(10 nodes) ATP-grasp fold network (Serpula lacrymans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	F8Q8W1_SERL3	Uncharacterized protein. (2233 aa)
	F8QHM8_SERL3	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1198 aa)
	F8QFA3_SERL3	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (923 aa)
	F8Q2N8_SERL3	Uncharacterized protein. (2258 aa)
	F8Q296_SERL3	Uncharacterized protein. (1261 aa)
	F8PS33_SERL3	Uncharacterized protein. (1148 aa)
	F8PLE2_SERL3	ATP-grasp domain-containing protein. (787 aa)
	F8PG33_SERL3	Uncharacterized protein. (738 aa)
	F8PFG2_SERL3	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (417 aa)
	F8PFA4_SERL3	ATP-grasp domain-containing protein. (320 aa)

Your Current Organism:

Serpula lacrymans

NCBI taxonomy Id: 936435
Other names: S. lacrymans var. lacrymans S7.3, Serpula lacrymans var. lacrymans S7.3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F8PFA4_SERL3	F8PLE2_SERL3	F8PFA4	F8PLE2	ATP-grasp domain-containing protein.	ATP-grasp domain-containing protein.	0.999
F8PFA4_SERL3	F8Q8W1_SERL3	F8PFA4	F8Q8W1	ATP-grasp domain-containing protein.	Uncharacterized protein.	0.675
F8PFG2_SERL3	F8PG33_SERL3	F8PFG2	F8PG33	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Uncharacterized protein.	0.764
F8PFG2_SERL3	F8Q296_SERL3	F8PFG2	F8Q296	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Uncharacterized protein.	0.763
F8PFG2_SERL3	F8Q8W1_SERL3	F8PFG2	F8Q8W1	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Uncharacterized protein.	0.922
F8PFG2_SERL3	F8QHM8_SERL3	F8PFG2	F8QHM8	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.781
F8PG33_SERL3	F8PFG2_SERL3	F8PG33	F8PFG2	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.764
F8PG33_SERL3	F8Q296_SERL3	F8PG33	F8Q296	Uncharacterized protein.	Uncharacterized protein.	0.531
F8PG33_SERL3	F8Q8W1_SERL3	F8PG33	F8Q8W1	Uncharacterized protein.	Uncharacterized protein.	0.813
F8PG33_SERL3	F8QHM8_SERL3	F8PG33	F8QHM8	Uncharacterized protein.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.801
F8PLE2_SERL3	F8PFA4_SERL3	F8PLE2	F8PFA4	ATP-grasp domain-containing protein.	ATP-grasp domain-containing protein.	0.999
F8PLE2_SERL3	F8PS33_SERL3	F8PLE2	F8PS33	ATP-grasp domain-containing protein.	Uncharacterized protein.	0.793
F8PLE2_SERL3	F8Q296_SERL3	F8PLE2	F8Q296	ATP-grasp domain-containing protein.	Uncharacterized protein.	0.532
F8PLE2_SERL3	F8Q2N8_SERL3	F8PLE2	F8Q2N8	ATP-grasp domain-containing protein.	Uncharacterized protein.	0.793
F8PLE2_SERL3	F8Q8W1_SERL3	F8PLE2	F8Q8W1	ATP-grasp domain-containing protein.	Uncharacterized protein.	0.764
F8PS33_SERL3	F8PLE2_SERL3	F8PS33	F8PLE2	Uncharacterized protein.	ATP-grasp domain-containing protein.	0.793
F8PS33_SERL3	F8Q296_SERL3	F8PS33	F8Q296	Uncharacterized protein.	Uncharacterized protein.	0.798
F8PS33_SERL3	F8Q2N8_SERL3	F8PS33	F8Q2N8	Uncharacterized protein.	Uncharacterized protein.	0.941
F8PS33_SERL3	F8Q8W1_SERL3	F8PS33	F8Q8W1	Uncharacterized protein.	Uncharacterized protein.	0.710
F8Q296_SERL3	F8PFG2_SERL3	F8Q296	F8PFG2	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.763