(56 nodes) RNA 3-end processing network (Psilocybe cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT25_015783	Bms1-type G domain-containing protein. (791 aa)
	CVT25_011667	Uncharacterized protein; Belongs to the RNR ribonuclease family. (1006 aa)
	CVT25_007463	Uncharacterized protein. (310 aa)
	CVT25_002512	Uncharacterized protein. (334 aa)
	CLP1	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation. (485 aa)
	CVT25_000184	Exonuclease domain-containing protein. (649 aa)
	CVT25_004316	Uncharacterized protein. (233 aa)
	CVT25_007303	Uncharacterized protein. (103 aa)
	CVT25_010368	Uncharacterized protein. (340 aa)
	CVT25_008705	Uncharacterized protein. (2086 aa)
	CVT25_000754	Uncharacterized protein. (612 aa)
	CVT25_000432	CDC73_C domain-containing protein. (418 aa)
	CVT25_013746	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
	CVT25_004118	Uncharacterized protein. (324 aa)
	CVT25_006219	Uncharacterized protein. (417 aa)
	CVT25_013941	RNase_PH domain-containing protein. (262 aa)
	CVT25_010136	Uncharacterized protein. (516 aa)
	CVT25_015852	Uncharacterized protein. (765 aa)
	CVT25_013117	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (104 aa)
	CVT25_013086	RNase_PH domain-containing protein. (339 aa)
	CVT25_006290	Lactamase_B_4 domain-containing protein. (929 aa)
	CVT25_012816	Uncharacterized protein. (758 aa)
	CVT25_012202	Uncharacterized protein. (405 aa)
	CVT25_012824	NTP_transf_2 domain-containing protein. (284 aa)
	CVT25_012818	Uncharacterized protein. (1281 aa)
	CVT25_002197	PUA domain-containing protein. (514 aa)
	CVT25_006487	Exonuclease domain-containing protein. (364 aa)
	CVT25_006447	Lactamase_B domain-containing protein. (478 aa)
	CVT25_009132	Suf domain-containing protein. (861 aa)
	CVT25_009113	Uncharacterized protein. (468 aa)
	CVT25_010223	Uncharacterized protein. (293 aa)
	CVT25_004889	Uncharacterized protein. (807 aa)
	CVT25_002840	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (216 aa)
	CVT25_006120	RNase_PH domain-containing protein. (266 aa)
	CVT25_007013	WD_REPEATS_REGION domain-containing protein. (400 aa)
	CVT25_008322	WD_REPEATS_REGION domain-containing protein. (591 aa)
	USB1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (314 aa)
	CVT25_002808	Uncharacterized protein. (78 aa)
	CVT25_011624	RPOL4c domain-containing protein. (137 aa)
	CVT25_015599	Uncharacterized protein. (300 aa)
	CVT25_015562	CPSF_A domain-containing protein. (1441 aa)
	CVT25_015377	Uncharacterized protein. (893 aa)
	CVT25_015323	Uncharacterized protein. (282 aa)
	CVT25_011175	Uncharacterized protein. (665 aa)
	CVT25_011089	CID domain-containing protein. (657 aa)
	CVT25_010951	Lactamase_B domain-containing protein. (388 aa)
	CVT25_014855	Uncharacterized protein. (330 aa)
	CVT25_012921	Plus3 domain-containing protein. (2332 aa)
	CVT25_004829	Fip1 domain-containing protein. (502 aa)
	CVT25_012840	HRDC domain-containing protein. (891 aa)
	CVT25_005526	Uncharacterized protein. (589 aa)
	CVT25_005425	Uncharacterized protein. (1195 aa)
	CVT25_010290	CID domain-containing protein. (622 aa)
	CVT25_012087	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (600 aa)
	CVT25_012071	Uncharacterized protein. (323 aa)
	CVT25_005956	PolyA_pol domain-containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (561 aa)

Your Current Organism:

Psilocybe cyanescens

NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLP1	CVT25_002840	A0A409XRF6	A0A409X4R6	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.862
CLP1	CVT25_004829	A0A409XRF6	A0A409VT63	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Fip1 domain-containing protein.	0.965
CLP1	CVT25_005425	A0A409XRF6	A0A409VQN1	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Uncharacterized protein.	0.872
CLP1	CVT25_008322	A0A409XRF6	A0A409WV80	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	WD_REPEATS_REGION domain-containing protein.	0.805
CLP1	CVT25_009132	A0A409XRF6	A0A409XE24	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Suf domain-containing protein.	0.970
CLP1	CVT25_010223	A0A409XRF6	A0A409XD99	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Uncharacterized protein.	0.962
CLP1	CVT25_010368	A0A409XRF6	A0A409XP07	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Uncharacterized protein.	0.990
CLP1	CVT25_011089	A0A409XRF6	A0A409WGJ4	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	CID domain-containing protein.	0.998
CLP1	CVT25_012087	A0A409XRF6	A0A409VMW8	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.822
CLP1	CVT25_015562	A0A409XRF6	A0A409WHK1	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	CPSF_A domain-containing protein.	0.923
CLP1	CVT25_015852	A0A409XRF6	A0A409XIG5	mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.	Uncharacterized protein.	0.944
CVT25_000184	CVT25_002808	A0A409XQ90	A0A409WL99	Exonuclease domain-containing protein.	Uncharacterized protein.	0.421
CVT25_000184	CVT25_005526	A0A409XQ90	A0A409VQY9	Exonuclease domain-containing protein.	Uncharacterized protein.	0.502
CVT25_000184	CVT25_005956	A0A409XQ90	A0A409VMB6	Exonuclease domain-containing protein.	PolyA_pol domain-containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	0.421
CVT25_000184	CVT25_006120	A0A409XQ90	A0A409WZ02	Exonuclease domain-containing protein.	RNase_PH domain-containing protein.	0.491
CVT25_000184	CVT25_008322	A0A409XQ90	A0A409WV80	Exonuclease domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.486
CVT25_000184	CVT25_010136	A0A409XQ90	A0A409XJ05	Exonuclease domain-containing protein.	Uncharacterized protein.	0.444
CVT25_000184	CVT25_011667	A0A409XQ90	A0A409XWI1	Exonuclease domain-containing protein.	Uncharacterized protein; Belongs to the RNR ribonuclease family.	0.592
CVT25_000184	CVT25_013941	A0A409XQ90	A0A409XJW9	Exonuclease domain-containing protein.	RNase_PH domain-containing protein.	0.491
CVT25_000184	CVT25_014855	A0A409XQ90	A0A409WER3	Exonuclease domain-containing protein.	Uncharacterized protein.	0.689