(5 nodes) HDR through Single Strand Annealing (SSA) network (Nematocida parisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEQG_02607	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (853 aa)
	NEQG_02098	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (861 aa)
	NEQG_01544	Uncharacterized protein. (222 aa)
	NEQG_01167	Uncharacterized protein. (573 aa)
	NEQG_01416	OB domain-containing protein. (232 aa)

Your Current Organism:

Nematocida parisii

NCBI taxonomy Id: 935791
Other names: N. parisii ERTm3, Nematocida parisii ERTm3

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEQG_01167	NEQG_01416	I3EGY0	I3EHM9	Uncharacterized protein.	OB domain-containing protein.	0.998
NEQG_01167	NEQG_01544	I3EGY0	I3EFV3	Uncharacterized protein.	Uncharacterized protein.	0.991
NEQG_01167	NEQG_02098	I3EGY0	I3EEA4	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.988
NEQG_01167	NEQG_02607	I3EGY0	I3EDH5	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.981
NEQG_01416	NEQG_01167	I3EHM9	I3EGY0	OB domain-containing protein.	Uncharacterized protein.	0.998
NEQG_01416	NEQG_01544	I3EHM9	I3EFV3	OB domain-containing protein.	Uncharacterized protein.	0.825
NEQG_01416	NEQG_02098	I3EHM9	I3EEA4	OB domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.954
NEQG_01416	NEQG_02607	I3EHM9	I3EDH5	OB domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.933
NEQG_01544	NEQG_01167	I3EFV3	I3EGY0	Uncharacterized protein.	Uncharacterized protein.	0.991
NEQG_01544	NEQG_01416	I3EFV3	I3EHM9	Uncharacterized protein.	OB domain-containing protein.	0.825
NEQG_01544	NEQG_02098	I3EFV3	I3EEA4	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.858
NEQG_01544	NEQG_02607	I3EFV3	I3EDH5	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.740
NEQG_02098	NEQG_01167	I3EEA4	I3EGY0	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	Uncharacterized protein.	0.988
NEQG_02098	NEQG_01416	I3EEA4	I3EHM9	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	OB domain-containing protein.	0.954
NEQG_02098	NEQG_01544	I3EEA4	I3EFV3	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	Uncharacterized protein.	0.858
NEQG_02098	NEQG_02607	I3EEA4	I3EDH5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.998
NEQG_02607	NEQG_01167	I3EDH5	I3EGY0	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.981
NEQG_02607	NEQG_01416	I3EDH5	I3EHM9	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	OB domain-containing protein.	0.933
NEQG_02607	NEQG_01544	I3EDH5	I3EFV3	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.740
NEQG_02607	NEQG_02098	I3EDH5	I3EEA4	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.998