node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBY82832.1 | kdtA | HFELIS_07480 | HFELIS_09580 | Putative metallophosphoesterase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.420 |
CBY82832.1 | lpxB | HFELIS_07480 | HFELIS_05050 | Putative metallophosphoesterase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.948 |
CBY82832.1 | lpxD | HFELIS_07480 | HFELIS_14050 | Putative metallophosphoesterase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.934 |
CBY82832.1 | lpxK | HFELIS_07480 | HFELIS_09920 | Putative metallophosphoesterase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.506 |
fabZ | lpxA | HFELIS_06990 | HFELIS_07000 | Hydroxymyristoyl-(acyl-carrier protein)dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucos amine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.990 |
fabZ | lpxB | HFELIS_06990 | HFELIS_05050 | Hydroxymyristoyl-(acyl-carrier protein)dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.585 |
fabZ | lpxC | HFELIS_06990 | HFELIS_04340 | Hydroxymyristoyl-(acyl-carrier protein)dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | UDP-3-O-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.940 |
fabZ | lpxD | HFELIS_06990 | HFELIS_14050 | Hydroxymyristoyl-(acyl-carrier protein)dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.849 |
fabZ | lpxK | HFELIS_06990 | HFELIS_09920 | Hydroxymyristoyl-(acyl-carrier protein)dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.428 |
kdsA | kdsB | HFELIS_07560 | HFELIS_01200 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | 0.864 |
kdsA | kdsC | HFELIS_07560 | HFELIS_12680 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. | 0.990 |
kdsA | kdtA | HFELIS_07560 | HFELIS_09580 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.829 |
kdsA | kpsF | HFELIS_07560 | HFELIS_11430 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.991 |
kdsA | lpxA | HFELIS_07560 | HFELIS_07000 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucos amine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.638 |
kdsA | lpxB | HFELIS_07560 | HFELIS_05050 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.729 |
kdsA | lpxC | HFELIS_07560 | HFELIS_04340 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.696 |
kdsA | lpxD | HFELIS_07560 | HFELIS_14050 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.630 |
kdsA | lpxK | HFELIS_07560 | HFELIS_09920 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.801 |
kdsB | kdsA | HFELIS_01200 | HFELIS_07560 | 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.864 |
kdsB | kdsC | HFELIS_01200 | HFELIS_12680 | 3-deoxy-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. | 0.959 |