(19 nodes) Nucleotide-excision repair complex, and ATP-dependent chromatin remodeler activity network (Erinaceus europaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAD18	E3 ubiquitin-protein ligase RAD18. (440 aa)
	ENSEEUP00000001566	annotation not available (497 aa)
	CHD1L	chromodomain-helicase-DNA-binding protein 1-like isoform X1. (873 aa)
	ERCC8	DNA excision repair protein ERCC-8. (395 aa)
	ENSEEUP00000004944	annotation not available (389 aa)
	XPA	DNA repair protein complementing XP-A cells. (214 aa)
	ERCC4	DNA repair endonuclease XPF. (918 aa)
	RAD54B	DNA repair and recombination protein RAD54B. (904 aa)
	RAD54L	DNA repair and recombination protein RAD54-like. (747 aa)
	ERCC6	DNA excision repair protein ERCC-6. (1468 aa)
	ERCC6L2	LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6-like 2. (708 aa)
	ENSEEUP00000010090	annotation not available (245 aa)
	UBE2A	Ubiquitin-conjugating enzyme E2 B isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	ENSEEUP00000011189	annotation not available (1002 aa)
	WDR76	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (604 aa)
	ERCC1	DNA excision repair protein ERCC-1 isoform X2. (232 aa)
	UBE2V2	Ubiquitin conjugating enzyme E2 V2. (144 aa)
	XPC	DNA repair protein complementing XP-C cells. (912 aa)
	HLTF	Helicase-like transcription factor isoform X2. (1009 aa)

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD1L	ENSEEUP00000001566	ENSEEUP00000002825	ENSEEUP00000001566	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	annotation not available	0.526
CHD1L	ENSEEUP00000004944	ENSEEUP00000002825	ENSEEUP00000004944	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	annotation not available	0.929
CHD1L	ENSEEUP00000010090	ENSEEUP00000002825	ENSEEUP00000010090	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	annotation not available	0.485
CHD1L	ENSEEUP00000011189	ENSEEUP00000002825	ENSEEUP00000011189	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	annotation not available	0.929
CHD1L	ERCC1	ENSEEUP00000002825	ENSEEUP00000011651	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA excision repair protein ERCC-1 isoform X2.	0.595
CHD1L	ERCC4	ENSEEUP00000002825	ENSEEUP00000007144	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA repair endonuclease XPF.	0.741
CHD1L	ERCC6	ENSEEUP00000002825	ENSEEUP00000007796	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA excision repair protein ERCC-6.	0.690
CHD1L	ERCC6L2	ENSEEUP00000002825	ENSEEUP00000008533	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6-like 2.	0.536
CHD1L	ERCC8	ENSEEUP00000002825	ENSEEUP00000004017	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA excision repair protein ERCC-8.	0.561
CHD1L	HLTF	ENSEEUP00000002825	ENSEEUP00000014144	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	Helicase-like transcription factor isoform X2.	0.586
CHD1L	RAD18	ENSEEUP00000002825	ENSEEUP00000000205	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	E3 ubiquitin-protein ligase RAD18.	0.579
CHD1L	RAD54B	ENSEEUP00000002825	ENSEEUP00000007364	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA repair and recombination protein RAD54B.	0.649
CHD1L	RAD54L	ENSEEUP00000002825	ENSEEUP00000007423	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA repair and recombination protein RAD54-like.	0.428
CHD1L	UBE2V2	ENSEEUP00000002825	ENSEEUP00000013404	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	Ubiquitin conjugating enzyme E2 V2.	0.736
CHD1L	WDR76	ENSEEUP00000002825	ENSEEUP00000011395	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.	0.700
CHD1L	XPA	ENSEEUP00000002825	ENSEEUP00000005331	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA repair protein complementing XP-A cells.	0.944
CHD1L	XPC	ENSEEUP00000002825	ENSEEUP00000013619	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	DNA repair protein complementing XP-C cells.	0.796
ENSEEUP00000001566	CHD1L	ENSEEUP00000001566	ENSEEUP00000002825	annotation not available	chromodomain-helicase-DNA-binding protein 1-like isoform X1.	0.526
ENSEEUP00000001566	ENSEEUP00000004944	ENSEEUP00000001566	ENSEEUP00000004944	annotation not available	annotation not available	0.560
ENSEEUP00000001566	ENSEEUP00000010090	ENSEEUP00000001566	ENSEEUP00000010090	annotation not available	annotation not available	0.900