(16 nodes) Homologous recombination network (Nematocida parisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEQG_02607	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (853 aa)
	NEQG_02617	BRCA-2_OB1 domain-containing protein. (551 aa)
	NEQG_02098	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (861 aa)
	NEQG_02200	Atypical/PIKK/ATM protein kinase. (831 aa)
	NEQG_01465	Uncharacterized protein. (869 aa)
	NEQG_01544	Uncharacterized protein. (222 aa)
	NEQG_01569	AAA_23 domain-containing protein. (983 aa)
	NEQG_01586	CAMK/CAMKL/CHK1 protein kinase. (423 aa)
	NEQG_01167	Uncharacterized protein. (573 aa)
	NEQG_01210	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family. (1818 aa)
	NEQG_01304	DNA repair protein RAD51; Belongs to the RecA family. (222 aa)
	NEQG_01416	OB domain-containing protein. (232 aa)
	NEQG_00732	Uncharacterized protein. (276 aa)
	NEQG_00945	Uncharacterized protein. (385 aa)
	NEQG_00009	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (588 aa)
	NEQG_00185	Helicase ATP-binding domain-containing protein. (689 aa)

Your Current Organism:

Nematocida parisii

NCBI taxonomy Id: 935791
Other names: N. parisii ERTm3, Nematocida parisii ERTm3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEQG_00009	NEQG_00185	I3EJ42	I3EJL8	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Helicase ATP-binding domain-containing protein.	0.765
NEQG_00009	NEQG_00732	I3EJ42	I3EI66	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.928
NEQG_00009	NEQG_00945	I3EJ42	I3EIS9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.562
NEQG_00009	NEQG_01167	I3EJ42	I3EGY0	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.754
NEQG_00009	NEQG_01210	I3EJ42	I3EH23	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family.	0.852
NEQG_00009	NEQG_01304	I3EJ42	I3EHB7	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA repair protein RAD51; Belongs to the RecA family.	0.885
NEQG_00009	NEQG_01416	I3EJ42	I3EHM9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	OB domain-containing protein.	0.628
NEQG_00009	NEQG_01465	I3EJ42	I3EFM4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.800
NEQG_00009	NEQG_01544	I3EJ42	I3EFV3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.727
NEQG_00009	NEQG_01569	I3EJ42	I3EFX8	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	AAA_23 domain-containing protein.	0.999
NEQG_00009	NEQG_01586	I3EJ42	I3EFZ5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	CAMK/CAMKL/CHK1 protein kinase.	0.623
NEQG_00009	NEQG_02098	I3EJ42	I3EEA4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.900
NEQG_00009	NEQG_02200	I3EJ42	I3EEK6	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Atypical/PIKK/ATM protein kinase.	0.974
NEQG_00009	NEQG_02607	I3EJ42	I3EDH5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.735
NEQG_00009	NEQG_02617	I3EJ42	I3EDI5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	BRCA-2_OB1 domain-containing protein.	0.664
NEQG_00185	NEQG_00009	I3EJL8	I3EJ42	Helicase ATP-binding domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.765
NEQG_00185	NEQG_00732	I3EJL8	I3EI66	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.964
NEQG_00185	NEQG_00945	I3EJL8	I3EIS9	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.958
NEQG_00185	NEQG_01167	I3EJL8	I3EGY0	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.598
NEQG_00185	NEQG_01210	I3EJL8	I3EH23	Helicase ATP-binding domain-containing protein.	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family.	0.631