(19 nodes) Cytosolic small ribosomal subunit network (Edwardsiella hoshinae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpsA	30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (556 aa)
	raiA	Ribosomal subunit interface protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
	rpsP	30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family. (82 aa)
	rpsD	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)
	AOV95732.1	30S ribosomal protein S11; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
	AOV95731.1	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
	rpsE	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa)
	rpsH	30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	rpsN	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
	rpsQ	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa)
	rpsC	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (233 aa)
	rpsF	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa)
	rpsR	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa)
	AOV98066.1	30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
	rpsG	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
	rpsL	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
	rpsI	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (130 aa)
	rpsT	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa)
	rpsB	30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (241 aa)

Your Current Organism:

Edwardsiella hoshinae

NCBI taxonomy Id: 93378
Other names: ATCC 33379, CIP 78.56, DSM 13771, E. hoshinae, NBRC 105699, NCTC 12121, strain 2-78

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOV95731.1	AOV95732.1	A9798_01350	A9798_01355	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S11; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOV95731.1	AOV98066.1	A9798_01350	A9798_14635	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOV95731.1	raiA	A9798_01350	A9798_03045	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribosomal subunit interface protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.673
AOV95731.1	rpsA	A9798_01350	A9798_06160	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.	0.976
AOV95731.1	rpsB	A9798_01350	A9798_12865	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.	0.998
AOV95731.1	rpsC	A9798_01350	A9798_01275	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.999
AOV95731.1	rpsD	A9798_01350	A9798_01360	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
AOV95731.1	rpsE	A9798_01350	A9798_01330	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.999
AOV95731.1	rpsF	A9798_01350	A9798_14850	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.989
AOV95731.1	rpsG	A9798_01350	A9798_01225	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.999
AOV95731.1	rpsH	A9798_01350	A9798_01315	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.	0.999
AOV95731.1	rpsI	A9798_01350	A9798_13920	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.	0.990
AOV95731.1	rpsL	A9798_01350	A9798_01220	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.998
AOV95731.1	rpsN	A9798_01350	A9798_01310	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.	0.998
AOV95731.1	rpsP	A9798_01350	A9798_02980	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family.	0.982
AOV95731.1	rpsQ	A9798_01350	A9798_01290	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.998
AOV95731.1	rpsR	A9798_01350	A9798_14840	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.	0.986
AOV95731.1	rpsT	A9798_01350	A9798_13580	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.942
AOV95732.1	AOV95731.1	A9798_01355	A9798_01350	30S ribosomal protein S11; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S13; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOV95732.1	AOV98066.1	A9798_01355	A9798_14635	30S ribosomal protein S11; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998