STRINGSTRING
glnA glnA bktB_1 bktB_1 fabG_6 fabG_6 thlA_1 thlA_1 lpdG lpdG hcl_1 hcl_1 acsA_1 acsA_1 acnB acnB glxK glxK ghrA_1 ghrA_1 glyA glyA ANC43590.1 ANC43590.1 kynB kynB ANC43768.1 ANC43768.1 ANC43968.1 ANC43968.1 glcE glcE A6P55_07245 A6P55_07245 ghrB_1 ghrB_1 ANC47085.1 ANC47085.1 glcE-2 glcE-2 glcF glcF srpA srpA gph_1 gph_1 ANC44380.1 ANC44380.1 ANC44385.1 ANC44385.1 yfgD yfgD ygbM ygbM gcvP gcvP gcvH gcvH gcvT_1 gcvT_1 ANC44754.1 ANC44754.1 glcB glcB bktB_2 bktB_2 katA_1 katA_1 ANC45016.1 ANC45016.1 ghrA_2 ghrA_2 thlA_2 thlA_2 ANC45079.1 ANC45079.1 purU purU thlA_3 thlA_3 ghrB_3 ghrB_3 lutA_2 lutA_2 ANC45284.1 ANC45284.1 ANC45305.1 ANC45305.1 ghrB_4 ghrB_4 eda eda katA_2 katA_2 acsA_3 acsA_3 ANC45585.1 ANC45585.1 rlp2 rlp2 prpC2 prpC2 acsA_4 acsA_4 ANC45890.1 ANC45890.1 ANC45891.1 ANC45891.1 nuoF_2 nuoF_2 nuoE nuoE oxc oxc ANC45922.1 ANC45922.1 ANC45923.1 ANC45923.1 fdoH fdoH fdoI fdoI ANC47416.1 ANC47416.1 acnA acnA mdh_2 mdh_2 gltA gltA lpdA lpdA lutA_3 lutA_3 hyi hyi gcl gcl aceA aceA aceB aceB yffB yffB ldcA ldcA fdhF fdhF nqo2_1 nqo2_1 nuoF_1 nuoF_1 ANC46502.1 ANC46502.1 ANC46503.1 ANC46503.1 citZ citZ ANC46588.1 ANC46588.1 lip2_1 lip2_1 ANC46668.1 ANC46668.1 lip2_2 lip2_2 ANC46739.1 ANC46739.1 hprA hprA fabG_3 fabG_3 fadI fadI
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
bktB_1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
fabG_6beta-ketoacyl-ACP reductase; Catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
thlA_1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
lpdGDihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
hcl_1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
acsA_1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
acnBAconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (861 aa)
glxKGlycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (383 aa)
ghrA_1Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
ANC43590.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
kynBArylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (224 aa)
ANC43768.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
ANC43968.1Glycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
glcEGlycolate oxidase subunit GlcE; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
A6P55_07245Rieske (2Fe-2S) protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
ghrB_1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
ANC47085.1Glycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
glcE-2Glycolate oxidase subunit GlcE; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
glcFGlycolate oxidase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
srpACatalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (362 aa)
gph_1Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (238 aa)
ANC44380.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (512 aa)
ANC44385.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (307 aa)
yfgDArsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
ygbMHydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (262 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (975 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvT_1Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
ANC44754.1Formamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (726 aa)
bktB_2acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
katA_1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (489 aa)
ANC45016.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
ghrA_2Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
thlA_2acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
ANC45079.1N-formylglutamate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa)
thlA_3Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
ghrB_3Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (302 aa)
lutA_2Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
ANC45284.1Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (401 aa)
ANC45305.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
ghrB_4Bifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
edaPhosphogluconate dehydratase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
katA_2Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (482 aa)
acsA_3Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
ANC45585.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
rlp2Ribulose 1,5-bisphosphate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RuBisCO large chain family. (430 aa)
prpC2Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
acsA_4AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
ANC45890.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
ANC45891.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (966 aa)
nuoF_2Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
nuoEFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
oxcoxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (567 aa)
ANC45922.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
ANC45923.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa)
fdoHFormate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
fdoIFormate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
ANC47416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (902 aa)
mdh_2Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
gltACitrate (Si)-synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cit [...] (433 aa)
lpdADihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
lutA_3Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
hyiHydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (263 aa)
gclGlyoxylate carboligase; Catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (588 aa)
aceAIsocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
aceBMalate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (531 aa)
yffBArsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (115 aa)
ldcALD-carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
fdhFCbbBc protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (770 aa)
nqo2_1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
nuoF_1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
ANC46502.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (964 aa)
ANC46503.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
citZExcisionase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
ANC46588.1Catalase HPII; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa)
lip2_1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
ANC46668.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
lip2_2Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
ANC46739.1Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
hprAHydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
fabG_3beta-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
fadIacetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (440 aa)
Your Current Organism:
Pandoraea pnomenusa
NCBI taxonomy Id: 93220
Other names: ATCC BAA-63, ATCC:BAA:63, CCM 4978, CCUG 38742, CIP 106626, DSM 16536, LMG 18087, LMG:18087, NCTC 13160, P. pnomenusa, Pandoraea pnomenusa Coenye et al. 2000, Pandoraea sp. RB-44
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