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CVT25_005829 CVT25_005829 CVT25_006040 CVT25_006040 CVT25_012089 CVT25_012089 CVT25_012683 CVT25_012683 CVT25_012696 CVT25_012696 CVT25_014504 CVT25_014504 CVT25_005450 CVT25_005450 CVT25_009165 CVT25_009165 CVT25_004389 CVT25_004389 CVT25_004239 CVT25_004239 CVT25_010895 CVT25_010895 CVT25_010928 CVT25_010928 CVT25_011310 CVT25_011310 CVT25_011378 CVT25_011378 CVT25_011317 CVT25_011317 CVT25_011087 CVT25_011087 CVT25_011232 CVT25_011232 CVT25_011134 CVT25_011134 CVT25_011159 CVT25_011159 CVT25_015370 CVT25_015370 CVT25_015631 CVT25_015631 CVT25_011862 CVT25_011862 CVT25_010552 CVT25_010552 CVT25_010585 CVT25_010585 CVT25_010724 CVT25_010724 CVT25_002817 CVT25_002817 CVT25_002678 CVT25_002678 CVT25_002624 CVT25_002624 CVT25_003263 CVT25_003263 CVT25_003286 CVT25_003286 CVT25_003502 CVT25_003502 CVT25_013420 CVT25_013420 CVT25_013785 CVT25_013785 CVT25_007155 CVT25_007155 CVT25_009191 CVT25_009191 CVT25_009200 CVT25_009200 CVT25_009674 CVT25_009674 CVT25_003979 CVT25_003979 CVT25_007036 CVT25_007036 CVT25_006302 CVT25_006302 CVT25_006307 CVT25_006307 CVT25_000905 CVT25_000905 CVT25_000901 CVT25_000901 CVT25_002024 CVT25_002024 CVT25_002020 CVT25_002020 CVT25_003332 CVT25_003332 CVT25_013217 CVT25_013217 CVT25_006675 CVT25_006675 CVT25_006573 CVT25_006573 CVT25_006571 CVT25_006571 CVT25_006159 CVT25_006159 CVT25_008105 CVT25_008105 CVT25_008222 CVT25_008222 CVT25_001084 CVT25_001084 CVT25_005174 CVT25_005174 CVT25_012443 CVT25_012443 CVT25_009937 CVT25_009937 CVT25_010222 CVT25_010222 CVT25_003157 CVT25_003157 CVT25_003158 CVT25_003158 CVT25_002206 CVT25_002206 CVT25_002209 CVT25_002209 CVT25_012819 CVT25_012819 CVT25_012168 CVT25_012168 CVT25_002195 CVT25_002195 CVT25_012329 CVT25_012329 CVT25_013856 CVT25_013856 CVT25_012254 CVT25_012254 CVT25_014915 CVT25_014915 CVT25_014982 CVT25_014982 CVT25_015858 CVT25_015858 CVT25_004713 CVT25_004713 CVT25_013950 CVT25_013950 CVT25_008954 CVT25_008954 CVT25_010422 CVT25_010422 CVT25_014015 CVT25_014015 CVT25_015358 CVT25_015358 CVT25_004317 CVT25_004317 CVT25_003112 CVT25_003112 CVT25_015217 CVT25_015217 CVT25_012732 CVT25_012732 CVT25_012713 CVT25_012713 CVT25_009844 CVT25_009844 CVT25_009885 CVT25_009885 CVT25_009895 CVT25_009895 CVT25_009379 CVT25_009379
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CVT25_005829Zn(2)-C6 fungal-type domain-containing protein. (370 aa)
CVT25_006040Citrate synthase; Belongs to the citrate synthase family. (492 aa)
CVT25_012089Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
CVT25_012683Lipoyl-binding domain-containing protein. (255 aa)
CVT25_012696Uncharacterized protein. (279 aa)
CVT25_014504Uncharacterized protein. (346 aa)
CVT25_005450Uncharacterized protein; Belongs to the TPP enzyme family. (674 aa)
CVT25_009165FAD-binding PCMH-type domain-containing protein. (479 aa)
CVT25_004389Uncharacterized protein. (507 aa)
CVT25_004239Uncharacterized protein. (1460 aa)
CVT25_0108953-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (757 aa)
CVT25_010928Peptidase_M24 domain-containing protein. (452 aa)
CVT25_011310FAD-binding PCMH-type domain-containing protein. (574 aa)
CVT25_011378Uncharacterized protein. (441 aa)
CVT25_011317Transket_pyr domain-containing protein. (418 aa)
CVT25_0110873-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (382 aa)
CVT25_011232DUF1752 domain-containing protein. (267 aa)
CVT25_011134Uncharacterized protein. (131 aa)
CVT25_011159Iso_dh domain-containing protein. (361 aa)
CVT25_015370Malate dehydrogenase. (374 aa)
CVT25_015631Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (1411 aa)
CVT25_011862Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (270 aa)
CVT25_010552Transket_pyr domain-containing protein. (933 aa)
CVT25_010585Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (158 aa)
CVT25_010724Uncharacterized protein. (402 aa)
CVT25_002817NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1052 aa)
