STRINGSTRING
SF3B1 SF3B1 ENSEEUP00000001752 ENSEEUP00000001752 SF3A1 SF3A1 DDX46 DDX46 SNRPA1 SNRPA1 SNRPD1 SNRPD1 ENSEEUP00000004679 ENSEEUP00000004679 SNRNP70 SNRNP70 SNRPE SNRPE LOC103123420 LOC103123420 ENSEEUP00000011279 ENSEEUP00000011279 SNRPF SNRPF SNRPB2 SNRPB2 ENSEEUP00000012819 ENSEEUP00000012819 ENSEEUP00000013058 ENSEEUP00000013058 SNRPC SNRPC SNRPA SNRPA SNRPD3 SNRPD3 SF3B3 SF3B3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SF3B1Splicing factor 3B subunit 1 isoform X1. (1299 aa)
ENSEEUP00000001752annotation not available (65 aa)
SF3A1Splicing factor 3A subunit 1. (701 aa)
DDX46Probable ATP-dependent RNA helicase DDX46. (864 aa)
SNRPA1LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein A. (254 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (89 aa)
ENSEEUP00000004679annotation not available (424 aa)
SNRNP70U1 small nuclear ribonucleoprotein 70 kDa. (437 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
LOC103123420Small nuclear ribonucleoprotein-associated protein. (239 aa)
ENSEEUP00000011279annotation not available (475 aa)
SNRPFSmall nuclear ribonucleoprotein F. (85 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
ENSEEUP00000012819annotation not available (126 aa)
ENSEEUP00000013058annotation not available (891 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (175 aa)
SNRPAU1 small nuclear ribonucleoprotein A isoform X1. (282 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
SF3B3Splicing factor 3B subunit 3. (1216 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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