(36 nodes) ATPase, nucleotide binding domain network (Penicillium oxalicum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDE_09158	Uncharacterized protein. (576 aa)
	PDE_01397	Uncharacterized protein; Belongs to the actin family. (653 aa)
	PDE_00169	Uncharacterized protein; Belongs to the actin family. (388 aa)
	PDE_00429	Uncharacterized protein. (718 aa)
	PDE_00987	Uncharacterized protein; Belongs to the heat shock protein 70 family. (615 aa)
	PDE_01092	Actin. (375 aa)
	KAE1	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (366 aa)
	PDE_09168	tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (450 aa)
	PDE_08993	Uncharacterized protein; Belongs to the FGGY kinase family. (643 aa)
	PDE_06201	Uncharacterized protein; Belongs to the actin family. (471 aa)
	PDE_08312	Uncharacterized protein; Belongs to the actin family. (381 aa)
	PDE_08226	Phosphotransferase. (571 aa)
	PDE_09139	Phosphotransferase. (544 aa)
	PDE_00412	Uncharacterized protein. (999 aa)
	PDE_00019	Ppx-GppA domain-containing protein. (605 aa)
	PDE_01304	Uncharacterized protein; Belongs to the actin family. (752 aa)
	PDE_01777	Uncharacterized protein. (441 aa)
	PDE_00703	Uncharacterized protein. (724 aa)
	PDE_00878	Phosphotransferase. (545 aa)
	PDE_07538	Uncharacterized protein; Belongs to the actin family. (439 aa)
	PDE_07688	Phosphotransferase. (621 aa)
	PDE_08980	Putative Hsp70 molecular chaperone; Belongs to the heat shock protein 70 family. (672 aa)
	PDE_05413	Uncharacterized protein; Belongs to the heat shock protein 70 family. (566 aa)
	PDE_05769	Uncharacterized protein; Belongs to the actin family. (467 aa)
	PDE_08454	Uncharacterized protein; Belongs to the FGGY kinase family. (569 aa)
	PDE_03070	Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (714 aa)
	PDE_03526	Phosphotransferase. (478 aa)
	PDE_03370	Phosphotransferase. (497 aa)
	PDE_03751	Uncharacterized protein. (514 aa)
	PDE_03760	Uncharacterized protein; Belongs to the heat shock protein 70 family. (660 aa)
	PDE_02379	Uncharacterized protein; Belongs to the heat shock protein 70 family. (635 aa)
	PDE_05139	Probable acetate kinase. (414 aa)
	PDE_03592	Phosphotransferase. (490 aa)
	PDE_05792	Uncharacterized protein. (610 aa)
	PDE_06060	Uncharacterized protein. (504 aa)
	PDE_05101	Uncharacterized protein; Belongs to the actin family. (533 aa)

Your Current Organism:

Penicillium oxalicum

NCBI taxonomy Id: 933388
Other names: P. oxalicum 114-2, Penicillium oxalicum 114-2

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KAE1	PDE_09168	S7ZC00	S7ZUU2	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...]	tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.	0.483
PDE_00169	PDE_00429	S7Z985	S7Z9Z0	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.544
PDE_00169	PDE_00987	S7Z985	S7ZBI6	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.615
PDE_00169	PDE_01092	S7Z985	S7ZBT6	Uncharacterized protein; Belongs to the actin family.	Actin.	0.972
PDE_00169	PDE_01304	S7Z985	S8AKN8	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.778
PDE_00169	PDE_01397	S7Z985	S7Z7C5	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.887
PDE_00169	PDE_02379	S7Z985	S7ZFK7	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.615
PDE_00169	PDE_03751	S7Z985	S7ZDT3	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.544
PDE_00169	PDE_05101	S7Z985	S7ZN85	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.900
PDE_00169	PDE_05413	S7Z985	S8B6Z4	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.615
PDE_00169	PDE_05769	S7Z985	S8B7W8	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.527
PDE_00169	PDE_06060	S7Z985	S7ZKD9	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.544
PDE_00169	PDE_07538	S7Z985	S8B198	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.999
PDE_00169	PDE_08312	S7Z985	S7ZRM1	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.965
PDE_00412	PDE_00703	S7Z5T1	S8AV83	Uncharacterized protein.	Uncharacterized protein.	0.763
PDE_00412	PDE_03760	S7Z5T1	S7ZEW8	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.509
PDE_00412	PDE_08980	S7Z5T1	S8B581	Uncharacterized protein.	Putative Hsp70 molecular chaperone; Belongs to the heat shock protein 70 family.	0.993
PDE_00429	PDE_00169	S7Z9Z0	S7Z985	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.544
PDE_00429	PDE_00703	S7Z9Z0	S8AV83	Uncharacterized protein.	Uncharacterized protein.	0.812
PDE_00429	PDE_03760	S7Z9Z0	S7ZEW8	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.722