(11 nodes) Mixed, incl. ICL/PEPM domain, and D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain network (Psilocybe cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT25_014857	Isocitrate lyase. (552 aa)
	CVT25_012767	Uncharacterized protein. (439 aa)
	CVT25_008175	Uncharacterized protein. (306 aa)
	CVT25_011579	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
	CVT25_013848	Isocitrate lyase. (538 aa)
	CVT25_014138	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (379 aa)
	CVT25_013944	Uncharacterized protein; Belongs to the DapA family. (312 aa)
	CVT25_000165	Malate synthase; Belongs to the malate synthase family. (542 aa)
	CVT25_015276	Uncharacterized protein; Belongs to the DapA family. (345 aa)
	CVT25_005555	Uncharacterized protein. (1674 aa)
	CVT25_013560	Uncharacterized protein. (356 aa)

Your Current Organism:

Psilocybe cyanescens

NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT25_000165	CVT25_005555	A0A409XQG9	A0A409XRX4	Malate synthase; Belongs to the malate synthase family.	Uncharacterized protein.	0.891
CVT25_000165	CVT25_011579	A0A409XQG9	A0A409XCE7	Malate synthase; Belongs to the malate synthase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.931
CVT25_000165	CVT25_012767	A0A409XQG9	A0A409X4F3	Malate synthase; Belongs to the malate synthase family.	Uncharacterized protein.	0.862
CVT25_000165	CVT25_013560	A0A409XQG9	A0A409XSQ4	Malate synthase; Belongs to the malate synthase family.	Uncharacterized protein.	0.798
CVT25_000165	CVT25_013848	A0A409XQG9	A0A409XFZ2	Malate synthase; Belongs to the malate synthase family.	Isocitrate lyase.	0.999
CVT25_000165	CVT25_013944	A0A409XQG9	A0A409XJT7	Malate synthase; Belongs to the malate synthase family.	Uncharacterized protein; Belongs to the DapA family.	0.871
CVT25_000165	CVT25_014138	A0A409XQG9	A0A409XGE1	Malate synthase; Belongs to the malate synthase family.	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.897
CVT25_000165	CVT25_014857	A0A409XQG9	A0A409WF00	Malate synthase; Belongs to the malate synthase family.	Isocitrate lyase.	0.997
CVT25_000165	CVT25_015276	A0A409XQG9	A0A409XRD0	Malate synthase; Belongs to the malate synthase family.	Uncharacterized protein; Belongs to the DapA family.	0.850
CVT25_005555	CVT25_000165	A0A409XRX4	A0A409XQG9	Uncharacterized protein.	Malate synthase; Belongs to the malate synthase family.	0.891
CVT25_005555	CVT25_008175	A0A409XRX4	A0A409X9I1	Uncharacterized protein.	Uncharacterized protein.	0.883
CVT25_005555	CVT25_011579	A0A409XRX4	A0A409XCE7	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.877
CVT25_005555	CVT25_012767	A0A409XRX4	A0A409X4F3	Uncharacterized protein.	Uncharacterized protein.	0.523
CVT25_005555	CVT25_013560	A0A409XRX4	A0A409XSQ4	Uncharacterized protein.	Uncharacterized protein.	0.403
CVT25_005555	CVT25_013848	A0A409XRX4	A0A409XFZ2	Uncharacterized protein.	Isocitrate lyase.	0.883
CVT25_005555	CVT25_013944	A0A409XRX4	A0A409XJT7	Uncharacterized protein.	Uncharacterized protein; Belongs to the DapA family.	0.796
CVT25_005555	CVT25_014857	A0A409XRX4	A0A409WF00	Uncharacterized protein.	Isocitrate lyase.	0.865
CVT25_005555	CVT25_015276	A0A409XRX4	A0A409XRD0	Uncharacterized protein.	Uncharacterized protein; Belongs to the DapA family.	0.850
CVT25_008175	CVT25_005555	A0A409X9I1	A0A409XRX4	Uncharacterized protein.	Uncharacterized protein.	0.883
CVT25_008175	CVT25_011579	A0A409X9I1	A0A409XCE7	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.925