(20 nodes) MAPK signaling pathway - yeast network (Nematocida parisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEQG_00541	Transcription factor steA. (322 aa)
	NEQG_00360	Uncharacterized protein. (397 aa)
	NEQG_00024	Atypical/PIKK protein kinase; Belongs to the PI3/PI4-kinase family. (1468 aa)
	NEQG_00553	Uncharacterized protein. (217 aa)
	NEQG_02565	AGC/PKC protein kinase. (350 aa)
	NEQG_02113	MADS-box domain-containing protein. (348 aa)
	NEQG_01836	Rhodanese domain-containing protein. (315 aa)
	NEQG_01860	FH2 domain-containing protein. (1085 aa)
	NEQG_01891	TPR_REGION domain-containing protein. (553 aa)
	NEQG_02021	Glycerol-3-phosphate dehydrogenase. (196 aa)
	NEQG_02065	Rho GTPase. (196 aa)
	NEQG_01650	Uncharacterized protein. (678 aa)
	NEQG_01780	Uncharacterized protein. (190 aa)
	NEQG_01129	Uncharacterized protein. (141 aa)
	NEQG_01352	Uncharacterized protein. (171 aa)
	NEQG_00702	Cell division cycle protein Cdc13; Belongs to the cyclin family. (292 aa)
	NEQG_00757	CYCLIN domain-containing protein; Belongs to the cyclin family. (395 aa)
	NEQG_00786	14-3-3 family protein beta/alpha; Belongs to the 14-3-3 family. (251 aa)
	NEQG_00948	Uncharacterized protein. (184 aa)
	NEQG_01029	WEE protein kinase. (877 aa)

Your Current Organism:

Nematocida parisii

NCBI taxonomy Id: 935791
Other names: N. parisii ERTm3, Nematocida parisii ERTm3

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEQG_00360	NEQG_00541	I3EK43	I3EKM4	Uncharacterized protein.	Transcription factor steA.	0.662
NEQG_00360	NEQG_00553	I3EK43	I3EKN6	Uncharacterized protein.	Uncharacterized protein.	0.662
NEQG_00360	NEQG_00948	I3EK43	I3EIT2	Uncharacterized protein.	Uncharacterized protein.	0.662
NEQG_00360	NEQG_01129	I3EK43	I3EGU2	Uncharacterized protein.	Uncharacterized protein.	0.662
NEQG_00360	NEQG_01352	I3EK43	I3EHG5	Uncharacterized protein.	Uncharacterized protein.	0.662
NEQG_00541	NEQG_00360	I3EKM4	I3EK43	Transcription factor steA.	Uncharacterized protein.	0.662
NEQG_00541	NEQG_00702	I3EKM4	I3EI36	Transcription factor steA.	Cell division cycle protein Cdc13; Belongs to the cyclin family.	0.736
NEQG_00541	NEQG_00757	I3EKM4	I3EI91	Transcription factor steA.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.549
NEQG_00541	NEQG_00786	I3EKM4	I3EIC0	Transcription factor steA.	14-3-3 family protein beta/alpha; Belongs to the 14-3-3 family.	0.495
NEQG_00541	NEQG_01860	I3EKM4	I3EEZ1	Transcription factor steA.	FH2 domain-containing protein.	0.553
NEQG_00541	NEQG_01891	I3EKM4	I3EF22	Transcription factor steA.	TPR_REGION domain-containing protein.	0.454
NEQG_00541	NEQG_02113	I3EKM4	I3EEB9	Transcription factor steA.	MADS-box domain-containing protein.	0.735
NEQG_00553	NEQG_00360	I3EKN6	I3EK43	Uncharacterized protein.	Uncharacterized protein.	0.662
NEQG_00553	NEQG_00702	I3EKN6	I3EI36	Uncharacterized protein.	Cell division cycle protein Cdc13; Belongs to the cyclin family.	0.736
NEQG_00553	NEQG_00757	I3EKN6	I3EI91	Uncharacterized protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.549
NEQG_00553	NEQG_00786	I3EKN6	I3EIC0	Uncharacterized protein.	14-3-3 family protein beta/alpha; Belongs to the 14-3-3 family.	0.495
NEQG_00553	NEQG_01860	I3EKN6	I3EEZ1	Uncharacterized protein.	FH2 domain-containing protein.	0.553
NEQG_00553	NEQG_01891	I3EKN6	I3EF22	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.454
NEQG_00553	NEQG_02113	I3EKN6	I3EEB9	Uncharacterized protein.	MADS-box domain-containing protein.	0.735
NEQG_00702	NEQG_00541	I3EI36	I3EKM4	Cell division cycle protein Cdc13; Belongs to the cyclin family.	Transcription factor steA.	0.736