140 items (Erinaceus europaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CWC25	pre-mRNA-splicing factor CWC25 homolog. (322 aa)
	PRPF6	pre-mRNA processing factor 6. (938 aa)
	TXNL4B	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (146 aa)
	ZCRB1	Zinc finger CCHC-type and RNA-binding motif-containing protein 1. (215 aa)
	CRNKL1	Crooked neck-like protein 1. (744 aa)
	CD2BP2	CD2 cytoplasmic tail binding protein 2. (343 aa)
	DHX29	DExH-box helicase 29. (1367 aa)
	SF3B1	Splicing factor 3B subunit 1 isoform X1. (1299 aa)
	RBMX2	RNA-binding motif protein, X-linked 2 isoform X1. (211 aa)
	ZMAT5	Zinc finger matrin-type protein 5 isoform X2. (165 aa)
	PPIL4	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (490 aa)
	SF1	Splicing factor 1 isoform X1. (393 aa)
	ENSEEUP00000001055	annotation not available (315 aa)
	DDX1	ATP-dependent RNA helicase DDX1. (730 aa)
	CTNNBL1	Beta-catenin-like protein 1. (568 aa)
	RBM6	RNA-binding protein 6 isoform X2. (1024 aa)
	ENSEEUP00000001752	annotation not available (65 aa)
	BUD31	Protein BUD31 homolog. (144 aa)
	CWC15	Spliceosome-associated protein CWC15 homolog. (231 aa)
	DHX38	pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1119 aa)
	CDC40	pre-mRNA-processing factor 17. (568 aa)
	SON	Protein SON isoform X8. (2377 aa)
	DDX17	Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family. (725 aa)
	PPIL2	Peptidyl-prolyl cis-trans isomerase-like 2. (520 aa)
	DDX3X	ATP-dependent RNA helicase DDX3X isoform X4; Belongs to the DEAD box helicase family. (647 aa)
	PHAX	Phosphorylated adapter RNA export protein. (343 aa)
	C9orf78	Chromosome 9 open reading frame 78. (259 aa)
	SF3A1	Splicing factor 3A subunit 1. (701 aa)
	ENSEEUP00000002929	annotation not available (556 aa)
	LOC103117449	Leucine-rich repeat-containing protein 51 isoform X3. (192 aa)
	DDX46	Probable ATP-dependent RNA helicase DDX46. (864 aa)
	ENSEEUP00000003510	annotation not available (586 aa)
	AQR	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1517 aa)
	LRMDA	Leucine-rich repeat-containing protein C10orf11 homolog. (226 aa)
	RBM39	RNA-binding protein 39 isoform X3. (530 aa)
	SNRPA1	LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein A. (254 aa)
	NKAP	NF-kappa-B-activating protein. (411 aa)
	ENSEEUP00000004107	annotation not available (63 aa)
	NCBP2L	Nuclear cap binding protein subunit 2 like. (152 aa)
	WBP4	WW domain-binding protein 4. (347 aa)
	LUC7L3	Luc7-like protein 3 isoform X2. (432 aa)
	DHX15	pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 isoform X1. (795 aa)
	DHX57	Putative ATP-dependent RNA helicase DHX57 isoform X1. (1312 aa)
	ENSEEUP00000004366	annotation not available (627 aa)
	ENSEEUP00000004418	annotation not available (383 aa)
	DHX8	ATP-dependent RNA helicase DHX8 isoform X2. (1220 aa)
	DHX9	ATP-dependent RNA helicase A isoform X1. (1265 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (89 aa)
	ENSEEUP00000004679	annotation not available (424 aa)
	LOC103126981	UPF0692 protein C19orf54 homolog. (179 aa)
	CWC22	pre-mRNA-splicing factor CWC22 homolog. (897 aa)
	RBM22	pre-mRNA-splicing factor RBM22. (419 aa)
	PPIH	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (175 aa)
	SNRNP70	U1 small nuclear ribonucleoprotein 70 kDa. (437 aa)
	DDX50	ATP-dependent RNA helicase DDX50 isoform X1. (735 aa)
	ENSEEUP00000005348	annotation not available (642 aa)
	DDX21	Nucleolar RNA helicase 2. (697 aa)
	PRPF31	U4/U6 small nuclear ribonucleoprotein Prp31 isoform X3. (384 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
	LOC103115403	UPF0562 protein C7orf55 homolog. (141 aa)
	PRR3	Proline-rich protein 3 isoform X2. (244 aa)
