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ribE ribE ANC46696.1 ANC46696.1 ANC46878.1 ANC46878.1 ANC43009.1 ANC43009.1 mdeA_1 mdeA_1 selU selU folP folP ANC43453.1 ANC43453.1 nadA nadA miaA miaA aroG aroG yvqK yvqK ubiA ubiA murA_1 murA_1 speE speE bsdB bsdB murA_2 murA_2 thiE_1 thiE_1 mdeA_2 mdeA_2 metK metK ctaB ctaB thiE_2 thiE_2 ANC45456.1 ANC45456.1 ribH ribH aroA aroA cysM cysM cobO cobO hemC hemC crtM_1 crtM_1 crtM_2 crtM_2 ANC46068.1 ANC46068.1 kdsA kdsA ANC46306.1 ANC46306.1 uppS uppS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ribERiboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
ANC46696.1CDP-alcohol phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
ANC46878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (117 aa)
ANC43009.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (294 aa)
mdeA_1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
selUtRNA 2-selenouridine(34) synthase MnmH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SelU family. (367 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (296 aa)
ANC43453.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (345 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (377 aa)
miaAtRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (315 aa)
aroGPhospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa)
yvqKCobalamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (290 aa)
murA_1UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
speEHypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (308 aa)
bsdB3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (208 aa)
murA_2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (425 aa)
thiE_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
mdeA_2O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (392 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (301 aa)
thiE_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
ANC45456.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (170 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (440 aa)
cysMCysteine synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa)
cobOcob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (212 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (322 aa)
crtM_1Squalene synthase HpnC; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
crtM_2Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ANC46068.1Spermidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (284 aa)
ANC46306.1Glutathione-dependent reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
uppSDi-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (260 aa)
Your Current Organism:
Pandoraea pnomenusa
NCBI taxonomy Id: 93220
Other names: ATCC BAA-63, ATCC:BAA:63, CCM 4978, CCUG 38742, CIP 106626, DSM 16536, LMG 18087, LMG:18087, NCTC 13160, P. pnomenusa, Pandoraea pnomenusa Coenye et al. 2000, Pandoraea sp. RB-44
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