(51 nodes) Nicotinate and nicotinamide metabolism network (Psilocybe cyanescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CVT25_006471	Deacetylase sirtuin-type domain-containing protein. (298 aa)
	CVT25_001077	Nudix hydrolase domain-containing protein. (471 aa)
	CVT25_013172	Lipase_GDSL domain-containing protein. (342 aa)
	CVT25_010197	SurE domain-containing protein. (338 aa)
	CVT25_012194	IU_nuc_hydro domain-containing protein. (433 aa)
	CVT25_012163	Uncharacterized protein. (850 aa)
	CVT25_014115	Uncharacterized protein. (220 aa)
	CVT25_008157	Uncharacterized protein. (378 aa)
	CVT25_006620	Deacetylase sirtuin-type domain-containing protein. (319 aa)
	CVT25_010144	CN hydrolase domain-containing protein. (713 aa)
	CVT25_013930	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (409 aa)
	CVT25_008272	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (571 aa)
	CVT25_000176	Lipase_GDSL domain-containing protein. (267 aa)
	CVT25_015282	Uncharacterized protein. (1069 aa)
	CVT25_012734	Uncharacterized protein. (248 aa)
	CVT25_007809	Uncharacterized protein. (155 aa)
	CVT25_003818	Uncharacterized protein. (1103 aa)
	CVT25_002539	Deacetylase sirtuin-type domain-containing protein. (617 aa)
	CVT25_001103	Uncharacterized protein. (357 aa)
	CVT25_009433	Uncharacterized protein. (152 aa)
	CVT25_009432	SurE domain-containing protein. (298 aa)
	CVT25_005771	Deacetylase sirtuin-type domain-containing protein; Belongs to the RNase T2 family. (853 aa)
	CVT25_012089	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
	CVT25_010297	Deacetylase sirtuin-type domain-containing protein. (399 aa)
	CVT25_007924	Uncharacterized protein. (540 aa)
	CVT25_004634	Uncharacterized protein. (538 aa)
	CVT25_003962	Uncharacterized protein. (81 aa)
	CVT25_003959	Uncharacterized protein. (1041 aa)
	CVT25_014840	Isochorismatase domain-containing protein. (246 aa)
	CVT25_010832	Deacetylase sirtuin-type domain-containing protein. (1080 aa)
	CVT25_010991	Uncharacterized protein. (251 aa)
	CVT25_011014	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (295 aa)
	CVT25_011126	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)
	CVT25_015369	Uncharacterized protein. (534 aa)
	CVT25_015420	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (310 aa)
	CVT25_010620	Uncharacterized protein. (367 aa)
	CVT25_002272	Uncharacterized protein. (1212 aa)
	CVT25_003378	IU_nuc_hydro domain-containing protein. (404 aa)
	CVT25_003620	Uncharacterized protein. (512 aa)
	CVT25_001770	MFS domain-containing protein. (646 aa)
	CVT25_001950	Uncharacterized protein. (235 aa)
	CVT25_014486	Uncharacterized protein. (532 aa)
	CVT25_014557	Uncharacterized protein. (514 aa)
	CVT25_007118	Uncharacterized protein. (592 aa)
	CVT25_009275	MFS domain-containing protein. (587 aa)
	CVT25_014060	Uncharacterized protein. (454 aa)
	CVT25_004456	Uncharacterized protein. (572 aa)
	CVT25_010401	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
	CVT25_012567	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (683 aa)
	CVT25_000934	Deacetylase sirtuin-type domain-containing protein. (437 aa)
	CVT25_008206	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (289 aa)

Your Current Organism:

Psilocybe cyanescens

NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT25_000934	CVT25_001077	A0A409X8T1	A0A409XB17	Deacetylase sirtuin-type domain-containing protein.	Nudix hydrolase domain-containing protein.	0.869
CVT25_000934	CVT25_002539	A0A409X8T1	A0A409XUP3	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.909
CVT25_000934	CVT25_003378	A0A409X8T1	A0A409WLU7	Deacetylase sirtuin-type domain-containing protein.	IU_nuc_hydro domain-containing protein.	0.780
CVT25_000934	CVT25_005771	A0A409X8T1	A0A409VLN6	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein; Belongs to the RNase T2 family.	0.825
CVT25_000934	CVT25_006471	A0A409X8T1	A0A409XE77	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.787
CVT25_000934	CVT25_006620	A0A409X8T1	A0A409XIP9	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.787
CVT25_000934	CVT25_007118	A0A409X8T1	A0A409WVQ2	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.801
CVT25_000934	CVT25_008157	A0A409X8T1	A0A409XGA2	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.577
CVT25_000934	CVT25_008206	A0A409X8T1	A0A409X9S2	Deacetylase sirtuin-type domain-containing protein.	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.	0.919
CVT25_000934	CVT25_010144	A0A409X8T1	A0A409XJ06	Deacetylase sirtuin-type domain-containing protein.	CN hydrolase domain-containing protein.	0.924
CVT25_000934	CVT25_010297	A0A409X8T1	A0A409VNQ4	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.924
CVT25_000934	CVT25_010832	A0A409X8T1	A0A409WF10	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.856
CVT25_000934	CVT25_011126	A0A409X8T1	A0A409WGT3	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.786
CVT25_000934	CVT25_012163	A0A409X8T1	A0A409XFH2	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.801
CVT25_000934	CVT25_012194	A0A409X8T1	A0A409XFH0	Deacetylase sirtuin-type domain-containing protein.	IU_nuc_hydro domain-containing protein.	0.673
CVT25_000934	CVT25_013930	A0A409X8T1	A0A409XJR1	Deacetylase sirtuin-type domain-containing protein.	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.	0.587
CVT25_000934	CVT25_014840	A0A409X8T1	A0A409WES8	Deacetylase sirtuin-type domain-containing protein.	Isochorismatase domain-containing protein.	0.812
CVT25_000934	CVT25_015420	A0A409X8T1	A0A409WHI0	Deacetylase sirtuin-type domain-containing protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.909
CVT25_001077	CVT25_000934	A0A409XB17	A0A409X8T1	Nudix hydrolase domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.869
CVT25_001077	CVT25_002272	A0A409XB17	A0A409WKE5	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.702