	SLU7	pre-mRNA-splicing factor SLU7. (586 aa)
	DHX35	Probable ATP-dependent RNA helicase DHX35 isoform X1. (707 aa)
	PPIG	Peptidyl-prolyl cis-trans isomerase G. (671 aa)
	RBM41	RNA-binding protein 41. (409 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
	PRPF4B	Serine/threonine-protein kinase PRP4 homolog. (1004 aa)
	CDC5L	Cell division cycle 5-like protein. (801 aa)
	SNW1	SNW domain-containing protein 1. (536 aa)
	PRPF40B	pre-mRNA-processing factor 40 homolog B isoform X3. (772 aa)
	PRPF3	U4/U6 small nuclear ribonucleoprotein Prp3. (681 aa)
	WDR53	WD repeat-containing protein 53. (358 aa)
	RBM25	RNA-binding protein 25. (841 aa)
	LOC103123420	Small nuclear ribonucleoprotein-associated protein. (239 aa)
	PRPF4	pre-mRNA processing factor 4. (458 aa)
	PRPF19	pre-mRNA-processing factor 19. (504 aa)
	ZMAT2	Zinc finger matrin-type protein 2. (152 aa)
	ENSEEUP00000007143	annotation not available (188 aa)
	NSRP1	Nuclear speckle splicing regulatory protein 1. (552 aa)
	USP39	U4/U6.U5 tri-snRNP-associated protein 2 isoform X1. (563 aa)
	ENSEEUP00000007508	annotation not available (268 aa)
	PRPF39	pre-mRNA-processing factor 39 isoform X2. (527 aa)
	YJU2	YJU2 splicing factor homolog. (231 aa)
	SNRNP27	U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein. (155 aa)
	PRKRIP1	PRKR-interacting protein 1. (153 aa)
	YTHDC2	Probable ATP-dependent RNA helicase YTHDC2. (1411 aa)
	ENSEEUP00000007892	annotation not available (415 aa)
	ENSEEUP00000007978	annotation not available (156 aa)
	WDR70	WD repeat domain 70. (566 aa)
	GPKOW	G patch domain and KOW motifs-containing protein isoform X2. (472 aa)
	TXNL4A	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (91 aa)
	DHX34	Probable ATP-dependent RNA helicase DHX34. (1116 aa)
	SRRT	Serrate RNA effector molecule homolog. (870 aa)
	DDX42	ATP-dependent RNA helicase DDX42 isoform X2. (734 aa)
	BUD13	BUD13 homolog. (538 aa)
	PPIL1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (106 aa)
	DDX23	Probable ATP-dependent RNA helicase DDX23. (822 aa)
	ENSEEUP00000008944	annotation not available (395 aa)
	ENSEEUP00000009063	annotation not available (857 aa)
	PPIE	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (279 aa)
	DHX36	ATP-dependent RNA helicase DHX36 isoform X1. (1007 aa)
	HTATSF1	HIV Tat-specific factor 1. (761 aa)
	LSM11	U7 snRNA-associated Sm-like protein LSm11. (210 aa)
	ENSEEUP00000010068	annotation not available (386 aa)
	CWF19L2	CWF19-like protein 2. (740 aa)
	EFTUD2	116 kDa U5 small nuclear ribonucleoprotein component. (881 aa)
	DHX16	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16. (887 aa)
	CWC27	Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1. (472 aa)
	LSM10	U7 snRNA-associated Sm-like protein LSm10 isoform X1. (123 aa)
	SMU1	WD40 repeat-containing protein SMU1. (513 aa)
	ENSEEUP00000011134	annotation not available (2333 aa)
	SNRNP200	U5 small nuclear ribonucleoprotein 200 kDa helicase. (2018 aa)
	LOC103115402	Putative RNA-binding protein Luc7-like 2 isoform X4. (367 aa)
	ENSEEUP00000011279	annotation not available (475 aa)
	WBP11	WW domain-binding protein 11. (639 aa)
	SDE2	Protein SDE2 homolog. (449 aa)
	RNPC3	RNA-binding protein 40 isoform X1. (64 aa)
	SNRPF	Small nuclear ribonucleoprotein F. (85 aa)
	DDX59	Probable ATP-dependent RNA helicase DDX59 isoform X1. (528 aa)
	SNRPB2	U2 small nuclear ribonucleoprotein B'. (225 aa)
	SRRM1	Serine/arginine repetitive matrix protein 1 isoform X1. (912 aa)
	CCAR1	Cell division cycle and apoptosis regulator protein 1. (1107 aa)
	ENSEEUP00000012819	annotation not available (126 aa)
	SRRM2	Serine/arginine repetitive matrix protein 2 isoform X1. (2615 aa)
