STRINGSTRING
DBR1 DBR1 ENSEEUP00000000077 ENSEEUP00000000077 USB1 USB1 DIS3 DIS3 ENPP2 ENPP2 EXD3 EXD3 RPP14 RPP14 ERI1 ERI1 KHNYN KHNYN NYNRIN NYNRIN ENSEEUP00000000613 ENSEEUP00000000613 RAD50 RAD50 AGO4 AGO4 INTS11 INTS11 PAN2 PAN2 EXOSC10 EXOSC10 EXD1 EXD1 LOC103126924 LOC103126924 TSNAX TSNAX DDX1 DDX1 NUDT12 NUDT12 RAD51C RAD51C RBBP8 RBBP8 ENSEEUP00000001957 ENSEEUP00000001957 ENSEEUP00000002093 ENSEEUP00000002093 ENSEEUP00000002209 ENSEEUP00000002209 ENSEEUP00000002396 ENSEEUP00000002396 CNOT2 CNOT2 ENSEEUP00000002802 ENSEEUP00000002802 ZC3H12B ZC3H12B SMG6 SMG6 REXO5 REXO5 SWT1 SWT1 ASTE1 ASTE1 ENSEEUP00000003518 ENSEEUP00000003518 PIWIL1 PIWIL1 LOC103108114 LOC103108114 ENSEEUP00000003596 ENSEEUP00000003596 EXOG EXOG MARF1 MARF1 SAMHD1 SAMHD1 HELZ2 HELZ2 TTC38 TTC38 ENSEEUP00000004392 ENSEEUP00000004392 GEN1 GEN1 ENSEEUP00000004547 ENSEEUP00000004547 WRN WRN DNASE1L3 DNASE1L3 AGO1 AGO1 DXO DXO ENSEEUP00000004944 ENSEEUP00000004944 LOC103107805 LOC103107805 DCLRE1A DCLRE1A FANCM FANCM TSEN34 TSEN34 ZC3H12C ZC3H12C PNLDC1 PNLDC1 DCP2 DCP2 ZC3H12A ZC3H12A PIWIL2 PIWIL2 CNOT1 CNOT1 ERN1 ERN1 FAN1 FAN1 DROSHA DROSHA ENSEEUP00000006070 ENSEEUP00000006070 ERI3 ERI3 TDP1 TDP1 EXD2 EXD2 AEN AEN ENPP1 ENPP1 AGO3 AGO3 ENSEEUP00000006512 ENSEEUP00000006512 ERI2 ERI2 ENSEEUP00000006928 ENSEEUP00000006928 ERCC4 ERCC4 DNASE2B DNASE2B MRPL44 MRPL44 N4BP1 N4BP1 RNASEH2A RNASEH2A RAD1 RAD1 MRE11 MRE11 DNASE2 DNASE2 TSEN54 TSEN54 ENSEEUP00000007832 ENSEEUP00000007832 EXO1 EXO1 ZNF215 ZNF215 DNA2 DNA2 XRN2 XRN2 ANGEL2 ANGEL2 ENSEEUP00000008832 ENSEEUP00000008832 RCL1 RCL1 RPP21 RPP21 ENSEEUP00000009111 ENSEEUP00000009111 ELAC1 ELAC1 ENSEEUP00000009489 ENSEEUP00000009489 PARN PARN ENSEEUP00000009600 ENSEEUP00000009600 EME1 EME1 APTX APTX TDP2 TDP2 ELAC2 ELAC2 CNOT7 CNOT7 POLG POLG TATDN3 TATDN3 CNOT8 CNOT8 ZRANB3 ZRANB3 LAS1L LAS1L XRN1 XRN1 RNASEL RNASEL ENDOU ENDOU RPP40 RPP40 REXO4 REXO4 RNASE6 RNASE6 ENSEEUP00000011189 ENSEEUP00000011189 G3BP1 G3BP1 N4BP2 N4BP2 APEX1 APEX1 TATDN1 TATDN1 ERCC1 ERCC1 POP4 POP4 APEX2 APEX2 ENSEEUP00000012389 ENSEEUP00000012389 NOCT NOCT TSN TSN PLD6 PLD6 C12orf10 C12orf10 POP5 POP5 NOB1 NOB1 RPS3 RPS3 MEIOB MEIOB RPP38 RPP38 SND1 SND1 ENSEEUP00000013504 ENSEEUP00000013504 PAN3 PAN3 XRCC1 XRCC1 CNOT6 CNOT6 TOE1 TOE1 CPSF3 CPSF3 RNASE4 RNASE4 MUS81 MUS81 PNPT1 PNPT1 REXO2 REXO2 DFFB DFFB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DBR1Lariat debranching enzyme isoform X1. (544 aa)
ENSEEUP00000000077annotation not available (504 aa)
USB1U6 snRNA biogenesis phosphodiesterase 1. (265 aa)
DIS3Exosome complex exonuclease RRP44 isoform X1; Belongs to the RNR ribonuclease family. (890 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X1. (913 aa)
EXD3Exonuclease mut-7 homolog. (718 aa)
RPP14Ribonuclease P protein subunit p14. (123 aa)
ERI13'-5' exoribonuclease 1. (313 aa)
KHNYNProtein KHNYN isoform X1. (658 aa)
NYNRINProtein NYNRIN. (409 aa)
ENSEEUP00000000613annotation not available (848 aa)
RAD50DNA repair protein RAD50 isoform X1. (1311 aa)
AGO4Argonaute RISC component 4. (861 aa)
INTS11Integrator complex subunit 11 isoform X1. (600 aa)
PAN2poly(A) specific ribonuclease subunit PAN2. (1191 aa)
EXOSC10Exosome component 10 isoform X2. (814 aa)
EXD1piRNA biogenesis protein EXD1. (500 aa)
LOC103126924Ribonuclease 7-like; Belongs to the pancreatic ribonuclease family. (156 aa)
TSNAXTranslin-associated protein X. (288 aa)
