(29 nodes) Homologous recombination, and DNA repair complex network (Nematocida parisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	NEQG_02607	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (853 aa)
	NEQG_02617	BRCA-2_OB1 domain-containing protein. (551 aa)
	NEQG_02384	Uncharacterized protein. (507 aa)
	NEQG_02098	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (861 aa)
	NEQG_02125	ERCC4 domain-containing protein. (699 aa)
	NEQG_02200	Atypical/PIKK/ATM protein kinase. (831 aa)
	NEQG_01921	DNA_MISMATCH_REPAIR_2 domain-containing protein. (907 aa)
	NEQG_01465	Uncharacterized protein. (869 aa)
	NEQG_01544	Uncharacterized protein. (222 aa)
	NEQG_01569	AAA_23 domain-containing protein. (983 aa)
	NEQG_01586	CAMK/CAMKL/CHK1 protein kinase. (423 aa)
	NEQG_01660	DNA mismatch repair protein MutS. (717 aa)
	NEQG_01128	DNA mismatch repair protein mlh1. (263 aa)
	NEQG_01156	Transcription elongation factor A. (164 aa)
	NEQG_01167	Uncharacterized protein. (573 aa)
	NEQG_01210	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family. (1818 aa)
	NEQG_01283	Uncharacterized protein. (213 aa)
	NEQG_01294	Uncharacterized protein. (322 aa)
	NEQG_01304	DNA repair protein RAD51; Belongs to the RecA family. (222 aa)
	NEQG_01360	ERCC4 domain-containing protein. (572 aa)
	NEQG_01416	OB domain-containing protein. (232 aa)
	NEQG_00732	Uncharacterized protein. (276 aa)
	NEQG_00855	XPA_C domain-containing protein. (181 aa)
	NEQG_00923	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (320 aa)
	NEQG_00945	Uncharacterized protein. (385 aa)
	NEQG_00968	MutL_C domain-containing protein. (625 aa)
	NEQG_00009	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (588 aa)
	NEQG_00185	Helicase ATP-binding domain-containing protein. (689 aa)
	NEQG_00422	XPGN domain-containing protein. (503 aa)

Your Current Organism:

Nematocida parisii

NCBI taxonomy Id: 935791
Other names: N. parisii ERTm3, Nematocida parisii ERTm3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEQG_00009	NEQG_00185	I3EJ42	I3EJL8	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Helicase ATP-binding domain-containing protein.	0.765
NEQG_00009	NEQG_00422	I3EJ42	I3EKA5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	XPGN domain-containing protein.	0.734
NEQG_00009	NEQG_00732	I3EJ42	I3EI66	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.928
NEQG_00009	NEQG_00945	I3EJ42	I3EIS9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.562
NEQG_00009	NEQG_00968	I3EJ42	I3EIV2	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	MutL_C domain-containing protein.	0.429
NEQG_00009	NEQG_01128	I3EJ42	I3EGU1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA mismatch repair protein mlh1.	0.482
NEQG_00009	NEQG_01167	I3EJ42	I3EGY0	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.754
NEQG_00009	NEQG_01210	I3EJ42	I3EH23	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family.	0.852
NEQG_00009	NEQG_01283	I3EJ42	I3EH96	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.497
NEQG_00009	NEQG_01294	I3EJ42	I3EHA7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.911
NEQG_00009	NEQG_01304	I3EJ42	I3EHB7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA repair protein RAD51; Belongs to the RecA family.	0.885
NEQG_00009	NEQG_01360	I3EJ42	I3EHH3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	ERCC4 domain-containing protein.	0.663
NEQG_00009	NEQG_01416	I3EJ42	I3EHM9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	OB domain-containing protein.	0.628
NEQG_00009	NEQG_01465	I3EJ42	I3EFM4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.800
NEQG_00009	NEQG_01544	I3EJ42	I3EFV3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.727
NEQG_00009	NEQG_01569	I3EJ42	I3EFX8	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	AAA_23 domain-containing protein.	0.999
NEQG_00009	NEQG_01586	I3EJ42	I3EFZ5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	CAMK/CAMKL/CHK1 protein kinase.	0.623
NEQG_00009	NEQG_01660	I3EJ42	I3EG69	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA mismatch repair protein MutS.	0.545
NEQG_00009	NEQG_01921	I3EJ42	I3EF52	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.566
NEQG_00009	NEQG_02098	I3EJ42	I3EEA4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.900