	ENSEEUP00000013058	annotation not available (891 aa)
	ENSEEUP00000013081	annotation not available (358 aa)
	SNIP1	Smad nuclear-interacting protein 1. (286 aa)
	SNRPC	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (175 aa)
	ZCCHC17	Nucleolar protein of 40 kDa. (240 aa)
	TCERG1	Transcription elongation regulator 1 isoform X4. (1003 aa)
	SYF2	pre-mRNA-splicing factor SYF2. (183 aa)
	SNRPA	U1 small nuclear ribonucleoprotein A isoform X1. (282 aa)
	MFAP1	Microfibrillar-associated protein 1. (412 aa)
	PLRG1	Pleiotropic regulator 1. (502 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
	RBM23	Probable RNA-binding protein 23 isoform X1. (444 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (284 aa)
	SF3B3	Splicing factor 3B subunit 3. (1216 aa)
	TFIP11	Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (738 aa)
	NCBP1	Nuclear cap-binding protein subunit 1. (747 aa)

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR	BUD13	ENSEEUP00000003713	ENSEEUP00000008511	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	BUD13 homolog.	0.596
AQR	BUD31	ENSEEUP00000003713	ENSEEUP00000001881	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Protein BUD31 homolog.	0.994
AQR	CDC40	ENSEEUP00000003713	ENSEEUP00000002017	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-processing factor 17.	0.978
AQR	CDC5L	ENSEEUP00000003713	ENSEEUP00000006665	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cell division cycle 5-like protein.	0.988
AQR	CRNKL1	ENSEEUP00000003713	ENSEEUP00000000366	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Crooked neck-like protein 1.	0.997
AQR	CTNNBL1	ENSEEUP00000003713	ENSEEUP00000001494	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Beta-catenin-like protein 1.	0.589
AQR	CWC15	ENSEEUP00000003713	ENSEEUP00000001930	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Spliceosome-associated protein CWC15 homolog.	0.928
AQR	CWC22	ENSEEUP00000003713	ENSEEUP00000004896	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor CWC22 homolog.	0.890
AQR	CWC25	ENSEEUP00000003713	ENSEEUP00000000014	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor CWC25 homolog.	0.589
AQR	CWC27	ENSEEUP00000003713	ENSEEUP00000010911	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1.	0.751
AQR	CWF19L2	ENSEEUP00000003713	ENSEEUP00000010085	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWF19-like protein 2.	0.919
AQR	DDX23	ENSEEUP00000003713	ENSEEUP00000008818	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Probable ATP-dependent RNA helicase DDX23.	0.530
AQR	DHX15	ENSEEUP00000003713	ENSEEUP00000004346	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 isoform X1.	0.846
AQR	DHX16	ENSEEUP00000003713	ENSEEUP00000010880	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16.	0.713
AQR	DHX34	ENSEEUP00000003713	ENSEEUP00000008259	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Probable ATP-dependent RNA helicase DHX34.	0.810
AQR	DHX35	ENSEEUP00000003713	ENSEEUP00000005894	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Probable ATP-dependent RNA helicase DHX35 isoform X1.	0.649
AQR	DHX38	ENSEEUP00000003713	ENSEEUP00000001960	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16.	0.613
AQR	DHX8	ENSEEUP00000003713	ENSEEUP00000004449	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	ATP-dependent RNA helicase DHX8 isoform X2.	0.965
AQR	DHX9	ENSEEUP00000003713	ENSEEUP00000004476	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	ATP-dependent RNA helicase A isoform X1.	0.584
AQR	EFTUD2	ENSEEUP00000003713	ENSEEUP00000010179	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	116 kDa U5 small nuclear ribonucleoprotein component.	0.987