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yrpC yrpC rluC rluC rluE rluE fkpB fkpB AJC18221.1 AJC18221.1 rmlC rmlC dmpI dmpI hemL hemL gyrA gyrA pheA pheA hldD hldD APD12705.1 APD12705.1 ycjG ycjG ygeA ygeA shc shc pphA pphA parE parE parC parC APD12504.1 APD12504.1 slyD slyD tpiA tpiA AJC19070.2 AJC19070.2 truA truA trpF trpF AJC17503.1 AJC17503.1 ppiB ppiB fbp_2 fbp_2 glnA_2 glnA_2 rsuA rsuA rpiA rpiA rluB rluB truB truB hyi hyi dadX dadX rluF rluF galE galE AJC17065.1 AJC17065.1 AJC17018.1 AJC17018.1 fadJ fadJ cbf2 cbf2 nnr nnr pgi pgi ppiD ppiD tig tig rluD rluD maiA-2 maiA-2 mii_2 mii_2 ywhB ywhB AJC16557.1 AJC16557.1 maiA maiA glmM glmM AJC16452.1 AJC16452.1 purE purE groL groL AJC18701.1 AJC18701.1 queA queA gpmA_2 gpmA_2 glnA_1 glnA_1 kdsD kdsD gpmA gpmA AJC15801.2 AJC15801.2 AJC15800.1 AJC15800.1 nahD_1 nahD_1 mii_1 mii_1 dapF dapF topB topB gyrB gyrB ygbM ygbM gmhA gmhA gmhA1 gmhA1 APD12640.1 APD12640.1 hisA hisA prsA3 prsA3 AJC15115.1 AJC15115.1 dsbC dsbC rpe rpe apaG apaG AJC15009.1 AJC15009.1 surA surA AJC14928.1 AJC14928.1 algC algC nahD_3 nahD_3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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yrpCGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (312 aa)
rluCRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (334 aa)
rluEPseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (196 aa)
fkpBPeptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
AJC18221.14-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (133 aa)
rmlCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)
dmpI4-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (69 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (873 aa)
pheAChorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
hldDADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (334 aa)
APD12705.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
ycjGDipeptide epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
ygeAAspartate/glutamate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/glutamate racemases family. (233 aa)
shcHypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
pphAPhosphoenolpyruvate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (659 aa)
parCDNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (778 aa)
APD12504.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
slyDPeptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
AJC19070.2Fructose-2,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
truAtRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (266 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (224 aa)
AJC17503.1Cyclophilin; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
ppiBPeptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (195 aa)
fbp_2Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
glnA_2Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
rsuAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (223 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa)
rluB23S rRNA pseudouridylate synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (597 aa)
truBtRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (328 aa)
hyiHydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (263 aa)
dadXAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (356 aa)
rluFHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (660 aa)
galEUDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (340 aa)
AJC17065.14-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (71 aa)
AJC17018.1Asp/Glu/hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
fadJ3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
cbf2Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
nnrHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (509 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (552 aa)
ppiDHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (446 aa)
rluDRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (386 aa)
maiA-2Asp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (249 aa)
mii_2Putative methylaconitate Delta-isomerase PrpF; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
ywhB4-oxalocrotonate tautomerase; 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (64 aa)
AJC16557.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
maiAAsp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. (250 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (447 aa)
AJC16452.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/glutamate racemases family. (242 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (168 aa)
groLChaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (548 aa)
AJC18701.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
queAtRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (360 aa)
gpmA_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (235 aa)
glnA_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (436 aa)
kdsDArabinose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily. (326 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
AJC15801.2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AJC15800.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
nahD_12-hydroxychromene-2-carboxylate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
mii_14-oxalomesaconate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (283 aa)
topBDNA topoisomerase III; Decatenates replicating daughter chromosomes; Derived by automated computational analysis using gene prediction method: Protein Homology. (902 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (825 aa)
ygbMHydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (264 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (195 aa)
gmhA1Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (190 aa)
APD12640.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
prsA3Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AJC15115.1Hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
dsbCThiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (254 aa)
rpeRibulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
apaGCo2+/Mg2+ efflux protein ApaG; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AJC15009.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (326 aa)
surAMolecular chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (452 aa)
AJC14928.14-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
algCLipopolysaccharide heptosyltransferase I; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
nahD_32-hydroxychromene-2-carboxylate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
Your Current Organism:
Pandoraea sputorum
NCBI taxonomy Id: 93222
Other names: ATCC BAA-64, ATCC:BAA:64, CCUG 45026, CIP 106624, DSM 21091, LMG 18819, LMG:18819, NCTC 13161, P. sputorum, Pandoraea sputorum Coenye et al. 2000
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