STRINGSTRING
flhA_1 flhA_1 ghrB_1 ghrB_1 gpmA gpmA AJC16019.1 AJC16019.1 eutD eutD tmd tmd gpmA_2 gpmA_2 acsA_1 acsA_1 fda fda AJC16355.1 AJC16355.1 glyA glyA fbp_1 fbp_1 acsA_3 acsA_3 bclA_3 bclA_3 serB serB AJC17223.1 AJC17223.1 AJC17225.2 AJC17225.2 nuoF nuoF nqo2_1 nqo2_1 ppsA ppsA fghA fghA mdh_2 mdh_2 eno eno fdoI fdoI fdoH fdoH NA29_20445 NA29_20445 nuoE nuoE nqo1_2 nqo1_2 AJC17771.1 AJC17771.1 AJC17772.1 AJC17772.1 acs acs ppc ppc serC serC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
flhA_1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)
ghrB_13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
AJC16019.1Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (401 aa)
eutDPhosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
tmdTrimethylamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
gpmA_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (235 aa)
acsA_1acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
fdaFructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
AJC16355.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
fbp_1Fructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (337 aa)
acsA_3AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
bclA_3AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
serBPhosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AJC17223.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
AJC17225.2Formate dehydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (966 aa)
nuoFFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
nqo2_1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (796 aa)
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa)
mdh_2Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
fdoIFormate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
fdoHFormate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
NA29_20445Formate dehydrogenase-N subunit alpha; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
nuoEFormate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
nqo1_2Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
AJC17771.1Formate dehydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (953 aa)
AJC17772.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
acsAMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (999 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (370 aa)
Your Current Organism:
Pandoraea sputorum
NCBI taxonomy Id: 93222
Other names: ATCC BAA-64, ATCC:BAA:64, CCUG 45026, CIP 106624, DSM 21091, LMG 18819, LMG:18819, NCTC 13161, P. sputorum, Pandoraea sputorum Coenye et al. 2000
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.