43426.1	badR_2	A6P55_03300	A6P55_08825	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.652
ANC43426.1	bclA_1	A6P55_03300	A6P55_03295	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-aminobenzoate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822
ANC43426.1	hcl_2	A6P55_03300	A6P55_04590	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.562
ANC43426.1	namA_1	A6P55_03300	A6P55_03315	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.884
ANC43426.1	ridA_1	A6P55_03300	A6P55_03285	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Enamine deaminase RidA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.802
ANC43426.1	vioD	A6P55_03300	A6P55_02990	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
ANC43427.1	ANC43424.1	A6P55_03305	A6P55_03290	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.863
ANC43427.1	ANC43426.1	A6P55_03305	A6P55_03300	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956

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