DDX1ATP-dependent RNA helicase DDX1. (730 aa)
NUDT12Nudix hydrolase 12. (462 aa)
RAD51CDNA repair protein RAD51 homolog 3. (377 aa)
RBBP8DNA endonuclease RBBP8. (903 aa)
ENSEEUP00000001957annotation not available (350 aa)
ENSEEUP00000002093annotation not available (1887 aa)
ENSEEUP00000002209annotation not available (245 aa)
ENSEEUP00000002396annotation not available (578 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
ENSEEUP00000002802annotation not available (964 aa)
ZC3H12BProbable ribonuclease ZC3H12B. (446 aa)
SMG6Telomerase-binding protein EST1A isoform X1. (1404 aa)
REXO5Putative RNA exonuclease NEF-sp. (728 aa)
SWT1Transcriptional protein SWT1. (876 aa)
ASTE1Protein asteroid homolog 1. (485 aa)
ENSEEUP00000003518annotation not available (658 aa)
PIWIL1Piwi-like protein 1 isoform X1; Belongs to the argonaute family. (860 aa)
LOC103108114LOW QUALITY PROTEIN: schlafen family member 13-like. (535 aa)
ENSEEUP00000003596annotation not available (1865 aa)
EXOGNuclease EXOG, mitochondrial isoform X1. (315 aa)
MARF1Meiosis arrest female protein 1 isoform X1. (1719 aa)
SAMHD1Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. (623 aa)
HELZ2Helicase with zinc finger domain 2 isoform X1. (2442 aa)
TTC38Tetratricopeptide repeat domain 38. (458 aa)
ENSEEUP00000004392annotation not available (410 aa)
GEN1Flap endonuclease GEN homolog 1. (871 aa)
ENSEEUP00000004547annotation not available (166 aa)
WRNLOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase. (1264 aa)
DNASE1L3Deoxyribonuclease; Belongs to the DNase I family. (218 aa)
AGO1Protein argonaute-1; Belongs to the argonaute family. (857 aa)
DXODecapping and exoribonuclease protein. (311 aa)
ENSEEUP00000004944annotation not available (389 aa)
LOC103107805Serine/threonine-protein kinase/endoribonuclease IRE2-like. (946 aa)
DCLRE1ADNA cross-link repair 1A protein. (1003 aa)
FANCMFanconi anemia group M protein. (1962 aa)
TSEN34tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (281 aa)
ZC3H12CProbable ribonuclease ZC3H12C. (571 aa)
PNLDC1poly(A)-specific ribonuclease PARN-like domain-containing protein 1. (414 aa)
DCP2m7GpppN-mRNA hydrolase isoform X1. (423 aa)
ZC3H12ARibonuclease ZC3H12A. (500 aa)
PIWIL2Piwi-like protein 2; Belongs to the argonaute family. (882 aa)
CNOT1CCR4-NOT transcription complex subunit 1 isoform X4. (2375 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (953 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1007 aa)
DROSHARibonuclease 3. (1372 aa)
ENSEEUP00000006070annotation not available (342 aa)
ERI3ERI1 exoribonuclease 3 isoform X6. (362 aa)
TDP1tyrosyl-DNA phosphodiesterase 1. (610 aa)
EXD2Exonuclease 3'-5' domain-containing protein 2. (496 aa)
AENApoptosis-enhancing nuclease. (276 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (915 aa)
AGO3Protein argonaute-3; Belongs to the argonaute family. (860 aa)
ENSEEUP00000006512annotation not available (769 aa)
ERI2ERI1 exoribonuclease 2. (676 aa)
ENSEEUP00000006928annotation not available (188 aa)
ERCC4DNA repair endonuclease XPF. (918 aa)
DNASE2BDeoxyribonuclease-2-beta isoform X1. (182 aa)
MRPL4439S ribosomal protein L44, mitochondrial. (330 aa)
N4BP1NEDD4 binding protein 1. (930 aa)
RNASEH2ARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (294 aa)
RAD1Cell cycle checkpoint protein RAD1. (281 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (656 aa)
