(44 nodes) Dicarboxylic acid metabolic process network (Psilocybe cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT25_001240	Uncharacterized protein. (189 aa)
	CVT25_001245	Uncharacterized protein. (531 aa)
	CVT25_012592	FAD_binding_3 domain-containing protein. (265 aa)
	CVT25_003538	Pterin-binding domain-containing protein. (685 aa)
	CVT25_000553	Uncharacterized protein. (498 aa)
	CVT25_003979	Aspartate aminotransferase. (465 aa)
	CVT25_009200	Malate dehydrogenase. (337 aa)
	CVT25_014645	Mur_ligase_M domain-containing protein. (494 aa)
	CVT25_013785	Malic enzyme. (564 aa)
	CVT25_001970	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (205 aa)
	CVT25_001539	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. Belongs to the EPSP synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1885 aa)
	CVT25_002683	Uncharacterized protein. (266 aa)
	CVT25_002817	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1052 aa)
	CVT25_002896	Uncharacterized protein. (137 aa)
	CVT25_011809	Glutamine amidotransferase type-2 domain-containing protein. (2145 aa)
	CVT25_015370	Malate dehydrogenase. (374 aa)
	CVT25_011014	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (295 aa)
	CVT25_000078	FAD_binding_3 domain-containing protein. (185 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (442 aa)
	CVT25_006552	Uncharacterized protein. (505 aa)
	CVT25_004387	Chorismate mutase. (302 aa)
	CVT25_005758	Glutamine amidotransferase type-1 domain-containing protein. (752 aa)
	CVT25_005311	Uncharacterized protein. (263 aa)
	CVT25_008404	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (757 aa)
	CVT25_007653	Uncharacterized protein. (360 aa)
	CVT25_008137	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (562 aa)
	CVT25_004936	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (484 aa)
	CVT25_005979	Chorismate synthase. (409 aa)
	CVT25_012089	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
	CVT25_007467	Semialdhyde_dh domain-containing protein. (451 aa)
	CVT25_003112	Transket_pyr domain-containing protein. (1010 aa)
	CVT25_003906	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (547 aa)
	CVT25_010510	Uncharacterized protein. (212 aa)
	CVT25_010422	Malic enzyme. (637 aa)
	CVT25_008721	GTP_cyclohydroI domain-containing protein. (299 aa)
	CVT25_012665	Semialdhyde_dh domain-containing protein. (318 aa)
	CVT25_006291	WAPL domain-containing protein. (868 aa)
	CVT25_013856	Uncharacterized protein. (550 aa)
	CVT25_002206	Uncharacterized protein. (501 aa)
	CVT25_006465	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (536 aa)
	CVT25_010222	Aspartate aminotransferase. (442 aa)
	CVT25_009906	ADSL_C domain-containing protein. (454 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (174 aa)
	CVT25_005173	Uncharacterized protein. (427 aa)

Your Current Organism:

Psilocybe cyanescens

NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA1	BNA5	A0A409XBQ8	A0A409VWW9	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.976
BNA1	CVT25_000078	A0A409XBQ8	A0A409VWY5	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	FAD_binding_3 domain-containing protein.	0.759
BNA1	CVT25_006465	A0A409XBQ8	A0A409XE79	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.438
BNA1	CVT25_008137	A0A409XBQ8	A0A409XSS4	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.438
BNA1	CVT25_011014	A0A409XBQ8	A0A409WG01	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.596
BNA1	CVT25_012592	A0A409XBQ8	A0A409X7V8	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	FAD_binding_3 domain-containing protein.	0.760
BNA5	BNA1	A0A409VWW9	A0A409XBQ8	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.976
BNA5	CVT25_000078	A0A409VWW9	A0A409VWY5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	FAD_binding_3 domain-containing protein.	0.941
BNA5	CVT25_011014	A0A409VWW9	A0A409WG01	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.588
BNA5	CVT25_012592	A0A409VWW9	A0A409X7V8	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	FAD_binding_3 domain-containing protein.	0.940
CVT25_000078	BNA1	A0A409VWY5	A0A409XBQ8	FAD_binding_3 domain-containing protein.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.759
CVT25_000078	BNA5	A0A409VWY5	A0A409VWW9	FAD_binding_3 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.941
CVT25_000078	CVT25_012592	A0A409VWY5	A0A409X7V8	FAD_binding_3 domain-containing protein.	FAD_binding_3 domain-containing protein.	0.951
CVT25_000553	CVT25_002206	A0A409WZT3	A0A409XF21	Uncharacterized protein.	Uncharacterized protein.	0.534
CVT25_000553	CVT25_003906	A0A409WZT3	A0A409XPR6	Uncharacterized protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.437
CVT25_000553	CVT25_006291	A0A409WZT3	A0A409XH45	Uncharacterized protein.	WAPL domain-containing protein.	0.559
CVT25_000553	CVT25_009200	A0A409WZT3	A0A409WWD0	Uncharacterized protein.	Malate dehydrogenase.	0.618
CVT25_000553	CVT25_010422	A0A409WZT3	A0A409XP26	Uncharacterized protein.	Malic enzyme.	0.531
CVT25_000553	CVT25_012089	A0A409WZT3	A0A409VMU3	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.445
CVT25_000553	CVT25_013785	A0A409WZT3	A0A409WTY3	Uncharacterized protein.	Malic enzyme.	0.460