STRINGSTRING
ENSEEUP00000000369 ENSEEUP00000000369 WDHD1 WDHD1 BLM BLM RAD51B RAD51B RAD51D RAD51D RAD51C RAD51C RPA1 RPA1 TDRD3 TDRD3 RAD51AP1 RAD51AP1 GEN1 GEN1 WRN WRN ENSEEUP00000004813 ENSEEUP00000004813 FANCM FANCM RAD52 RAD52 XRCC3 XRCC3 EXO1 EXO1 DNA2 DNA2 ENSEEUP00000008566 ENSEEUP00000008566 BRCA2 BRCA2 ENSEEUP00000009711 ENSEEUP00000009711 RMI1 RMI1 BRIP1 BRIP1 TOP3A TOP3A ATAD5 ATAD5 DMC1 DMC1 MEIOB MEIOB PALB2 PALB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSEEUP00000000369annotation not available (121 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (1130 aa)
BLMBloom syndrome protein. (1383 aa)
RAD51BDNA repair protein RAD51 homolog 2. (344 aa)
RAD51DDNA repair protein RAD51 homolog 4 isoform X1. (327 aa)
RAD51CDNA repair protein RAD51 homolog 3. (377 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
TDRD3Tudor domain-containing protein 3. (650 aa)
RAD51AP1RAD51-associated protein 1 isoform X1. (201 aa)
GEN1Flap endonuclease GEN homolog 1. (871 aa)
WRNLOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. (1264 aa)
ENSEEUP00000004813annotation not available (1112 aa)
FANCMFanconi anemia group M protein. (1962 aa)
RAD52DNA repair protein RAD52 homolog isoform X1. (391 aa)
XRCC3DNA repair protein XRCC3 isoform X2. (254 aa)
EXO1Exonuclease 1. (772 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (924 aa)
ENSEEUP00000008566annotation not available (709 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3345 aa)
ENSEEUP00000009711annotation not available (333 aa)
RMI1recQ-mediated genome instability protein 1. (608 aa)
BRIP1Fanconi anemia group J protein. (1239 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (943 aa)
ATAD5ATPase family AAA domain containing 5. (1813 aa)
DMC1Meiotic recombination protein DMC1/LIM15 homolog isoform X1; Belongs to the RecA family. (323 aa)
MEIOBMeiosis-specific with OB domain-containing protein. (214 aa)
PALB2Partner and localizer of BRCA2 isoform X2. (1173 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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