DNASE2Deoxyribonuclease-2-alpha. (358 aa)
TSEN54tRNA-splicing endonuclease subunit Sen54. (456 aa)
ENSEEUP00000007832annotation not available (853 aa)
EXO1Exonuclease 1. (772 aa)
ZNF215Zinc finger protein 215. (516 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (924 aa)
XRN25'-3' exoribonuclease 2. (944 aa)
ANGEL2Protein angel homolog 2. (544 aa)
ENSEEUP00000008832annotation not available (514 aa)
RCL1RNA 3'-terminal phosphate cyclase-like protein. (345 aa)
RPP21Ribonuclease P protein subunit p21 isoform X1. (147 aa)
ENSEEUP00000009111annotation not available (262 aa)
ELAC1Zinc phosphodiesterase ELAC protein 1. (363 aa)
ENSEEUP00000009489annotation not available (605 aa)
PARNpoly(A)-specific ribonuclease. (635 aa)
ENSEEUP00000009600annotation not available (235 aa)
EME1Crossover junction endonuclease EME1 isoform X1. (563 aa)
APTXAprataxin isoform X2. (306 aa)
TDP2tyrosyl-DNA phosphodiesterase 2. (356 aa)
ELAC2Zinc phosphodiesterase ELAC protein 2 isoform X2. (814 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (242 aa)
POLGDNA polymerase subunit gamma-1. (1125 aa)
TATDN3TatD DNase domain containing 3. (221 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (188 aa)
ZRANB3DNA annealing helicase and endonuclease ZRANB3 isoform X1. (1000 aa)
LAS1LRibosomal biogenesis protein LAS1L isoform X1. (689 aa)
XRN15'-3' exoribonuclease 1. (1697 aa)
RNASEL2-5A-dependent ribonuclease. (668 aa)
ENDOUpoly(U)-specific endoribonuclease isoform X2. (348 aa)
RPP40Ribonuclease P protein subunit p40 isoform X1. (296 aa)
REXO4RNA exonuclease 4. (325 aa)
RNASE6LOW QUALITY PROTEIN: ribonuclease K6; Belongs to the pancreatic ribonuclease family. (156 aa)
ENSEEUP00000011189annotation not available (1002 aa)
G3BP1Ras GTPase-activating protein-binding protein 1. (463 aa)
N4BP2NEDD4-binding protein 2. (1684 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (288 aa)
TATDN1Putative deoxyribonuclease TATDN1 isoform X2. (255 aa)
ERCC1DNA excision repair protein ERCC-1 isoform X2. (232 aa)
POP4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (200 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (509 aa)
ENSEEUP00000012389annotation not available (297 aa)
NOCTNocturnin. (272 aa)
TSNTranslin isoform X1. (174 aa)
PLD6Mitochondrial cardiolipin hydrolase. (248 aa)
C12orf10UPF0160 protein MYG1, mitochondrial. (373 aa)
POP5POP5 homolog, ribonuclease P/MRP subunit. (170 aa)
NOB1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (417 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
MEIOBMeiosis-specific with OB domain-containing protein. (214 aa)
RPP38Ribonuclease P protein subunit p38. (282 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
ENSEEUP00000013504annotation not available (136 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (701 aa)
XRCC1DNA repair protein XRCC1 isoform X2. (631 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (556 aa)
TOE1Target of EGR1 protein 1. (509 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3. (683 aa)
RNASE4Ribonuclease 4 isoform X1; Belongs to the pancreatic ribonuclease family. (143 aa)
MUS81Crossover junction endonuclease MUS81 isoform X3. (464 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (787 aa)
REXO2Oligoribonuclease, mitochondrial. (160 aa)
DFFBDNAation factor subunit beta. (338 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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