(33 nodes) Nuclear outer membrane-endoplasmic reticulum membrane network network (Nematocida parisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEQG_00728	Hydrolase_4 domain-containing protein. (305 aa)
	NEQG_00546	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (235 aa)
	NEQG_00499	Ubiquitin-conjugating enzyme E2 g; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	NEQG_00482	Aminotran_1_2 domain-containing protein. (515 aa)
	NEQG_00418	Sulfhydryl oxidase. (160 aa)
	NEQG_00398	Transitional endoplasmic reticulum ATPase TER94. (792 aa)
	NEQG_00274	IRE protein kinase. (677 aa)
	NEQG_00243	Uncharacterized protein. (694 aa)
	NEQG_00242	Uncharacterized protein. (397 aa)
	NEQG_00140	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (275 aa)
	NEQG_00054	Signal peptidase complex catalytic subunit SEC11. (241 aa)
	NEQG_00016	RING-type domain-containing protein. (384 aa)
	NEQG_01010	Elongation of fatty acids protein. (310 aa)
	NEQG_01001	Uncharacterized protein. (305 aa)
	NEQG_00859	J domain-containing protein. (155 aa)
	NEQG_01966	Uncharacterized protein. (177 aa)
	NEQG_02020	Uncharacterized protein. (261 aa)
	NEQG_02023	Serine palmitoyltransferase. (475 aa)
	ALG13	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. (157 aa)
	NEQG_01516	Uncharacterized protein. (458 aa)
	NEQG_01563	SRP54 domain-containing protein. (441 aa)
	NEQG_01701	Uncharacterized protein. (688 aa)
	NEQG_01782	Uncharacterized protein. (362 aa)
	NEQG_01055	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (196 aa)
	NEQG_01073	Uncharacterized protein. (445 aa)
	NEQG_01346	Uncharacterized protein. (279 aa)
	NEQG_01433	RING-type domain-containing protein. (309 aa)
	NEQG_00853	Uncharacterized protein. (227 aa)
	NEQG_02547	FCP1 homology domain-containing protein. (235 aa)
	NEQG_02571	Uncharacterized protein. (208 aa)
	NEQG_02419	Uncharacterized protein. (161 aa)
	NEQG_02199	Preprotein translocase; Belongs to the SecY/SEC61-alpha family. (468 aa)
	NEQG_01874	Uncharacterized protein. (1032 aa)

Your Current Organism:

Nematocida parisii

NCBI taxonomy Id: 935791
Other names: N. parisii ERTm3, Nematocida parisii ERTm3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG13	NEQG_00242	I3EFI0	I3EJS5	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Uncharacterized protein.	0.783
ALG13	NEQG_00274	I3EFI0	I3EJV7	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	IRE protein kinase.	0.766
ALG13	NEQG_01073	I3EFI0	I3EGN6	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Uncharacterized protein.	0.949
ALG13	NEQG_01701	I3EFI0	I3EGB0	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	Uncharacterized protein.	0.478
NEQG_00016	NEQG_00274	I3EJ49	I3EJV7	RING-type domain-containing protein.	IRE protein kinase.	0.561
NEQG_00016	NEQG_00398	I3EJ49	I3EK81	RING-type domain-containing protein.	Transitional endoplasmic reticulum ATPase TER94.	0.939
NEQG_00016	NEQG_00499	I3EJ49	I3EKI2	RING-type domain-containing protein.	Ubiquitin-conjugating enzyme E2 g; Belongs to the ubiquitin-conjugating enzyme family.	0.861
NEQG_00016	NEQG_00546	I3EJ49	I3EKM9	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.995
NEQG_00016	NEQG_00853	I3EJ49	I3EII7	RING-type domain-containing protein.	Uncharacterized protein.	0.660
NEQG_00016	NEQG_01516	I3EJ49	I3EFS5	RING-type domain-containing protein.	Uncharacterized protein.	0.993
NEQG_00016	NEQG_02199	I3EJ49	I3EEK5	RING-type domain-containing protein.	Preprotein translocase; Belongs to the SecY/SEC61-alpha family.	0.665
NEQG_00054	NEQG_01563	I3EJ87	I3EFX2	Signal peptidase complex catalytic subunit SEC11.	SRP54 domain-containing protein.	0.652
NEQG_00054	NEQG_01701	I3EJ87	I3EGB0	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.458
NEQG_00054	NEQG_01966	I3EJ87	I3EF97	Signal peptidase complex catalytic subunit SEC11.	Uncharacterized protein.	0.925
NEQG_00054	NEQG_02199	I3EJ87	I3EEK5	Signal peptidase complex catalytic subunit SEC11.	Preprotein translocase; Belongs to the SecY/SEC61-alpha family.	0.602
NEQG_00140	NEQG_00242	I3EJH3	I3EJS5	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.512
NEQG_00242	ALG13	I3EJS5	I3EFI0	Uncharacterized protein.	UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.	0.783
NEQG_00242	NEQG_00140	I3EJS5	I3EJH3	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.512
NEQG_00242	NEQG_00274	I3EJS5	I3EJV7	Uncharacterized protein.	IRE protein kinase.	0.603
NEQG_00242	NEQG_00728	I3EJS5	I3EI62	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.586