CVT25_002678Uncharacterized protein. (487 aa)
CVT25_002624FAD-binding PCMH-type domain-containing protein. (496 aa)
CVT25_003263FAD-binding PCMH-type domain-containing protein. (495 aa)
CVT25_003286Lipoyl-binding domain-containing protein. (439 aa)
CVT25_003502Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (776 aa)
CVT25_013420Uncharacterized protein. (154 aa)
CVT25_013785Malic enzyme. (564 aa)
CVT25_007155FMN hydroxy acid dehydrogenase domain-containing protein. (460 aa)
CVT25_009191Iso_dh domain-containing protein. (380 aa)
CVT25_009200Malate dehydrogenase. (337 aa)
CVT25_009674Uncharacterized protein; Belongs to the ketol-acid reductoisomerase family. (349 aa)
CVT25_003979Aspartate aminotransferase. (465 aa)
CVT25_007036Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (484 aa)
CVT25_006302Uncharacterized protein; Belongs to the cytochrome b5 family. (486 aa)
CVT25_006307Uncharacterized protein; Belongs to the cytochrome b5 family. (498 aa)
CVT25_000905Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
CVT25_000901Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (517 aa)
CVT25_002024Isochorismatase domain-containing protein. (220 aa)
CVT25_002020Uncharacterized protein. (179 aa)
CVT25_003332MR_MLE domain-containing protein. (380 aa)
CVT25_013217FMN hydroxy acid dehydrogenase domain-containing protein. (518 aa)
CVT25_006675Uncharacterized protein. (89 aa)
CVT25_006573FAD-binding PCMH-type domain-containing protein. (583 aa)
CVT25_006571FAD-binding PCMH-type domain-containing protein. (596 aa)
CVT25_006159Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (167 aa)
CVT25_008105Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (401 aa)
CVT25_008222Uncharacterized protein. (574 aa)
CVT25_001084Citrate synthase; Belongs to the citrate synthase family. (460 aa)
CVT25_005174FAD-binding PCMH-type domain-containing protein. (475 aa)
CVT25_012443FAD-binding PCMH-type domain-containing protein. (493 aa)
CVT25_009937Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
CVT25_010222Aspartate aminotransferase. (442 aa)
CVT25_003157Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (1085 aa)
CVT25_003158Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (407 aa)
CVT25_002206Uncharacterized protein. (501 aa)
CVT25_002209Uncharacterized protein; Belongs to the cytochrome b5 family. (486 aa)
CVT25_012819Acetolactate synthase. (683 aa)
CVT25_012168ACT domain-containing protein. (1198 aa)
CVT25_002195Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (448 aa)
CVT25_012329FAD-binding PCMH-type domain-containing protein. (1015 aa)
CVT25_013856Uncharacterized protein. (550 aa)
CVT25_012254Uncharacterized protein. (1161 aa)
CVT25_014915Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (416 aa)
CVT25_014982Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
CVT25_015858Uncharacterized protein. (317 aa)
CVT25_004713GFA domain-containing protein. (186 aa)
CVT25_013950Citrate synthase; Belongs to the citrate synthase family. (468 aa)
CVT25_008954Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (460 aa)
CVT25_010422Malic enzyme. (637 aa)
CVT25_014015Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (585 aa)
CVT25_015358Dihydrolipoyl dehydrogenase. (504 aa)
CVT25_0043172-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (441 aa)
CVT25_003112Transket_pyr domain-containing protein. (1010 aa)
CVT25_015217Pyruvate carboxyltransferase domain-containing protein. (791 aa)
CVT25_012732Cytochrome b5 heme-binding domain-containing protein. (581 aa)
CVT25_012713Uncharacterized protein. (536 aa)
CVT25_009844Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (372 aa)
CVT25_009885Iso_dh domain-containing protein. (373 aa)
CVT25_009895Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (378 aa)
CVT25_009379Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1198 aa)
Your Current Organism:
Psilocybe cyanescens
NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481
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