(26 nodes) RNA phosphodiester bond hydrolysis, exonucleolytic network (Psilocybe cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT25_000184	Exonuclease domain-containing protein. (649 aa)
	CVT25_009889	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1447 aa)
	CVT25_002512	Uncharacterized protein. (334 aa)
	CVT25_007463	Uncharacterized protein. (310 aa)
	CVT25_011667	Uncharacterized protein; Belongs to the RNR ribonuclease family. (1006 aa)
	CVT25_014212	Uncharacterized protein. (1078 aa)
	CVT25_006120	RNase_PH domain-containing protein. (266 aa)
	USB1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (314 aa)
	CVT25_015323	Uncharacterized protein. (282 aa)
	CVT25_011231	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1374 aa)
	CVT25_014855	Uncharacterized protein. (330 aa)
	CVT25_014070	Brix domain-containing protein. (840 aa)
	CVT25_013086	RNase_PH domain-containing protein. (339 aa)
	CVT25_004889	Uncharacterized protein. (807 aa)
	CVT25_012573	USP domain-containing protein. (1097 aa)
	CVT25_005624	Uncharacterized protein. (351 aa)
	CVT25_014924	3'-5' exonuclease domain-containing protein. (448 aa)
	CVT25_006613	Uncharacterized protein. (773 aa)
	CVT25_013941	RNase_PH domain-containing protein. (262 aa)
	CVT25_008914	RNB domain-containing protein. (942 aa)
	CVT25_008746	XRN_N domain-containing protein. (159 aa)
	CVT25_004316	Uncharacterized protein. (233 aa)
	CVT25_010204	Endo/exonuclease/phosphatase domain-containing protein. (454 aa)
	CVT25_011589	Bulb-type lectin domain-containing protein. (259 aa)
	CVT25_012840	HRDC domain-containing protein. (891 aa)
	CVT25_006487	Exonuclease domain-containing protein. (364 aa)

Your Current Organism:

Psilocybe cyanescens

NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT25_000184	CVT25_006120	A0A409XQ90	A0A409WZ02	Exonuclease domain-containing protein.	RNase_PH domain-containing protein.	0.491
CVT25_000184	CVT25_006613	A0A409XQ90	A0A409XIQ4	Exonuclease domain-containing protein.	Uncharacterized protein.	0.492
CVT25_000184	CVT25_008914	A0A409XQ90	A0A409XN73	Exonuclease domain-containing protein.	RNB domain-containing protein.	0.535
CVT25_000184	CVT25_009889	A0A409XQ90	A0A409XTL9	Exonuclease domain-containing protein.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.	0.541
CVT25_000184	CVT25_011589	A0A409XQ90	A0A409XCF9	Exonuclease domain-containing protein.	Bulb-type lectin domain-containing protein.	0.953
CVT25_000184	CVT25_011667	A0A409XQ90	A0A409XWI1	Exonuclease domain-containing protein.	Uncharacterized protein; Belongs to the RNR ribonuclease family.	0.592
CVT25_000184	CVT25_013941	A0A409XQ90	A0A409XJW9	Exonuclease domain-containing protein.	RNase_PH domain-containing protein.	0.491
CVT25_000184	CVT25_014855	A0A409XQ90	A0A409WER3	Exonuclease domain-containing protein.	Uncharacterized protein.	0.689
CVT25_002512	CVT25_004316	A0A409XUQ1	A0A409XQ08	Uncharacterized protein.	Uncharacterized protein.	0.999
CVT25_002512	CVT25_006120	A0A409XUQ1	A0A409WZ02	Uncharacterized protein.	RNase_PH domain-containing protein.	0.999
CVT25_002512	CVT25_007463	A0A409XUQ1	A0A409XVP3	Uncharacterized protein.	Uncharacterized protein.	0.998
CVT25_002512	CVT25_008914	A0A409XUQ1	A0A409XN73	Uncharacterized protein.	RNB domain-containing protein.	0.958
CVT25_002512	CVT25_009889	A0A409XUQ1	A0A409XTL9	Uncharacterized protein.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.	0.972
CVT25_002512	CVT25_011231	A0A409XUQ1	A0A409WGR1	Uncharacterized protein.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.716
CVT25_002512	CVT25_011667	A0A409XUQ1	A0A409XWI1	Uncharacterized protein.	Uncharacterized protein; Belongs to the RNR ribonuclease family.	0.998
CVT25_002512	CVT25_012840	A0A409XUQ1	A0A409VRC1	Uncharacterized protein.	HRDC domain-containing protein.	0.629
CVT25_002512	CVT25_013086	A0A409XUQ1	A0A409XHQ0	Uncharacterized protein.	RNase_PH domain-containing protein.	0.999
CVT25_002512	CVT25_013941	A0A409XUQ1	A0A409XJW9	Uncharacterized protein.	RNase_PH domain-containing protein.	0.999
CVT25_002512	CVT25_014070	A0A409XUQ1	A0A409VPG1	Uncharacterized protein.	Brix domain-containing protein.	0.488
CVT25_002512	CVT25_014212	A0A409XUQ1	A0A409X1R5	Uncharacterized protein.	Uncharacterized protein.	0.994